Tesa+ipa premixed 10:5

[StingerBee]

Ok so I’ve done some reading and the dose for tesa during one trial in HIV patients was 2mg daily.
I have ordered a premix tesa+ipa in. 5:3mg ratio.
I am a female, no hiv. I train everyday and my diet is almost in check (thanks reta for helping here)
I have belly fat I would like to burn.
Would a split dose morning/night be more beneficial or one dose before bed 2 hours fasted?
I train in the mornings 4 days a week heavy weights, 1 day a week HIIT (always in the mornings, always fasted) this is why I ask about the benefit of a split dose.
Should I start at a full dose or see if halving it would bring the wanted effects?
I know there’s really only one way to find out (try for myself) but was wondering if any females out there had any experience with this combo.
Thank you

 

[sepehr]

I strongly doubt the premixed Tesa 10mg+Ipa 5mg are the effective dose for fat burn and muscle building.

Dr. William Seeds recommended protocol for men and women is:

At night before going to bed:
- 1mg Tesamorelin *(reconstituted as 1ml)*
- plus 100mcg Ipamorelin

First thing in the morning:
- 100mcg Ipamorelin

Notes:
- He suggests to take 1 or 2 day holiday every week (~5days a week).
- For older people, Seeds might choose 50mcg of IPA instead of 100mcg. Individual responses matter.

—

He explicitly mentions taking more than 100mcg of IPA is not effective and is a waste of money. When taken with Tesa, my understanding is that IPA plays a role to lift Somatostatin ratelimiting effect, and allow secretion of GH.

More acurate quote from his book "Peptide Protocols":

> "However, we need to keep in mind that using a GHRH by itself does not necessarily mean there will be an immediate endogenous growth hormone release. The machinery in the anterior pituitary secretagogue is set in motion to produce the pulse of growth hormone, but the hypothalamus still controls the release of GH, with somatostatin having a rate-limiting effect. In this way, though GH will eventually be released, it will not be until somatostatin inhibition is lifted. It’s for this reason that it’s important to consider using a GHRP in combination to ensure endogenous growth hormone release within a desired 20-minute window"

"It’s also important to understand how consumed nutritional substrates affect GHRH/GHRP peptides. Pure protein has no effect on endogenous release of GH; on the other hand, carbohydrate and fatty acid consumption can blunt the GH release. I recommend following the simple rule of no food for up to 30 minutes after GHRH/GHRP use and no food 1½ hours before use. These are the only peptides now known to be affected by nutrition. A general scheme of use could be utilizing them before bedtime to ensure stage 4 sleep improvement and first thing in the morning before eating breakfast."

—

If you can manage the interviewer attitude, here's a useful cut from Dr. Seeds on "Somatostatin Inhibition" and "Tesa+IPA protocol":

 

[StingerBee]

Wow thank you so the 10:5 ratio of premixed is alllll wrong
Grr. I have 10 vials coming.

Oh well I will end up using and doing a trial and error way and see how I go I guess….
Thanks for posting the interview I will watch it now

 

[touringsedan]

Wow thank you so the 10:5 ratio of premixed is alllll wrong
Grr. I have 10 vials coming.

Oh well I will end up using and doing a trial and error way and see how I go I guess….
Thanks for posting the interview I will watch it now

I have been having the same issue with buying the blends because of Dr. Seeds statements about 100mcg max per dose as that is all the receptors can handle and higher only increases the odds of an allergic response. Amazing how most are 10:5 and I have seen one that 1:1.
I just made my own blend to get around this and it worked well.

 

[skunknuts]

Just buy pure Tesa and mix in your vial

 

[StingerBee]

Too late I am awaiting 10;vials all paid for

 

[skunknuts]

Too late I am awaiting 10;vials all paid for

No, I mean buy a kit of Tesa and then mix with your prestacked vial to get the ratio you want. Maybe use 3 vials of Tesa and make it 35:3 in 3 ml BAC total, and then one 10 unit dose would be 100 mcg. IPA and 1.15 mg. Tesa, which seems a reasonable place to start with dosing...

 

[StingerBee]

No, I mean buy a kit of Tesa and then mix with your prestacked vial to get the ratio you want.

Ooooooh I get it!!! Use the premix for ipamorelin doses and use a separate tesa only for tesa doses…..cleverrrrr!!!!!!

 

[skunknuts]

Ooooooh I get it!!! Use the premix for ipamorelin doses and use a separate tesa only for tesa doses…..cleverrrrr!!!!!!

I added more to my reply to develop the thought and make it easiest in my mind.

 

[StingerBee]

I added more to my reply to develop the thought and make it easiest in my mind.

Super!!! Thank you