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The article is not paywalled, but it's close: When I opened it in my incognito tab, it required that I set up a free Washington Post account where they'd send me spam to encourage me to join. Try this: Gilbert2.pdf. I printed out a .pdf of the same article.

The approaches used in the trials are not set in stone. Nor is the advice given by the FDA approved instructions as to dose to be applied religiously. I'm not sure that our actual approach is that different.

I use a quite unconventional dosing schedule. For most folks, it's overly complicated. I use an Excel sheet I found on Peppys that calculates how much mazdutide I have in the body. That figure is on the right. The figure on the left is how much I inject each day. As you can see, I ignore the...

If you read jellybelly54's post, he (or she) suggests that he followed the links from Alice's official vendor page. "So I thought this would be a good place to order my first order of peptides. Clicked on the links underneath the vendor. Took me to the discord page. Started a communication with...

Gilbert is the last name of the author.

Reta is fine but it creates problems with some people. Both semaglutide and tirzepatide created problems for some folks too. I personally use mazdutide. I'm not going to tell you whether it works for me or not because I started just a few weeks ago.

I am definitely not a fan of Donald Trump. However, this looks quite good so far, with the government pressuring two big drug companies to lower prices with assurances, I suspect, that far more people will be using the drugs. The drug companies still make large amounts of money -- as they...

Gilbert (Nov. 7, 2025). What you need to know about Medicare coverage for weight-loss drugs - Experts call President Donald Trump’s deal with drug companies a breakthrough, but details of how it will work are still emerging. Washington Post, paywall-free link: https://wapo.st/3WGwP87

Considering my success I also see little reason to stop. I was unable to lose much weight without these drugs and even the weight I lost I was unable to keep off.

See also Hsia, et al (poster presentation, Obesity Week 2025). Eloralintide Phase 2 Study in Adult Participants With Overweight or Obesity - Design and Study Population...

In this 48 week study, mazdutide was given in different dosages. The study lasted 48 weeks. People who took 16 milligrams of mazdutide lost slightly over twice as much weight as those taking only six milligrams. Granted the people taking six milligrams actually spent the majority of their time...

She is a legitimate vendor. By that, I mean she has fulfilled purchases before. I do note that she promises to reship stuff if you have customs problems. I don't actually understand her message. Ask for clarification. But I wouldn't send any additional money to her other than for a new order...

@ZippityDooDah Maybe it's time to create a new category for eloralintide. It's an amylin-based weight loss drug. Right now, most weight loss drugs are what are referred to as GLP-1 drugs, including drugs that only work on the GLP-1 system and drugs that also work on the glucagon and/or GIP...

I had never considered that something like this would help folks lose weight. Singh, et al. (2025). Duodenal Mucosal Resurfacing Stabilizes Weight Loss After Glucagon-Like Peptide 1 Receptor Agonist Withdrawal. Poster at Obesity Week 2025...

The farther one deviates from the conditions in a study, the less likely the results in the study will apply to that person. I agree that individual outcomes different from group outcomes. So are group outcomes irrelevant? Not at all. If a drug was tested in a large group and in general...

I actually don't remember. I remember when I looked up what to do, it looked quite complicated.

I'd also be willing to use my Hospira water past 2036. As a practical matter, although I have over a case of Hospira water right now, it won't be around then. I'll either have used up my BAC water reconstituting peptides within a few years of now or I'll have thrown away the BAC water. I'm...

The official answer is that once a vial of BAC water has been punctured, it should be used with 28 days. After that, it should be discarded. However, that advice is given for hospital settings, where there are often multiple patients and tons of germs around. Most folks who use BAC water for...

The Chinese manufacturers also believe in having high standards. Just state what standard that you want them to meet and they'll assure you that they're complying with it.

Here is an updated list, part II: List of Reta Sources Tewari, et al. (2025). Efficacy and safety of triple hormone receptor agonist retatrutide for the management of obesity - a systematic review and meta-analysis. Expert Rev. Clin. Pharmacology, 1–16, doi.org/10.1080/17512433.2025.2450254...

Here is an updated list, part III: List of Reta Sources Martins, et al. (2024). Glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide agonists for the treatment of obesity and diabetes mellitus. Exploration Drug Sci., 2, 126-143, doi.org/10.37349/eds.2024.00039. Melson, et...

Here is an updated list, part II: List of Reta Sources Hong & Choi (2024). Gut Hormones and appetite regulation. Curr. Opn. Endocrinology Diabetes & Obesity 31(3), 115-121. Jastreboff, A. M., Kaplan, L. M., Frías, J. P., Wu, Q., Du, Y., Gurbuz, S., Coskun, T., Haupt, A., Milicevic, Z., &...

Here is an updated list, part I: List of Reta Sources Abouelmagd, et al. (2025). Efficacy and safety of retatrutide, a novel GLP-1, GIP, and glucagon receptor agonist for obesity treatment - a systematic review and meta-analysis of randomized controlled trials. Baylor Univ. Med. Ctr...

