Reta users - anyone experience increase in appetite initially?

tendency

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Madison
So my wife started Reta a couple weeks ago at .5mg 2x/week. She's noticed a slight increase in her appetite at times along with some additional eating. Is this common for folks when they start off at a low initial dose?
 
I was on semaglutide for 3 months at 1 mg per week, but after my prescription coupon expired, I switched to Reta. My appetite came back after a week. I started at 1 mg once a week, then increased to twice a week. Each week, I raised both doses by 1 mg until I found that 3 mg twice a week provided similar appetite suppression. I’ve now settled at 4 mg on Mondays and 5 mg on Thursdays. I titrated pretty fast. I haven’t tried a 9 mg single dose yet. I’m pretty sure it would make me sick.

There’s a chart circulating that compares receptor activation strength among the big three, and Reta ranks as the weakest for GLP-1 activation, which explains what she’s experiencing. I’d suggest starting at 1 mg twice a week and adjusting from there.
 
I was on semaglutide for 3 months at 1 mg per week, but after my prescription coupon expired, I switched to Reta. My appetite came back after a week. I started at 1 mg once a week, then increased to twice a week. Each week, I raised both doses by 1 mg until I found that 3 mg twice a week provided similar appetite suppression. I’ve now settled at 4 mg on Mondays and 5 mg on Thursdays. I titrated pretty fast. I haven’t tried a 9 mg single dose yet. I’m pretty sure it would make me sick.

There’s a chart circulating that compares receptor activation strength among the big three, and Reta ranks as the weakest for GLP-1 activation, which explains what she’s experiencing. I’d suggest starting at 1 mg twice a week and adjusting from there.
Good stuff thanks for the info; I'll talk to the wife about raiding her dose.
 
So my wife started Reta a couple weeks ago at .5mg 2x/week. She's noticed a slight increase in her appetite at times along with some additional eating. Is this common for folks when they start off at a low initial dose?
Is she gaining weight? If not, it doesn't really matter if she has more appetite. Most people have more appetite on reta than other glps.


There’s a chart circulating that compares receptor activation strength among the big three, and Reta ranks as the weakest for GLP-1 activation, which explains what she’s experiencing.
That chart is completely irrelevant to real world effects. It doesn't explain anything because it doesn't apply to how the drug works in a real human body.
 

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