So my wife started Reta a couple weeks ago at .5mg 2x/week.  She's noticed a slight increase in her appetite at times along with some additional eating.  Is this common for folks when they start off at a low initial dose?
				
			Good stuff thanks for the info; I'll talk to the wife about raiding her dose.I was on semaglutide for 3 months at 1 mg per week, but after my prescription coupon expired, I switched to Reta. My appetite came back after a week. I started at 1 mg once a week, then increased to twice a week. Each week, I raised both doses by 1 mg until I found that 3 mg twice a week provided similar appetite suppression. I’ve now settled at 4 mg on Mondays and 5 mg on Thursdays. I titrated pretty fast. I haven’t tried a 9 mg single dose yet. I’m pretty sure it would make me sick.
There’s a chart circulating that compares receptor activation strength among the big three, and Reta ranks as the weakest for GLP-1 activation, which explains what she’s experiencing. I’d suggest starting at 1 mg twice a week and adjusting from there.
Is she gaining weight? If not, it doesn't really matter if she has more appetite. Most people have more appetite on reta than other glps.So my wife started Reta a couple weeks ago at .5mg 2x/week. She's noticed a slight increase in her appetite at times along with some additional eating. Is this common for folks when they start off at a low initial dose?
That chart is completely irrelevant to real world effects. It doesn't explain anything because it doesn't apply to how the drug works in a real human body.There’s a chart circulating that compares receptor activation strength among the big three, and Reta ranks as the weakest for GLP-1 activation, which explains what she’s experiencing.
