They can't.
If there's any (relatively) large particulate matter in the vials it's going to get stuck in the columns and ruin them. It won't show up on the HPLC either way, but this way it will also cost thousands to fix.
(Paraphrasing from memory their explanation, this is the limit of my...
To be fair I always filter.
I do it because I listened to Ghoul on meso, who is a total fear mongering loudmouth, but he does make good points every now and again.
I'm not worried about bacteria in subq shots, but he showed that immunogenicity could be a realistic concern, so I filter.
It's...
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