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Lullabytreehugger

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I am not sure if you realise it or not but your vial sizes are too small.

Allow me to explain. I currently stack 3 peptides.

7.5mg tirz (once a week)
8mg reta (4mg twice a week)
2mg sema (1mg twice a week)

Now with the current size vials that most suppliers sell lets do the maths.

30mg vial tirz = i only get 4 doses from a vial
20mg vial reta = i only get 2.5 doses from a vial
10mg sema = i only get 5 doses

Why are you guys not increasing your vial sizes?

I think tirz should be a min 60mg vial
Reta should also be 60mg vial
Sema should be min 50mg vial

Let’s not mention cagri or motsc etc.

Sure the small vials like 10mg sizes are great as a sample but not for long term use.

This stack works for me the best. I have tried with different amounts and different split doses but this works the best for me.

Sema helps with food noise and appetite. Tirz keeps my glucose levels in check. Reta to bring down my weight.
 
I have a kit of smaller vial tirz (15mg). So what I've been doing is just recon two at a time and when I filter it I put both into a new sterile vial. I suppose if you're not filtering it's extra work though. I'm only 3 months in and nowhere near the max dose though.
 
I am not sure if you realise it or not but your vial sizes are too small.

Allow me to explain. I currently stack 3 peptides.

7.5mg tirz (once a week)
8mg reta (4mg twice a week)
2mg sema (1mg twice a week)

Now with the current size vials that most suppliers sell lets do the maths.

30mg vial tirz = i only get 4 doses from a vial
20mg vial reta = i only get 2.5 doses from a vial
10mg sema = i only get 5 doses

Why are you guys not increasing your vial sizes?

I think tirz should be a min 60mg vial
Reta should also be 60mg vial
Sema should be min 50mg vial

Let’s not mention cagri or motsc etc.

Sure the small vials like 10mg sizes are great as a sample but not for long term use.

This stack works for me the best. I have tried with different amounts and different split doses but this works the best for me.

Sema helps with food noise and appetite. Tirz keeps my glucose levels in check. Reta to bring down my weight.
That seems crazy to use that much. I hope long term you will be ok. T definitely comes 60mg vials. In the long run though I think less contamination is key if you have to open more vials for often.
 
I have a kit of smaller vial tirz (15mg). So what I've been doing is just recon two at a time and when I filter it I put both into a new sterile vial. I suppose if you're not filtering it's extra work though. I'm only 3 months in and nowhere near the max dose though.
Does filtering help remove bacteria or is it mainly to filter out fillers/impurities?

I havent been doing this so far … you reckon I should start? Will I lose any peptides or decrease the strength if I filter?
 
Does filtering help remove bacteria or is it mainly to filter out fillers/impurities?

I havent been doing this so far … you reckon I should start? Will I lose any peptides or decrease the strength if I filter?
No you don't need to do this.
 
That seems crazy to use that much. I hope long term you will be ok. T definitely comes 60mg vials. In the long run though I think less contamination is key if you have to open more vials for often.
Not really man here in Australia we have 60mg pens of Mounjaro which administers 15mg doses.

So I believe the highest dose for tirz is 15mg.

7.5mg is only half of that …

Same we Wegovy (semaglutide)
Highest dose is 2.4mg per week. So I am still under.

For me the other problem is I am insulin resistant so lower doses doesnt work for me …

Im fighting my hardest battle to lower my insulin resistance.
 
I am not sure if you realise it or not but your vial sizes are too small.

Allow me to explain. I currently stack 3 peptides.

7.5mg tirz (once a week)
8mg reta (4mg twice a week)
2mg sema (1mg twice a week)

Now with the current size vials that most suppliers sell lets do the maths.

30mg vial tirz = i only get 4 doses from a vial
20mg vial reta = i only get 2.5 doses from a vial
10mg sema = i only get 5 doses

Why are you guys not increasing your vial sizes?

I think tirz should be a min 60mg vial
Reta should also be 60mg vial
Sema should be min 50mg vial

Let’s not mention cagri or motsc etc.

Sure the small vials like 10mg sizes are great as a sample but not for long term use.

This stack works for me the best. I have tried with different amounts and different split doses but this works the best for me.

Sema helps with food noise and appetite. Tirz keeps my glucose levels in check. Reta to bring down my weight.
I’m waiting for the /s please post the /s
 
Vial sizes are linked to 1. Consumer demand and 2. Pharma trials.

