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  1. Calm Logic

    Alright, let’s talk poop

    What dose of tirz are you on?
  2. Calm Logic

    Have you noticed Tirz tolerance developing over time?

    There was a Canadian study using continuous glucose monitoring and daily ingestion of maple syrup. But seriously, to me, the sides are a sign that the tirz is still effective later on. For every person on 15 mg of tirz, there may be at least 20 people married to 5 mg because of side effects...
  3. Calm Logic

    Cain @NexaPh comes through

    But what if you have a crush on your middleman and have collected all his merch? :D
  4. Calm Logic

    How long does it take for Reta to start working?

    Haven't tried reta yet. But with tirz, it takes at least 48 hours for the strongest effects for me.
  5. Calm Logic

    Anyone trial >12 mg Reta or stalled on high dose reta?

    I guess maz does relatively well (comparable to survo) despite its least-impressive GLP value since it requires higher doses than survo and the other GLPs. A great point from The Gospel of @Super Trips is that they are all at least decent for stacking with tirz or reta:
  6. Calm Logic

    Cain @NexaPh comes through

    Lots of places have reta for less than $1 per mg now, including single-vial sellers like Grey Axis Research ($40 for 52.78 mg, which is 76 cents per mg). Calculation of cost per mg, based on SSA's China pricelist: ItemCost of 10 VialsCost per mg Retatrutide 5$70$1.40 RT10 $90$0.90 RT12...
  7. Calm Logic

    Cain @NexaPh comes through

    Yes.
  8. Calm Logic

    Cain @NexaPh comes through

    If you don't have $850 to spend on R48, then that says more about you than about Cain. (But to me, the much bigger issue than pricing is his future legal status. If/when the FDA gets serious, they may go after the big fish. Like I said before, who doesn't know about Nexaph?)
  9. Calm Logic

    Cain @NexaPh comes through

    To me, the worst of Nexaph was letting horribly-melted NAD+ out the door, only to offer certain people refunds (and usually only partial refunds, it seemed).
  10. Calm Logic

    When you get scared by stupid SSA staff selling you medical products!!!!!!!

    Another adjustment is Chinese customer service. The attached info on Lipo-C administration mentions subq as the norm, with IM for faster absorption or larger doses. The PDF is from Defy Medical. Most ready-to-inject vials from India will say for IM/IV injection but are often used subq, like...
  11. Calm Logic

    Anyone else receive a Notice of Seizure via certified mail?

    Just India Post, it seems. It was India Post that made their own decision.
  12. Calm Logic

    When you get scared by stupid SSA staff selling you medical products!!!!!!!

    So all this drama over Lipo-C, which is overrated and becoming unpopular, except for maybe the B12: As with B12 by itself, you don't refrigerate it:
  13. Calm Logic

    Your SSA Experience…

    Damn! Meanwhile, people ordering glutathione and other goodies from South Korea get their stuff in three days by FedEx.
  14. Calm Logic

    Recommended supplier

    If there ever was an exit scam, it was the withdrawal of Brute Enforcer Emeritus's constant sunshine 🌞
  15. Calm Logic

    Recommended supplier

    You've just been promoted to Director of Master Pricelist Administration. With this volunteer position, you will be too busy for other hobbies.
  16. Calm Logic

    Recommended supplier

    Uther is still a thing, just never popular here, partly due to their GLP pricing. But it seems they test consistently well third-party and have much better customer service than SSA or SRY (or possibly any other China vendor). They are also known for their nootropics.
  17. Calm Logic

    Anyone trial >12 mg Reta or stalled on high dose reta?

    Someone posted the table above in the survo subforum here. I verified most of the KI values before as being what is in the research literature: https://glp1forum.com/threads/wbs.4706/post-68224 But for survo, all I know for sure is the 8:1 ratio between GLP and glucagon was mentioned in the...
  18. Calm Logic

    From Reta to Survo

    Part of a summary from Google Gemini: In my book, it's another win for reta and tirz, with reta seeming to have more GIP activation than tirz.
  19. Calm Logic

    From Reta to Survo

    To add to your point, GIP is protective against nausea partly by being neutral for gastric emptying: From https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1431292/full?hl=en-US
  20. Calm Logic

    Stacking Tirz with reta?

