GLP-1 Forum

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  1. hexagonal

    GYC Tirz60 and Reta30

    No. It just means that there was enough force exerted on the vial to cause the puck to split.
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    Presidential Change - Effects on Acquiring Peps?

    CBP is moving to put in a lot of new fancy machines to scan stuff and in theory get better at catching incoming drugs, etc. They're probably more focused on opioids, but my understanding is there's no real cost to them loading up the signature scanning with the signatures of pretty much...
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    Tracy gone MIA?

    There is significantly less risk in moderate usage of AAS than extremely high levels, to be sure. But there is increased risk even at trt+ levels. You want to minimize it watching your bloods, bp, etc., for sure. But it's still more than if you weren't doing it. I've got no issue with people...
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    USA Domestic Source / Shipping

    It's a little strange I don't know if it's "standard", but it's certainly quite common. Plenty of people filter their peptides, and there would be no point in putting them back in the original vial which contains any potential contaminants that you removed by filtering Filtering your peptides...
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    Tracy gone MIA?

    It's well known that some people tolerate steroids better than others. IFBB pros exist and most of them don't fall over dead. I'm legitimately glad for you that you respond well and that it has minimal impacts on your blood pressure. That isn't the case for everyone, even those that are at...
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    Tracy gone MIA?

    Something being decriminalized means very little for the safety profile of use. It's perfect legal to eat and drink nothing but hamburgers and soda, but it's still awful for you. Alcohol is legal in most of the world, heavy use of it is still awful for you. Abusing a drug, again, in the...
  7. hexagonal

    Tracy gone MIA?

    I'm sure zpped and I will do our best to revert this progress the next time we go off on a tangent in some random thread.
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    Tracy gone MIA?

    This is unrelated to that.
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    Tracy gone MIA?

    When talking about "abuse" in a medical context this basically means outside of prescription/medical supervision and beyond the therapeutic doses the medications were developed for.
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    Tracy gone MIA?

    Whomever told you that AAS do not act on neurotransmitters is incorrect: https://www.sciencedirect.com/science/article/abs/pii/S0924977X12001095 There's also a wide variety of other potential causes - AAS use impacts your brain in a lot of ways...
  11. hexagonal

    Tracy gone MIA?

    People like being self-important and part of an "in crowd" that knows things, and showing off that they know things. Doubtlessly, I'm no exception to this either.
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    Tracy gone MIA?

    I don't think I'm better than AAS users, but AAS are psychoactive substances, some potently so. I'm quite likely to be an AAS user if I can get all of my bloodwork, blood pressure, etc. under control as I get down to my goal weight and bf%, but I recognize that I will likely have to make...
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    Tracy gone MIA?

    QSC Meso thread is entertaining. People going on about exit scams, people posting cryptic messages about the "real" reason QSC is going through whatever this is and how you had to have been a member for a long time to know, people fearmongering about US customs becoming an impenetrable shield...
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    Ruder, At ObesityWeek, More Data and Questions About Semaglutide, Tirzepatide, and Retatrutide (2024) 331(1) JAMA 9

    That's not what I'm talking about, though. It isn't about whether or not long-term adherence to lifestyle intervention is effective in the broader population - we certainly know it isn't - but most studies do track adherence to lifestyle interventions, otherwise you can't be sure if you're...
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    Ruder, At ObesityWeek, More Data and Questions About Semaglutide, Tirzepatide, and Retatrutide (2024) 331(1) JAMA 9

    Interesting. I'm curious how adherence for the lifestyle intervention people is? Lifting doesn't seem to impact the number on the scale too much (Hopefully in part because I'm adding some muscle mass...), but the weeks when I'm better about diet, cardio, or both, I definitely see more progress...
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    Here is an article comparing the different weight loss medicines

    You made a strong statement about how the way a good portion of the users of retatrutide are doing it wrong without providing any evidence. I'm not sure how you think that's not making an argument. If this was a private conversation, I'd shrug, wonder why someone believed that, and ignore it...
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    Ok, I’m bored. And semi addicted. What’s next?

    Yep! Edit: 3ml, rather.
  18. hexagonal

    Here is an article comparing the different weight loss medicines

    I am making a claim that we have no specific reason to believe that twice a week is less effective than once a week. For someone who is passing judgment on people's adherence to scientific principles, you should probably remember that the null hypothesis is a foundational part to science. At...
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    Ok, I’m bored. And semi addicted. What’s next?

    I recon multiple vials for most of my use as pens. Recon 2 vials, draw into syringe, filter into cartridge. I'll be set up to do a few pens at once and use one pen needle to purge the air. Plenty fast for me.
  20. hexagonal

    Here is an article comparing the different weight loss medicines

    I'm not the one making strong claims about the efficacy of weekly dosing vs. more frequent. But we can look at what we know in other medications and extrapolate from there. We tend to find more frequent dosing performs as well as longer dosing, and sometimes better...
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    Here is an article comparing the different weight loss medicines

    So what you're saying is you can't link anything? And anecdotal opinions aren't worth much. In god we trust, all other must provide data.
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    Here is an article comparing the different weight loss medicines

    I've not seen anything like that in any of the papers on the reta trials that I have read. Can you link them?
  23. hexagonal

    Here is an article comparing the different weight loss medicines

    So... if you dose once a week and the ketogenic effects are only there at the start, then you don't get them for the rest of the week? By that logic you should be dosing more frequently at levels that keep it high enough to cause the ketogenic impact. But the idea that ketogenic effects are a...
  24. hexagonal

    Here is an article comparing the different weight loss medicines

    Plenty of people get great results dosing twice a week on reta. For me the heart rate side effects are too high to do weekly, too.
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    Has anyone tried HGH???

