What peptides do you guys use for anxiety ? Pinealon?

[Jack Paulie]

Hi,
I'm currently using Selank for Anxiety treatment, but since I don't want to use it forever, I would like to switch up with another anxiety reducing peptide.
Anyone with good experience on this?

I've of course read about PE 22-28, P21, Semax but it looks like these are more for brain fog etc.

Pinealon I haven't tried yet, but it looks promissing on the stress aspect of anxiety..

 

[miameow]

Not a peptide, but I take propranolol and it really is effective in reducing the physical symptoms of anxiety. You don't need to be on it forever, you just pop a pill when you feel anxious. I have selank on the way so it would be interesting to test as well.

 

[Jack Paulie]

Not a peptide, but I take propranolol and it really is effective in reducing the physical symptoms of anxiety. You don't need to be on it forever, you just pop a pill when you feel anxious. I have selank on the way so it would be interesting to test as well.

Thanks for the tip, but beta blockers isn’t a preferred solution for me😛

 

[sixgallery]

Not a peptide, but I take propranolol and it really is effective in reducing the physical symptoms of anxiety. You don't need to be on it forever, you just pop a pill when you feel anxious. I have selank on the way so it would be interesting to test as well.

I am being super targeted by places offering this in gummy form on FB. I'm still in source discussion prison but can I ask if you're using a local doc, TH or other type of provider?

 

[miameow]

I am being super targeted by places offering this in gummy form on FB. I'm still in source discussion prison but can I ask if you're using a local doc, TH or other type of provider?

They really make gummies out of everything these days!

India, is my source.

 

[Gt3294a]

Hi,
I'm currently using Selank for Anxiety treatment, but since I don't want to use it forever, I would like to switch up with another anxiety reducing peptide.
Anyone with good experience on this?

I've of course read about PE 22-28, P21, Semax but it looks like these are more for brain fog etc.

Pinealon I haven't tried yet, but it looks promissing on the stress aspect of anxiety..

Personally, I don’t think any peptide sufficiently acts on the CDN to have major anxiety reducing effects. But for that reason, the best anxiety medicines and research compounds are always playing with the devil, eg, Phenibut, and often the devil bites you in the ass.

 

[paisleyfan]

is there a reason you're wanting a peptide for anxiety, rather than pursuing a clinical anxiety treatment, like SSRI's?

 

[TazaTaza]

PE 22 28 worked wonders for me. I originally picked it up for its alleged mechanism to relieve depression.

I've been taking it for about 6 weeks and feel instant mental relief. I no longer have a pit in my stomach over things worrying, no more racing thoughts overthinking every little thing, overanalyzing, having choice paralysis etc.

To me for pe2228 it's doing everything Adamax/Semax was supposed to do, so take my advice w/grain of salt. It helped tremendously w/task initiation for me and quieting down my thoughts.

 

[rkbleddyn]

So far, for me, the best thing is Semax. Selank has very little effect on me. All of us are different, so you never really know unless you try. Experimenting with Oxytocin now. I don't really have anxiety, but I am under a lot of stress because of my job and Semax helps a lot with this.

Also, If you are on a GLP1 (I'm on Tirzepatide), you also may notice that it sort of dampens down your enthusiasm for other stuff besides food, like, well... everything? So the Semax comes in there too because it can increase dopamine, same reason I am experimenting with Oxytocin in the afternoons and it can also get you into that afternoon chill mode. Only 2 days, so cannot really comment on the efficacy of that one. It does give you a sort of 'nice' feeling, for lack of better words.

 

[lastresort]

I use this thing called "meat," which is protein.

 

[Jack Paulie]

is there a reason you're wanting a peptide for anxiety, rather than pursuing a clinical anxiety treatment, like SSRI's?

I just want to use something that doesn’t have to many adverse effects. My anxiety is not extreme, it just comes and goes and hits a bit harder than for the normal NPCs out here😛
And given my enthusiasm for these peptides I thought why not try them out 🙂

 

[rkbleddyn]

I just want to use something that doesn’t have to many adverse effects. My anxiety is not extreme, it just comes and goes and hits a bit harder than for the normal NPCs out here😛
And given my enthusiasm for these peptides I thought why not try them out 🙂

I suffered from anxiety quite a bit at one point in my life and nothing worked that doctors provided. In fact, I hated all of it, it made the anxiety worse. Besides benzos, that worked but it needs to be a short term solution because of the negative sides, including being addictive. Not sure what is available in Norway, but the Semax for me works well and you can also get a nasal spray form which seems to be very popular.