    At high enough doses without sufficient titration, even reta alone can cause problems, like 24/7 hiccups: https://glp1forum.com/threads/gyc-reta-50-gb.3151/ A potential problem with stacking, without an established protocol, is if you wake up adventurous one morning and inject far more than...
  21. Calm Logic

    Legal concerns if powder delivered to wrong address?

    For GLPs, Google Gemini's answer is as comforting as a warm blanket on a snowy day: ....but if the substance tests as HGH:
  22. Calm Logic

    Legal concerns if powder delivered to wrong address?

    What I wonder about every single day is what happens when USPS/FedEx/UPS delivers to the wrong address, and someone opens the package and sees a bunch of white powder. Obviously not anything usually, but it makes me wonder if any of these wrong addresses call the authorities. I know one can...
  23. Calm Logic

    From Reta to Survo

    Yeah, many tirz users take reta and tirz together while switching to reta. That is a guessing game too, if not more so. While reta is more cost-effective for triple agonism, with more GIP activation and more glucagon activation per mg, reta is clearly not optimized for everyone...
  24. Calm Logic

    From Reta to Survo

    Not a concern for me, nor something I have read. I sometimes use the phenol in my injectable B-12 as an alternative to BAC. So I plan to use B-12 the next time I recon HGH, which can be visibly fragile during and after recon (very prone to foaming and degrades quickly if left out of the fridge...
  25. Calm Logic

    Considering Survodutide

    That reminds me of the theory that people with lower BPs will have greater HR increase.
  26. Calm Logic

    From Reta to Survo

    A new study shows high-dose mazdutide (16 mg) resulted in 21 percent weight loss in 20 weeks. That seems promising for high-dose survo as well, which is being studied at 6 mg.
  27. Calm Logic

    High-Dose Tirz Weight Loss

    Survo(dutide) is a GLP that activates GLP-1 and glucagon. There is a survo subforum here for more info about it. Ghetto reta usually refers to stacking tirz with survo, as the combination hits the same three receptors as reta. Mazdutide with tirz is also seen as ghetto reta for the same reason...
  28. Calm Logic

    High-Dose Tirz Weight Loss

    As you may know, reta is popular among the Meso/bro crowd for maintaining muscle while losing weight. This is because they can eat more on reta. I wouldn't increase the tirz. I would just wait it out longer or stack with survo. The problem with switching to reta is very possible/probable...
  29. Calm Logic

    High-Dose Tirz Weight Loss

    @Blitziod What is you goal weight now?
  30. Calm Logic

    Bac water

    The BAC reseller I use now has a Jotform: https://form.jotform.com/252146441873054 Cost is $12 each plus $8 flat-rate shipping (free shipping for $100 orders).
  31. Calm Logic

    Cain @NexaPh comes through

    Gotta love behavioral economics. The best thing Cain did was becoming well known by everyone. Who hasn't heard of Nexaph, except the remaining employees at the FDA?
  32. Calm Logic

    Cain @NexaPh comes through

    If I was in the UK or other parts of Europe, I would probably use SSA from China. SRY from China would be my other consideration. As the two big China vendors, they generally have the best prices and selection. Uther has higher prices on GLPs but better customer service. So far, I have only...
  33. Calm Logic

    Cain @NexaPh comes through

    Four months later, after prices have gone down for reta everywhere, PGB's R24 is now on "sale" for $10 off. So $390 instead of $400, haha.
  34. Calm Logic

    Your SSA Experience…

    At least in theory, freezing the expandable solution may lower the integrity of the vial, compromising sterility. And though tests may show purity is preserved, that does not rule out unnecessary aggregation.
  35. Calm Logic

    From Reta to Survo

    Right, or stack with cagri instead. The big appeal of survo is stacking with tirz. Survo and tirz would compete for GLP-1, increasing GLP-1 activation. This could result in more weight loss but also more side effects like nausea:
  36. Calm Logic

