Had started berberine a few years ago as there were claims that it improved insulin sensitivity. discovered however that it is contraindicated with many of the new blood thinners. also there was a new published article questioning its effect on fat storage.
Treatment with the supplement berberine failed to reduce visceral adipose tissue or liver fat in adults with obesity and metabolic dysfunction-associated steatotic liver disease (MASLD), a randomized trial found.
JAMA Network Open
Source Reference: Lei L, et al "Berberine and adiposity in diabetes-free individuals with obesity and MASLD: a randomized clinical trial" JAMA Netw Open 2026; DOI: 10.1001/jamanetworkopen.2025.54152.
Treatment with the supplement berberine failed to reduce visceral adipose tissue or liver fat in adults with obesity and metabolic dysfunction-associated steatotic liver disease (MASLD), a randomized trial found.
JAMA Network Open
Source Reference: Lei L, et al "Berberine and adiposity in diabetes-free individuals with obesity and MASLD: a randomized clinical trial" JAMA Netw Open 2026; DOI: 10.1001/jamanetworkopen.2025.54152.