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One of the small handful of things I totally avoid. It just makes me feel like doing more of it.

Sure. Not claiming that she is claiming to be anything else, either. I think adding an active pharmaceutical ingredient to reduce PIP is kind of insane, particularly when you can just dilute it more for the same effect. Especially when she acknowledges the potential cancer growth concerns with...

HGH is significantly more difficult to synthesize than most of the other peptides we deal with on here, and is synthesized using a totally different process. It's molecular structure is 3D, folded with disulfate bonds Most of the ones we get from the grey market are made using a purely chemical...

There's no particular reason to believe that Anela has any real understanding of what she is talking about, and plenty that she doesn't. Anyone can put together a peptide blend and talk it up on social media. I wouldn't suggest a 5 day on 2 day off schedule either, but the idea that doing so...

Looks like the MHRA Yellow Card program is about the same as VARS in the USA when it comes to reporting requirements - literally anyone can make the report. They don't have to be any sort of medical professional at all, much less a coroner/medical examiner/foresenic pathologist/similar. My...

TRT or close-ish to TRT levels. The dose that bodybuilders go down to when not "blasting"/being "on cycle" at higher doses.

1) Sounds good. One thing to keep in mind for time saving is that you generally just need to warm up the muscle once per session - if you're doing multiple lifts hitting the same muscles, there's not as much need to warm up each individual lift, since the muscles are already warm. 2/3) This is...

I mean, I've explicitly raised the topic of female TRT in this thread, so I'm certainly aware. If we're talking ng/dl, quest and labcorp have the top of range for test for adult women at 45/64 respectively, so at 100 you're quite a bit above reference range and I do suspect that extended use...

More sets. Rep ranges are more about optimizing across a few different factors. Basically, your rep range you should be one that lets you accurately gauge how close you to are to local muscular failure, gets you to local muscular failure without overly fatiguing you in other ways or getting you...

You can go to failure safely with free weights as well without a spotter, it just requires proper setup. Dumbbells you basically just have to learn how to drop. Barbells you just need a physical spotter rather than a person. I prefer rack mounted safety straps when I use them since you can...

Mentzer was right in that training close to failure with low volume will still induce hypertrophy, and for some people low volume might work better, but the overwhelming majority of people respond better to higher volume, and the science on this is incredibly clear. There are diminishing...

I do not believe pro sports are clean - particularly since I am aware of how easy it is to get around bloodtests. I fully believe ~100% of pro athletes are on PEDs in the MLB, NFL, etc. For the majority of anabolics, virilization is a significant and very noticeable concern for women. For those...

Meanwhile in my state, places with active complaints and warnings will go 12+ months before they even follow back up to see if things were resolved after the initial warning.

The person you are quoting quite explicitly did call him a shill - he claimed he had a vested interest in us believing in the pharma industry. I was also speaking of a specific vaccine - the science is consistent that the covid vaccines, including the mrna versions, were safe and efficacious...

It's still silly to accuse a longstanding member of being an industry shill, particularly right after he points out that pharma tested as less pure than the Chinese underground stuff. Not exactly the sort of thing an industry shill is going to want to point out. As for the vaccines, I could...

I basically only talk about this stuff on the internet and with my friends who I lift with, so I don't think so! Unless you were in my garage gym a couple of hours ago.

YYF is very far from an industry shill lol

The good news is that even if you lost a lot of muscle while dieting down, getting it back is significantly easier than gaining it the first time. There's still some debate on all the specific mechanisms around it (Satellite cells being deposited and sticking around being one of the leading...

Assume sterility is a fail. Testing one vial tells you nothing about how sterile another vial is, and it fails regularly enough that long-term use guarantees that you will receive unsterile vials. Filtering will handle sterility concerns. If it's a question that would be relevant to everyone...

LPS / Heavy Metals - Jano says he has basically never seen these reach harmful levels Sterility - 3-5% of all peptide vials fail sterility checks (Always filter) Personally, I am confident enough to purchase based on purity tests and assume LPS/Heavy Metals are good and Sterility is bad.

Plenty of people talk KLOW/GLOW for benefits beyond just skin - it's quite popular among bodybuilders. You can't take just GHK-Cu/KPV to replicate all the benefits of KLOW without also adding the BPC/TB, which is my point. Regardless of why they were added by some random person to begin with...

Jano has said ~5% of peptide vials fail sterility tests. One of the reasons I always filter.

Minimal to no solid science behind their claims. We just have basically no studies supporting most of what they say this stuff does. We'll see mechanistic studies in animals held up as a reason (but look at how that turned out for AOD), some reported anecdotes, etc., but most of the effects they...

Family members and friends are notorious for blaming random shit that happened temporally close to the death for what happened even when there is no specific reason to believe it was the case. Is it possible it is related? Sure. Do we have any specific evidence here that it was? Nope. But if...

Jano has tested freezing tirz and it was largely fine. Other peptides have seen significant impact. I don't know if reta has been tested, but without having specific knowledge, I'd personally opt to not freeze it.

Realistically, we have nothing but anecdotal reports on what happens with stacking. We don't know the long term impact and risks, if any. Other glucagon agonist drugs (NN1177) have failed trials due to safety concerns - it's possible the ratio is important to keeping them safe. I personally am...

