Semi to Lira to Tirz, so far

[LN777]

I was fortunate enough to have insurance pay for a metabolic clinic visit almost 2 years ago, where I was diagnosed as insulin resistant. Prescribed Semi and lost some weight but had brutal side effects. Based on the side effects, was moved (down) to Lira. Side effects went down, but so did the weight loss.

Lost my insurance - so explored my options and went to compounded Tirz (still working through my stockpile).

Started at 225 lbs (5 ft 9 male), down to 180. Need to start weight resistant training, but have been good about cardio. Figure I have about 10 lbs of fat left to lose, but have muscle to gain. Currently at 8 mg of Tirz every 4 days, which puts me at a peak just under 15 mg.

Diet is <mostly> good, high protein, low carbs, no junk food food or processed food. Only exception I'd say is alcohol - have a few glasses of wine each night, which I'm sure is what is keeping from my goal weight. I am sadly not one of the people where Tirz (or Lira or Semi) stopped the cravings for alcohol. Maybe Reta will - or just white knuckling it....

I have 6-8 months left of Tirz stockpile, and plan to go "gray" after that. Hoping to be on maintenance and then based on my research want to move to Reta (or a stacking combo).

Happy to have found this community - appreciate any advice.

 

[indolent]

Welcome! It sounds like you've done a lot of learning in advance (especially if you're doing split dosing with sense of the resultant load).

If you haven't already done so I suggest you spend your time, between now and when you select a gray vendor, learning all about reconstituting, the free online calculators which make it easier, and the specific supplies you'll have to buy separately.

 

[Calm Logic]

and the specific supplies you'll have to buy separately.

Since I believe in filtering, I found it easier to just buy a peptide recon kit. In any case, I like the peptide recon kits as a guide, like at Underground Supply or Peptide Test.

 

[Iamnew2this]

Welcome and good luck to you!

 

[StonePny]

I was fortunate enough to have insurance pay for a metabolic clinic visit almost 2 years ago, where I was diagnosed as insulin resistant. Prescribed Semi and lost some weight but had brutal side effects. Based on the side effects, was moved (down) to Lira. Side effects went down, but so did the weight loss.

Lost my insurance - so explored my options and went to compounded Tirz (still working through my stockpile).

Started at 225 lbs (5 ft 9 male), down to 180. Need to start weight resistant training, but have been good about cardio. Figure I have about 10 lbs of fat left to lose, but have muscle to gain. Currently at 8 mg of Tirz every 4 days, which puts me at a peak just under 15 mg.

Diet is <mostly> good, high protein, low carbs, no junk food food or processed food. Only exception I'd say is alcohol - have a few glasses of wine each night, which I'm sure is what is keeping from my goal weight. I am sadly not one of the people where Tirz (or Lira or Semi) stopped the cravings for alcohol. Maybe Reta will - or just white knuckling it....

I have 6-8 months left of Tirz stockpile, and plan to go "gray" after that. Hoping to be on maintenance and then based on my research want to move to Reta (or a stacking combo).

Happy to have found this community - appreciate any advice.

Hi, welcome!
In re: wine/craving, look into low dose naltrexone (LDN). Someone close to me is using it for this very thing very successfully. Low dose as in starting at around 1.5 or 3mg, landing at 4, daily (nightly). It has an added benefit of bolstering your tirzepatide and added appetite suppression.
If you're already working with a telehealth for compounding, you may be able to get it through them, doctor will also prescribe. Also available from India pharmacies.
Because regardless of what we've been told, wine is inflammatory.

 

[Calm Logic]

Oh wow, I'm going to add it to my list:

Low-Dose Naltrexone: A Future Gold Medalist?

American Family Physician Community Blog, Low-Dose Naltrexone: A Future Gold Medalist?, written by Lilian White, MD.

www.aafp.org

Low doses (e.g., 4.5 mg) of naltrexone are being studied for use in a wide variety of disorders...Many chronic conditions have immunomodulation and relief of neuroinflammation at the core of their pathophysiology, making low-dose naltrexone a medication with many potential applications. Currently, it has been studied for use in fibromyalgia, post-COVID syndrome, postural orthostatic tachycardia syndrome (POTS), Crohn’s disease, chronic pain, multiple sclerosis, inflammatory skin disorders, and others.

 

[StonePny]

Oh wow, I'm going to add it to my list:

Low-Dose Naltrexone: A Future Gold Medalist?

American Family Physician Community Blog, Low-Dose Naltrexone: A Future Gold Medalist?, written by Lilian White, MD.

www.aafp.org

I'll tell you, @Calm Logic, it needs talking about. My daughter's friend suffers from Crohn's (so bad, poor girlie) and I discovered LDN when reading up on treatments for that. It is showing great promise for Crohn's, IBS, other AI and gastro inflammatory situations.
I started with LSH for compounding and they offer it as "non-glp 1 weight loss" oral med option