Reta goes up to 12. So 48 should be highest. I've seen 30s. Most stack it or use low doses.
Tirz goes up to 15. So 60. Already exists.
Sema goes to 2.4. Hell, I've seen 20, most have 10s.
Cagri goes to 4. Most have tens, but I seldom see anyone using cagri by its self and dosing over 2.

Based on demand, I could see reta getting a bigger size vial for sure.

If I get a good deal on smaller vials, I just filter two of them into 1 vial.
 
Reta goes up to 12. So 48 should be highest. I've seen 30s. Most stack it or use low doses.
Tirz goes up to 15. So 60. Already exists.
Sema goes to 2.4. Hell, I've seen 20s
Cagri goes to 4. Most have tens, but I seldom see anyone using cagri by its self and dosing over 2.

I think the vials are fine and linked to prescribed dosages. Based on demand, I could see reta getting a bigger size vial for sure.
honestly, since we're researching things here, Tirz is in clinical trials for 25mg weekly, so might as well have a 100mg option for researchers.
 
go big or go home. Amirite?!
Lol yeh and also usually we need a stockpile of something like once you start on these peptides and your body becomes more efficient in processing carbs and lowering glucose etc so I want to have a stable and long lasting supply without having to worry about off crap im down to my last vial so I have to start lowering my dose…
Also cost another issue man so the more you buy the better a price you will get as well. I wonder what it costs these vendors to actually make a vial of 60mg tirz? My guess maybe less than $10usd?
 
honestly, since we're researching things here, Tirz is in clinical trials for 25mg weekly, so might as well have a 100mg option for researchers.
What percentage of gray market consumers do you think are using over 15mg? Hitting moq will be tough for some of this.
 
honestly, since we're researching things here, Tirz is in clinical trials for 25mg weekly, so might as well have a 100mg option for researchers.
Can you post this research please. My understanding of tirz is max safe dose is 15mg a week. So we should not exceed this dose. Are you sure you saw 25mg trial?
 
Can you post this research please. My understanding of tirz is max safe dose is 15mg a week. So we should not exceed this dose. Are you sure you saw 25mg trial?

They don't specifically say it, but word on the street is that these "investigational tirzepatide doses" and "high dose 1" and "high dose 2" is 20mg and 25mg, respectively.
 
Vial sizes are linked to 1. Consumer demand and 2. Pharma trials.

Reta goes up to 12. So 48 should be highest. I've seen 30s. Most stack it or use low doses.
Tirz goes up to 15. So 60. Already exists.
Sema goes to 2.4. Hell, I've seen 20, most have 10s.
Cagri goes to 4. Most have tens, but I seldom see anyone using cagri by its self and dosing over 2.

Based on demand, I could see reta getting a bigger size vial for sure.

If I get a good deal on smaller vials, I just filter two of them into 1 vial.
What happens if someone decides to take 15mg reta a week? Is that a dangerous dose or due to side effects it was never tested but safe to do so if needed?
 
Not really man here in Australia we have 60mg pens of Mounjaro which administers 15mg doses.

So I believe the highest dose for tirz is 15mg.

7.5mg is only half of that …

Same we Wegovy (semaglutide)
Highest dose is 2.4mg per week. So I am still under.

For me the other problem is I am insulin resistant so lower doses doesnt work for me …

Im fighting my hardest battle to lower my insulin resistance.
You're comparing your dosage of single components of your stack vs. the trial amounts, none of which involved stacking these peptides. Cagrilintide and Semaglutide are the only ones we have research results on stacking. Most people deciding to be cowboys and stacking these unstudied combos tend to go for significantly smaller doses for at least some of the components in the stack, so you're an outlier among outliers. That's why people are showing surprise.

That isn't to say what you're doing is bad - but that's because none of us know. Maybe this is a great way to tackle the problem. Maybe there are interference effects. Maybe you're going to overwhelm your system and there will be major detrimental impact to you. People using retatrutide at all are a tiny fraction of the people on GLP-1s, people stacking multiple in general is also a tiny fraction, and there might only be a few dozen people in the world stacking reta/tirz/sema at the levels you are.
 
as a side question if I may, after you reconstitute a peptide like reta. What happens if you keep it in the fridge and use it over a 3 month period? Does it become weaker or something? Jan of this year I went on a long 3 month holiday and took a few boxes of ozempic with me and kept in the fridges and used my dose accordingly. I mean it didnt expire or anything so is this 3 weeks use by thing more like a myth?
Sorry guys Im new and have a lot of questions and am trying my best to learn as much as I can
 

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