Thanks for the testing. There's some discussion over on meso that TB frag might be more desirable for most use cases than the full peptide, with the argument being that the fragment is responsible for the benefits we are after, so mg per mg we get more of the useful stuff with frag than we...

I know someone using iamhrt for it. Think there are some subreddits dedicated to female trt that probably know a lot more than I do. SteroidSourceTalk and MesoRX both have some sources that sell lower concentration injectables for women. Lots more to juggle with this side of things, though -...

No one likes being proved wrong :). And I'm just some asshole on the internet - I might not be right! I will say honestly my intention is not to dump on people or win internet points - I just want to make sure we're all looking at all the best information we can so that we have the best chance...

I think this is actually a really important point. Doing any amount of regular exercise - even if it's just half an hour a week - when you were previously doing none? That's an improvement. It will make you healthier. Waiting on a perfect program and doing nothing is just a recipe for staying...

Tirz made it impossible for me to eat enough food to hit my macros - it 100% would have prevented the behavior described. Reta, if I want to eat, I can eat. It doesn't do a whole lot for my physical hunger, either - but that's not what has gotten to me. I'd eat... just because. Think about...

The good news is, you're probably not missing out on anything, re: Machines! https://pubmed.ncbi.nlm.nih.gov/37582807/ Going to failure is still beneficial in that some studies have looked at how good we are at estimating how close to failure we are, and while the answer is "better than you...

None of us should be interested in podcast appearances and similar for anything more than entertainment value and to potentially point us towards things to learn about - we want actual science. People go on Huberman and say all sorts of nonsense all the time, same thing with Attia, etc. Random...

What biological mechanism do you believe happens with older women that causes them to stop responding to muscle growth stimulus the same way everyone else does at all stages of their life? We don't see other significant hormone changes resulting in different muscle growth stimulus being required...

When access to affordable, hyper-palatable, calorie dense food becomes widespread, people get fat. We see it time and time again as countries reach higher levels of wealth and there is greater access to global markets which has this food in abundance, obesity rates start to climb. There's a...

Which would be... not KLOW, which is what this thread is about. The blend in discussion contains these by definition.

We have good studies comparing men vs. women and they are pretty conclusive that women and men respond the same to training. Men make larger gains in absolute terms, but the relative improvement from baseline to finish is very similar. https://pmc.ncbi.nlm.nih.gov/articles/PMC11869894/...

Basically no professional who isn't already indoctrinated into the SS ecosystem recommends starting strength to anyone anymore - even if you want to focus on compound movements, it's just not a well put together program. Elite high school programs moved on, people training adults moved on, etc...

Mine went up pretty quick on both and then just stayed at that same level. Nearly a year in on reta now and my RHR never decreased from it either. Oh well.

It depends on a whole lot. I've totally changed my lifestyle while on tirz and then reta. I doubt that even if I dropped off I'd ever get back to where I was. It's just a lot harder to put on all that fat when you've changed your source of food from Uber Eats twice a day to prepackaged...

I don't disagree that we should care about lead exposure from other areas - of course we should. But if that's the takeaway message, the protein powder manufacturers should just make that the message instead of lying about things like Momentus is doing. I ingest a lot of extra protein - I...

Momentus appears to be lying their ass off based on everything I can find. It is not hundreds of times stricter than the WHO/FDA/EFSA. The WHO withdrew their limits and now emphasizes there is no known safe level of exposure, as does the FDA and EFSA (though they still have some limits). The...

I guess I'm assuming people would be getting most of their protein from meat sources, which I suppose is not a fair assumption since a lot of the concern is specifically with plant protein - they probably were opting for it due to dietary restrictions that would preclude them eating a bunch of...

There is no evidence AOD does anything of use in humans. https://www.abc.net.au/science/articles/2013/07/26/3811053.htm It was abandoned for weight loss because it did nothing. They started trials on it for osteoarthritis, but they never reached human trials and the last published study I've...

I used to be a big Starting Strength proponent, and it's what I got my start on, but I'd recommend against it these days, and particularly against it for most of the people here for weight loss. It's a program that is focused on a multiple decades old understanding of exercise science and...

Glad CR is doing the testing. They're not the first to call out plant protein as being particularly bad here - clean labels found a nearly 3x increase in being over the lead limit in plant based products https://cleanlabelproject.org/protein-study-2-0/ - and stuff labeled as "organic" was...

I still enjoy all of my vices and have not quit any of them. I partake in them far (far) more infrequently, though.

Purity testing over 99% says nothing about contaminants, sterility, etc. The vast majority of material in the vial is excipients and not the API we care about. It's just about how degraded or not the API is. Something might fall behind a shelf in a hot warehouse and get discovered years later...

Yep, I have a coffee mug warmer I use. Put the vials on it before I get in the shower and they're good to go by the time I've showered and dried off.

Was in a rush when I posted this and forgot to come back and tell the full story here but wanted to post a warning. I had a pretty significant reaction to them myself - using the braun inline filter ones. I had a series of 4 sterile abscesses that I strongly suspect was caused by the plastic...