    IGF-1 LR3 - not seeing much talk here

    On that note, some men are doing subq and don't even know it: from Testosterone Therapy With Subcutaneous Injections: A Safe, Practical, and Reasonable Option But if you have to use IM due to ISR issues with the carrier oil or volume, then the VG (ventrogluteal) muscle area, previously...
  37. Calm Logic

    IGF-1 LR3 - not seeing much talk here

    Another vote for subq: https://swolverine.com/blogs/blog/unlocking-the-power-of-igf-1-lr3-the-ultimate-guide-to-growth-and-recovery Though LR3 is used to target muscle growth (with or without HGH), I'm not in a rush to try it. As Andy was saying, HGH is more comprehensive. And HGH is easier...
  38. Calm Logic

    From Reta to Survo

    A comparison table from a recent article, with the weight loss being faster for the triple-agonist reta (almost 15% weight loss for survo or maz vs. 24.2% for reta). Maz is already approved in China. But most people who use survo or maz do so for stacking, especially with tirz since tirz +...
  39. Calm Logic

    IGF-1 LR3 - not seeing much talk here

    Reconned with that low strength of AA and then administered by adding BAC to the syringe, to lower the pH: https://glp1forum.com/threads/igf-1-lr3-not-seeing-much-talk-here.5110/post-74469
  40. Calm Logic

    From Reta to Survo

    And survo is designed with a 8:1 activity ratio, so eight times more potent for the GLP-1 receptor than for the glucagon receptor. Both reta and tirz are more potent for GIP than anything else. From the TG survo group, regarding dose strengths:
  41. Calm Logic

    From Reta to Survo

    Amino Lair has their survo 10 kit on sale for $200 ($10 less than usual, as well as singles for $30). There are other affordable single-vial resellers of survo like Grey Axis Research, but Grey is currently sold out. There is also a TG community just for survo and maz users. And survo is...
  42. Calm Logic

    From Reta to Survo

    I am on survo now too. I plan to just take it by itself (for a little while at least) to get familiar with it. Just increased the dose to 1 mg this morning. The only side effect I may have experienced at lower doses like 0.3 mg was diarrhea, but that could have been from another GLP. So...
  43. Calm Logic

    IGF-1 LR3 - not seeing much talk here

    One positive for IGF-LR3 is that it is less fragile than HGH, due to its simpler, smaller, engineered structure. HGH is even more fragile than I thought. Six days of reconstituted HGH being outside the fridge resulted in a purity of 59.3 percent. And if there ever was a reason to vent a vial...
  44. Calm Logic

    Tirz - what ones best

  45. Calm Logic

    Tirz - what ones best

    I still get a little nervous sending crypto, which is why I limit myself usually to BTC. BTC is harder to screw up, and I've never had a problem. I love the Exodous wallet. I have even used it (with USDC stablecoin) to pay for groceries and other shopping trips (by using the Exodus virtual...
  46. Calm Logic

    Tirz - what ones best

    GYC was (and still is) popular among the smaller vendors (i.e. not SRY or SSA), including among single-vial resellers who resell GYC. They went down (literally) when the law was on their tail. So when they came back, I guess they lost some popularity from being absent for a while, and people...
  47. Calm Logic

    Average costing tirz ,years worth

    With R-50, for example, GYC's US warehouse wants $385 for one kit. So buying 10 kits only saves $35 a kit, which does add up though to $350. But I don't know if they would negotiate down from that, especially for "just" 10 kits. 50 kits (or at least 25 kits?) is where the action seems to...
  48. Calm Logic

    Average costing tirz ,years worth

    I assume significant bulk buying is involved to really negotiate, unless one is doing something more like price matching. GYC's US warehouse, for example: T-20 10kits+ $95 50kits+ $80 T-30 10kits+ $125 50kits+ $100 T-60 10kits+ $220 50kits+ $200 R-30 10kits+ $240 50kits+ $220 R-50...
  49. Calm Logic

    IGF-1 LR3 - not seeing much talk here

    I have no complaints about HGH either, especially given its synergy with AAS. HGH just seems fragile compared to GLPs and other peptides. Like fragile enough that some on Meso may rightly be saying that filtering it may cause unnecessary mechanical stress, leading to aggregation. I don't...
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