What is the strongest concentration that is ok for a vial of Tirzepatide?

[HoopFan]

I’m trying to help my friend out, but FFS my brain aint brainin’ today.

She has been on 10mg of Zepbound. She is a newbie greyzoner now. She would rather not have to inject a large dose each time, which I get. I got her pushed toward filtering, and sterile new vials.

Anyway what concentration is considered a danger zone for Tirz? 40mg/ml? 60mg/mL?

I think she is considering two 30mg vials with 1ml of BAC total. That would put her at 60mg/mL in her new vial. I’ve only gone as high as 30mg/mL. I even had a dose calculator scream at me when I fat-fingered and accidentally setting it higher than 30mg/mL.

My head is spinning. Help a hound out?

 

[IshimaruKenta]

How much was her vial tested as? 64mg, 69mg (nice) or around there? Technically I've done 1mL of BAC for a 64.21mg vial and only did about 13u.

Better Peptide Calculator

btpepcalc.com

Try this calculator and input the amount that batch was tested at, not 60mg, then add 1mL BAC and you'll see a warning. Keep adding BAC to see when it goes to blue or green. I was fine with 1mL of BAC and less units.

 

[CallieKat]

If she has a 60 mg vial and she takes 10 mg. That’s 6 weeks per vial or you asking something else…

 

[IshimaruKenta]

If she has a 60 mg vial and she takes 10 mg. That’s 6 weeks per vial or you asking something else…

Something else. But it's still not 60.00mg in the vial due to overfill. But they're asking what a safe concentration is. I did 64.21mg/mL and it was fine.

 

[MsGizmo]

If she is adding 1mL to each vial of 30mg and then filtering them both into one vial ... her new filtered vial will contain 60mg in 2mL of fluid. Since her desired dose is 10mg she would want each injection to be 33 units.

OR

If she is is only adding .5mL into each vial then she has a 60mg vial in 1mL of liquid and her desired dose of 10mg would be had in 17units.

 

[HoopFan]

Something else. But it's still not 60.00mg in the vial due to overfill. But they're asking what a safe concentration is. I did 64.21mg/mL and it was fine.

Yeah that’s what I was asking. What was the safest concentration for someone to have once they reconstitute Tirz.

What the hell do people do with those 100mg vials that I’ve seen selling? Holy crap! lol

 

[CallieKat]

Oh asking if 60 mg will dissolve completely in 1 ml? It probably will but I prefer more volume…at least 2-3 ml.

 

[IshimaruKenta]

I don't want to hijack, but they need to be taught about overfill (and very rarely underfill) and to dose based on that. It's never exactly 60.00mg of a peptide in there. You're going to dose incorrectly and either might feel sick or think it's not working.

 

[HoopFan]

If she is adding 1mL to each vial of 30mg and then filtering them both into one vial ... her new filtered vial will contain 60mg in 2mL of fluid. Since her desired dose is 10mg she would want each injection to be 33 units.

She did .5mL for each one and then was gonna combine those in a new vial after filtering.

 

[CallieKat]

If it dissolves then it should be okay…make sure there’s not much liquid left behind…those last drops will be concentrated…I don’t like worrying about how much API I may have left behind…

 

[IshimaruKenta]

Yeah that’s what I was asking. What was the safest concentration for someone to have once they reconstitute Tirz.

What the hell do people do with those 100mg vials that I’ve seen selling? Holy crap! lol

There are 120mg vials that are probably overfilled to 130 or maybe even 140mg. No idea how you'd use that unless you're sharing.

I've done 64.21mg/mL without any issues. Just depends on how many units they want to inject.

 

[IshimaruKenta]

If she is adding 1mL to each vial of 30mg and then filtering them both into one vial ... her new filtered vial will contain 60mg in 2mL of fluid. Since her desired dose is 10mg she would want each injection to be 33 units.

