I see people claim both. Mostly the fat shamers saying you need to stop, and the people who have been fat shamed claiming they will lose effectiveness/you'll regain everything if you go down/stop. It's a socially/emotionally loaded topic that makes having real discussions about it difficult, unfortunately.
I was hoping there were enough rational people on this forum to have actual discussions without pearl clutching and false assumptions. As much as I see people trash talk bodybuilders for being “meat heads”, they tend to be the most open to new research and experimentation, even those who have struggled with obesity in the past.
I have had spinal meningitis twice in my life and after transphenoidal surgery in 2022, I am sure that the IV antibiotics wiped out a good portion. I eat very well, take an adequate amount of supplements, work out rigorously a few times a week but I know it’s not enough to reverse the effects. I am near Rice University where they pioneered fecal matter transplants but I didn’t qualify for any of the trials. If I didn’t actually work in the industry, I probably wouldn’t be doing as well as I am. :/
I was wondering..since you seem to have a lot of treatments covered without hassle. No way anyone with my insurance provider would get glps prescribed for lack of a certain probiotic..Severely obese people here have a hard time. You are very lucky in that sense. But you seem to have had a rough road health wise, and I am very sorry you have suffered. Gut bugs are so important we now know.. But it's true that replacing them isnt as easy as you'd think.
I wouldn’t say “lucky” so much as I chose to move my career in a direction that would support my health. I moved from Los Angeles to Houston to be near the biggest medical center specifically so that I could have access to some of the top research clinics. 👍
In other news, 49% gain all their weight and more back. 😂According to the records of 40,000 patients at Epic, more than 50% of them were able to keep off the weight or continue to lose weight in the 2 years after discontinuation of GLP-1’s. Roughly 20% gained the weight back. This is based on medical records, not self-reported. Regardless of how many studies or reports come out, I still hear people parrot the narrative of Big Pharma that “once you pop, you can’t stop”. I get this may be the case for opioids, but GLP-1’s seem to affect different people differently.
View attachment 9969
Two Years After Stopping GLP-1s, Most Patients Sustain at Least Some Weight Loss
Facilitating rapid sharing of new medical knowledgewww.epicresearch.org
pmc.ncbi.nlm.nih.gov
Feel free to send as many links as you want. I found out today my doctor is in South America for another week. I’ll call back next week and see if one of the other doctors can give me a straight answer, at the latest I’ll know the first week of December.This paper shows great promise with Akkermancia.. Supplements do seem to work.
High fat diet kills it though. All kinds of positive news in here.
Strategies to promote abundance of Akkermansia muciniphila, an emerging probiotics in the gut, evidence from dietary intervention studies - PMC
Akkermansia muciniphila is a mucin-degrading bacterium commonly found in human gut. A. muciniphila has been inversely associated with obesity, diabetes, inflammation, and metabolic disorders. Due to its highly promising probiotic activities against ...
As long as the patient's new medication collection is recorded in Epic's EHR then it will record the medication switch and count them as continuing to take a GLP-1. But this assumes the patient's prescriber and pharmacy all continue to use Epic's EHR. Little pedantic but thought I'd clarify
I see people in the community all the time talking about hitting goal weight and slowly dropping dosage until they are off. Some do lower doses not even weekly anymore. Some are like me and the insane cravings like my body wants to jump back where it always goes after I lose weight when I lower my goal weight dosage. I really haven't seen any sector of this community be all or nothing as far as "YOU MUST STAY ON BECAUSE I HAVE TO" or "You have to get off as soon as you can because its not good long term.
I'm in maintenance, dropped dosage significantly, and enjoying food lol. I've started trail running again (I was really breaking my back trail running at 240 lbs!), so as long as my clothes still fit, I'll slowly titrate down. Like with any medication, I want to be on no or the lowest possible dose long term. But I'm also coming to this space from not being obese for most of my life so maybe I'm a little more confident than some?
I don't really see a whole lot of that kind of black-and-white talk outside of reddit. I think once you've graduated to here and other "advanced" spaces in the online peptide world, there's a lot more people capable of nuance. Which is why I keep my participation in the reddit peptide subs at a minimum.