You wrote the best, in my opinion, that appears in the thread. However, based upon the screenshot posted by @frankpeptid, it appears one has request the additional names on the CA when placing the order with Janoshik. https://glp1forum.com/attachments/unnamed-png.9520/

Only 99%. Where does the other 1% come from?

You can find the US manufacturers right next to the unicorns.

At best, Nexaph lyophilizes the peptides here. But Cain has a history of lies. I'm not criticizing Nexaph product or customer service.

I haven't taken survodutide. I'd be reluctant to take it because it is less well studied than the FDA approved drugs and reta. Also it seems to carry more side effects than the other weight loss drugs. It seems like it will turn out to be reasonably effectively, probably stronger than...

I'm glad that you'll use them. I know that most folks, certainly including me, it is hard to read and understand the scientific articles. I'm much better and finding and getting copies, when necessary, of the studies than at being able to interpret them. It was easier compiling something on...

Arun, et al. (pre-publication, 2025). Survodutide- A Dual GLP-1 - Glucagon Agonist Reshaping Cardiometabolic Care. Cardiology Rev., https://doi.org/10.1097/crd.0000000000001062. Awad, et al. (2025). Evaluating the efficacy and safety of survodutide for obesity - a systematic review and...

I can imagine the report to the FDA: "I bought GLP-1 from a vendor called Homopeptide and ever since I purchased that vial, I've been having gay sex twice a day. But I'm not gay. Really. I'm not that type of person."

I don't worry about situations like that since I know that my farts smell great.

Is there a reason that you're not waiting to see if a higher dose of tirz will work better?

Stablecoins are good idea for another reason: If you are a US citizen, you are required to file a tax return (1) stating whether you owned or used crypto in the last year and (2) showing any interest that you earned from crypto. The real problem, at least for me, is not paying those taxes...

Here is a paywall-free link to the article that appear in the British Medical Journal on GLP-1 deaths in the UK: Iacobucci (2025). GLP-1 agonists - 82 deaths linked to adverse reactions, UK data show. Brit. Med. J. 388, r390...

I intended on replying with an AI photo of a dinosaur scrotum to this post: https://glp1forum.com/threads/is-your-arse-still-there.6537/post-80791. Further research led me to the conclusion that humans do not know whether male dinosaurs had scrotums.

Good. I had not originally noticed that it took five months before they went to the press. I also note that this appears to be a story pushed by the daughters as opposed to someone from the UK government warning of the dangers. I read that someone was arrested in connection to the death for...

ChatGPT can be amazing in finding good answers. However, when I asked it to prepare a chart of 5 peptides to see how much they activate GLP-1, GIPR, and GCGR, ChatGPT provided right information as to four peptides but wrong information as to survodutide. (The chart with the black background...

I'm an attorney. I remember a friend asking if I would recommend a medical malpractice attorney to sue a doctor because her friend's mother died supposedly due to medical malpractice. Before I could decide upon an attorney to recommend, I learned that the autopsy showed that the mother OD'd on...

It seems premature to blame to the death on what was injected into her (even if the wrong weight loss drug) before hearing the opinion of the pathologists.

I messed up on the Lau, et al., hyperlink. That won't allow you full-text access without seeing a paywall. Use this link for Lau, et al.

The chart is figure 2 from Chao, et al. (2025). Evolving Approaches for Pharmacological Therapy of Obesity. Ann. Rev. Pharmacol. & Toxicol (65), 169-189.

I believe you obtained that table from ChatGPT since I obtained a table that had the same numbers and looked the same from ChatGPT. I believe the numbers are wrong as to survodutide. I couldn't find sources backing up the numbers that ChatGPT offered. Instead, this is what I found: "When the...

I botched the hyperlink for semaglutide. It led the doi, but did not lead to a paywall free article. I fixed that. Comparative Binding Affinities.pdf. Here is the link to the article: Lau, et al. (2015). Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide...

The studies were conducted in vitro using human GLP-1 receptors.

I had seen the chart before but I had discounted the likelihood of it being accurate after I did a Google search for it. While I found the chart shown elsewhere, I didn't find it cited in any sources that I consider reliable. By reliable, I mean with references to scholarly stuff. Therefore, I...

About 20-25 years ago when I used the internet, I thought to myself that if the scammers weren't so dumb and didn't make so many mistakes, it would be quite easy to get scammed. Now the scammers have gotten good.

I saw a chart repeatedly showing the supposed potencies of different weight loss drugs in humans. I assumed that the information in it was wrong, but when I checked, everything matched scholarly sources. The profiled drugs are semaglutide, tirzepatide, retatrutide, mazdutide, and survodutide...

I can now confirm the accuracy of all figures in this chart, by which I mean that the figures match those that appear in peer-reviewed journals: Sema: Lau, et al. (2015). Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide. J. Med. Chem. 58(18), 7370...