OR

If she is is only adding .5mL into each vial then she has a 60mg vial in 1mL of liquid and her desired dose of 10mg would be had in 17units.

Overfill changes those calculations, so it's not going to just be 17 units. 🤷‍♂️

 

[Airborne Daddy]

If she is adding 1mL to each vial of 30mg and then filtering them both into one vial ... her new filtered vial will contain 60mg in 2mL of fluid. Since her desired dose is 10mg she would want each injection to be 33 units.

OR

If she is is only adding .5mL into each vial then she has a 60mg vial in 1mL of liquid and her desired dose of 10mg would be had in 17units.

It's a 60mg vial. So every 10 units is 6mg.... but they're taking into consideration an over fill of 4 to 9mg which I don't worry about. If I'm pinning 15mg and it's actually 17.3mg or whatever I care not cuz I'll do the same in 5 or 6 days again.

 

[IshimaruKenta]

It's a 60mg vial. So every 10 units is 6mg.... but they're taking into consideration an over fill of 4 to 9mg which I don't worry about. If I'm pinning 15mg and it's actually 17.3mg or whatever I care not cuz I'll do the same in 5 or 6 days again.

I only mention it for people who aren't used to this, just starting out, etc. You're a seasoned veteran so it won't affect you. ❤️

 

[HoopFan]

I gave her two of my 30mg vials, to get her through the month. The over-fill avg for our group testing was 2.xx mg, which means she actually just reconstituted about 65 mg.

So 65mg/mL

Effing math. I’ve been smothered in IT work all day, so now I have the retention of a screen door.

 

[IshimaruKenta]

I gave her two of my 30mg vials, to get her through the month. The over-fill avg for our group testing was 2.xx mg, which means she actually just reconstituted about 65 mg.

So 65mg/mL

Effing math. I’ve been smothered in IT work all day, so now I have the retention of a screen door.

Better Peptide Calculator

btpepcalc.com

Use that, it'll let you know if it's good or cautionary.

 

[HoopFan]

Better Peptide Calculator

btpepcalc.com

Use that, it'll let you know if it's good or cautionary.

If you saw my list of calculators I have bookmarked. lol I use them religiously.

Those weren’t answering the safety question about the actual concentration tho.

 

[IshimaruKenta]

If you saw my list of calculators I have bookmarked. lol I use them religiously.

Those weren’t answering the safety question about the actual concentration tho.

This one will say if it's not safe to use. For example

 

[randompersonrandom]

I've wondered that before; if there's a point at which it's syrupy from too much mannitol in too little water. Then I thought about injecting myself with mannitol syrup, got grossed out, and just went and did something else.

Edit: Well this is concerning. I punched in the NAD+ reconstitution that I've always seen, which is 3 ml in a 500mg vial, and it has super high risk all over the place.

 

[IshimaruKenta]

I've wondered that before; if there's a point at which it's syrupy from too much mannitol in too little water. Then I thought about injecting myself with mannitol syrup, got grossed out, and just went and did something else.

Sounds great on waffles 🧇

 

[HoopFan]

This one will say if it's not safe to use. For example

View attachment 9920

Yeah the Fat Scientist App was like "mrrp mrrp Danger Danger… the normal concentration of Tirzepatide is 7mg/mL and 30 mg/ml. Please double-check your vial label….”

Then it pooped itself.

 

[HoopFan]

I've wondered that before; if there's a point at which it's syrupy from too much mannitol in too little water. Then I thought about injecting myself with mannitol syrup, got grossed out, and just went and did something else.

Edit: Well this is concerning. I punched in the NAD+ reconstitution that I've always seen, which is 3 ml in a 500mg vial, and it has super high risk all over the place.

There is a song to be made….

 

[IshimaruKenta]

Yeah the Fat Scientist App was like "mrrp mrrp Danger Danger… the normal concentration of Tirzepatide is 7mg/mL and 30 mg/ml. Please double-check your vial label….”

Then it pooped itself.