    I've never heard of it not stopping. I put on about 8lb on ipa/tesa boosting my IGF-1 up to the 350s, finished up that cycle last Friday, and I've already lost 4lb of it.
  26. hexagonal

    Has anyone tried HGH???

    Water retention is a common side effect for anyone using enough to go above replacement level. That dosage will depend on you, your current HGH/IGF-1 levels, and how you respond to exogenous GH. From anecdotal reports I've seen, replacement level for most people seems to be about 1-2IU/day
  27. hexagonal

    Has anyone tried HGH???

    Were you experiencing any actual issues from the water retention or just worried about the weight on the scale? Some people do experience some actual issues with water retention, such as carpal tunnel, etc. But if you're not, I personally would avoid the diuretic. Adds a bunch of other...
  28. hexagonal

    Has anyone tried HGH???

    Prices on most everything out of China is significantly lower than the prices for the same item sourced domestically. But HGH is a controlled substance. You're playing with fire importing it in a way you aren't with the non-controlled peptides.
  29. hexagonal

    Here is an article comparing the different weight loss medicines

    The glucagon receptor activity results in an increase to base metabolism. But plenty of people experience appetite suppression with reta, just less of it than with some other glp1s.
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    help me choose a pep to round out an order

    I personally would hold TB-500 (and BPC-157) for when you have an actual injury. Both are known to promote angiogenesis, which is good when you have an injury, but bad if you happen to have a tumor growing somewhere. There's also some correlations in studies with TB-500 and cancer metastasizing...
  31. hexagonal

    Is there any advantage to joining vendor discords and telegrams?

    I wish mine hadn't. I became a weeb more than 30 years ago, before I knew what a was a terminal illness is was.
  32. hexagonal

    Is there any advantage to joining vendor discords and telegrams?

    Because you decided to be pedantic about my use of cartoons to mean western animation when someone said they didn't know the difference between anime and manga. "I don't know why we're talking about something" doesn't work well when you're the person that spawned the thread of conversation...
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    Is there any advantage to joining vendor discords and telegrams?

    I've Returned To My Past As A Secretary For My CEO Boss Who Was Once A Cold Duke Of The North Who Needs To Marry Me Under Contract
  34. hexagonal

    Is there any advantage to joining vendor discords and telegrams?

    anime and manga are mutually exclusive terms comics and cartoons are hierarchically inclusive terms
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    Is there any advantage to joining vendor discords and telegrams?

    The colloquial use of cartoons heavily implies animation and should be even more readily apparent in context. When someone talks about enjoying their saturday morning cartoons, they're not pulling out the newspaper and reading the funnies.
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    Is there any advantage to joining vendor discords and telegrams?

    Manga is to comics as anime is to cartoons
  37. hexagonal

    No results after second shot

    Everyone that got 0 peptides got a whole batch of 0 peptides. There have been no reports of one vial containing a peptide and another vial containing none. On the other hand, there are tens of thousands of people reporting feeling like any given dose did nothing even when on name brand. And we...
  38. hexagonal

    BAM-15 new mitochondrial uncoupling agent

    There's a whole host of things in the range between "safer than DNP" and "I still wouldn't touch it with a 10 foot pole." Any sort of uncoupler that hasn't gone through EXTENSIVE lab trials is in that range.
  39. hexagonal

    GYC shipping vials with zero peptides detected

    Shit, I've got some ASC vials I've injected that didn't even have that.
  40. hexagonal

    Is there any advantage to joining vendor discords and telegrams?

    I recognize Inuyasha and Mars out of all of those.
  41. hexagonal

    Is there any advantage to joining vendor discords and telegrams?

    Join the rest of us in being a jerk. You can spend even more time online and raise your blood pressure!
  42. hexagonal

    8 Week Ipa/Tesa Stack Bloodwork

    Yeah, I was below 200 on multiple tests before TRT. It's been a huge QOL improvement going on it.
  43. hexagonal

    8 Week Ipa/Tesa Stack Bloodwork

    Not sure if it will bump test any, but I'm on TRT, sitting around mid 700s total, 25 free.
  44. hexagonal

    AAS / steroids - Do all vendors usually carry them?

    kits4less is on here as well in the vendor forum. but yeah, better for meso/steroidsourcetalk than here
  45. hexagonal

    Reconstituting agent for Cagrilintide

    I don't know how applicable the oral semaglutide formulation is, but I'll accept it as being 1:1 for the sake of argument. Except that they explicitly say that Cagri does not meet their design thresholds at the 7.5 pH, much less 8. If it did, why would they have bothered developing the dual...
  46. hexagonal

    FDA Registered Manufacturers of Tirz API

    Sure, but the peptide itself should either be it or not. We're likely on the acetate salt versions, but unless we think the buffer in the name brand stuff is significantly different and somehow has an impact on the efficacy vs. ours, it should only be down to the differences from the acetate...
  47. hexagonal

    Curious about Chinese vendors incredible shipping times...

    When I've tracked my ASC and QSC orders I can see them moving across China from city to city, watch customs clearance on both sides, etc.
  48. hexagonal

    8 Week Ipa/Tesa Stack Bloodwork

    Will have to wait for the DEXA in a few weeks to see what, if any, impact it had on visceral fat and muscle growth, but: .300mgish of ipa, 2mg of tesa nightly after 2+ hours of fasting, 5 days on, 2 days off. Glucose increased from 92 to 105 (Slightly out of range) Insulin increased from to...
  49. hexagonal

    yet another scam from Tracy at QSC!

    Here's what I get out of ordering from QSC: 1) A vendor with a ton of 3P tests due to the sheer amount of people that order from them 2) Good pricing 3) A large library of stuff to order And... all I have to do is be willing to wait a while for it to arrive.
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