Do GLP-1 Agonists Worsen Diabetic Retinopathy?

[ZippityDooDah]

Do GLP-1 Agonists Worsen Diabetic Retinopathy?

Patients taking glucagon-like peptide-1 agonists were more likely to progress from nonproliferative diabetic retinopathy to proliferative disease or diabetic macular edema than those who took sodium-glucose cotransporter-2 inhibitors.

www.medscape.com

 

[Tidalwave]

Yes, it’s a possibility. There have been some studies that suggest that GLP-1 agonists, like tirzepatide, may worsen diabetic retinopathy. Diabetic retinopathy is a complication of diabetes that can lead to vision loss.
The proposed mechanism is that GLP-1 agonists may increase the risk of diabetic retinopathy by causing a small increase in blood glucose levels. This increase in blood glucose may cause damage to the blood vessels in the retina. However, it’s important to note that the evidence is still inconclusive and more research is needed to determine the true risk.

 

[Tidalwave]

Do GLP-1 Agonists Worsen Diabetic Retinopathy?

Patients taking glucagon-like peptide-1 agonists were more likely to progress from nonproliferative diabetic retinopathy to proliferative disease or diabetic macular edema than those who took sodium-glucose cotransporter-2 inhibitors.

www.medscape.com

Another study, published in the CDC, found that a significant percentage of people with diabetes had diabetic retinopathy, and that a smaller percentage had vision-threatening retinopathy.