I only mentioned this calculator because it specifically states in red if it's unsafe. Blue if it's optimal and green where it's a-ok. Wasn't trying to shove another calculator down your throat. ❤️

 

[HoopFan]

I only mentioned this calculator because it specifically states in red if it's unsafe. Blue if it's optimal and green where it's a-ok. Wasn't trying to shove another calculator down your throat. ❤️

All good. I appreciate the gesture.

Now lemme post this song for @randompersonrandom ….

 

[randompersonrandom]

All good. I appreciate the gesture.

Now lemme post this song for @randompersonrandom ….

I am in anticipation of being very uncomfortable. I can't imagine what song would include these elements, but I'll bet I won't like it.

 

[HoopFan]

🎵“Tracy’s Monologue (The Mannitol Syrup Song)” 🎵​

A villain-style parody aligned to the original tune - “Escape (The Piña Colada Song)”

You were mixing your peptides,
Thinking everything’s pure.
All your little GLP vials—
You believed they were sure.
You were swirling Mannitol Syrup,
Feeling proud of your blend…
But you never saw me watching,
Right behind you again.

You like that Mannitol Syrup,
And your doses just right—
But I’m the queen of the grey market,
Lurking out of your sight.

So when you’re dosing your GLPs,
Thinking nothing’s amiss…
Just remember your supplier?
Baby—Tracy runs all this.

You thought you found a vendor
Who was clean, verified.
But that “welcome note” you opened?
Yeah, I wrote it with pride.
You kept boasting reconstitution—
How precise you’ve become…
But I choose how pure your batch is,
And I choose what you get done.

Yeah, you love Mannitol Syrup,
All your vials lined up neat—
But your precious little peptides
Only move when I compete.

So when you’re tapping your syringe tip,
Trying not to pull foam…
Know your whole peptide obsession?
Tracy built it—welcome home.

You ran from “grey-market Tracy,”
Thought you slipped from my chain.
But your shipping confirmation
Led me straight to your name.
You can switch to other sellers—
Try escaping my view…
But no matter where you order,
Tracy’s fingerprints are on you.

’Cause you like Mannitol Syrup,
And pretending you’re free…
But those vials in your freezer
All came straight through me.
You can whisper about “quality,”
Claim you research each part…
But Tracy’s in your reconstitution—
Right there from the start.

 

[HoopFan]

Your earworm for the evening

 

[Airborne Daddy]

I only mention it for people who aren't used to this, just starting out, etc. You're a seasoned veteran so it won't affect you. ❤️

No I get that and probably should consider it. I do the math in my head and estimate. Then I forget my calculations and how much bac I added. Started putting tape and sharpie labels on my vials.

Yeah that’s what I was asking. What was the safest concentration for someone to have once they reconstitute Tirz.

What the hell do people do with those 100mg vials that I’ve seen selling? Holy crap! lol

Pin that shit in 5 weeks jk but i do... I think you meant how little bac can you go with a higher mg vial and I don't think it matters unless it's too thick to push, causes pain, redness, irritation... for example I do glutathione intra muscular where it's made to reconstitute with 6ml of bac and get fed into an iv bag like the health and wellness spas do.... I add 3ml of bac and pin 1.5 ml every 3rd day which is pushing it cuz it burns for 20 seconds. I think as long as you add 100 or 150 iu of bac to the glp1 it's OK. Example I have 30mg sema coming and at 1ml or 100iu of bac, that's 3mg of sema every 10 units so I'll go 1.5ml or 150iu bac... now 15 iu= 3mg so I'll do 5iu to stack or 10-15 alone....

 

[randompersonrandom]

Your earworm for the evening

Absolutely not. I reject your offering. Go to your room, you need to think about what you did.

 

[HoopFan]

Absolutely not. I reject your offering. Go to your room, you need to think about what you did.

That tone absolutely and 100% fit your cat’s expression on your profile photo! 🤣🤣