 

[paisleyfan]

I just want to use something that doesn’t have to many adverse effects. My anxiety is not extreme, it just comes and goes and hits a bit harder than for the normal NPCs out here😛
And given my enthusiasm for these peptides I thought why not try them out 🙂

got it! I'm a former pharmacy tech, so I know quite a bit about medication. it's not a peptide, but some doctors prescribe antihistamines (allergy meds like benadryl) for anxiety. some people say that if you're asleep, you're not anxious! 😆

 

[rkbleddyn]

got it! I'm a former pharmacy tech, so I know quite a bit about medication. it's not a peptide, but some doctors prescribe antihistamines (allergy meds like benadryl) for anxiety. some people say that if you're asleep, you're not anxious! 😆

Hydroxyzine. Works well for allergies, not too well for anxiety, my personal experience. Will also put you to sleep very quickly.

 

[Flash-BCR]

Thanks for the tip, but beta blockers isn’t a preferred solution for me😛

I have beta blockers that I use occasionally if I have to do a major presentation...but I recently made up a selank nasal spray and 'for me', it gives me very similar effect as the BBs. It was completely unexpected, so its not a placebo effect. At work, I do one spray in the morning and afternoon....GL

 

[ultima thule]

I'm on Semax since Monday, so only 3 shots of .5mg so far. Can't say I'm more focused or something like that, but feel more unwind and relaxed like. It's only 3 shots, so it might be placebo, or just coincidence. Especially for the last few days we have a real summer in Ireland, which is unreal, so that might be another reason of my good mood...will see how it goes in the next few days and will update the insight on Semax...

 

[rkbleddyn]

I'm on Semax since Monday, so only 3 shots of .5mg so far. Can't say I'm more focused or something like that, but feel more unwind and relaxed like. It's only 3 shots, so it might be placebo, or just coincidence. Especially for the last few days we have a real summer in Ireland, which is unreal, so that might be another reason of my good mood...will see how it goes in the next few days and will update the insight on Semax...

They've been using it in Russia for 20 years and OTC for 7 years, so there's plenty of anecdotal evidence of it's efficacy. Good luck, everyone reacts differently.

 

[ultima thule]

They've been using it in Russia for 20 years and OTC for 7 years, so there's plenty of anecdotal evidence of it's efficacy. Good luck, everyone reacts differently.

Yeah I know the story behind Semax, and that's why I wanted to give it a try. Hope it makes me a bit smarter tho 😆

 

[rkbleddyn]

Yeah I know the story behind Semax, and that's why I wanted to give it a try. Hope it makes me a bit smarter tho 😆

Lol, I'd like that too. Right now I'm very happy with it because it makes me a lot calmer under stress.

 

[ultima thule]

Lol, I'd like that too. Right now I'm very happy with it because it makes me a lot calmer under stress.

Yeah, as I said above I got very same feeling. But again it doesn't have to be Semax straightforward, due to the current circumstances...think will know more after at least 2 weeks of the cycle...

 

[wildweasel]

Not a peptide, but I take propranolol and it really is effective in reducing the physical symptoms of anxiety. You don't need to be on it forever, you just pop a pill when you feel anxious. I have selank on the way so it would be interesting to test as well.

It works well

 

[Jfrick11]

Hi,
I'm currently using Selank for Anxiety treatment, but since I don't want to use it forever, I would like to switch up with another anxiety reducing peptide.
Anyone with good experience on this?

I've of course read about PE 22-28, P21, Semax but it looks like these are more for brain fog etc.

Pinealon I haven't tried yet, but it looks promissing on the stress aspect of anxiety..

I kind of think it depends on the level and type of anxiety you have. For me, I do use peptides, but without a small dose of Sertraline, I’m just not myself. I’m a better human on it and it takes the edge off my busy brain. My anxiety is like having a ticker tape running in the background 24/7..... thoughts, lists, worries, conversations, plans, all moving at once.

A lot of these compounds seem to help certain pieces of the puzzle (sleep, stress, focus...) , but not always the core issue and they’ve never fully replaced what the sertraline does for my nervous system regulation.

For me personally, the best has been combining tools instead of expecting one thing to magically fiix me. Better sleep, less alcohol, exercise, nervous system regulation, peptides, and a low-dose SSRI together work way better for me together.

 

[Pocket]

got it! I'm a former pharmacy tech, so I know quite a bit about medication. it's not a peptide, but some doctors prescribe antihistamines (allergy meds like benadryl) for anxiety. some people say that if you're asleep, you're not anxious! 😆

Can confirm. Half of a benedryl slows me down enough to take the edge off of an anxiety spike but keeps me together enough to still function normally. My doctor told me to try it because I was wary about getting prescribed benzos.

 

[Romulusguy]

I'm on Semax since Monday, so only 3 shots of .5mg so far. Can't say I'm more focused or something like that, but feel more unwind and relaxed like. It's only 3 shots, so it might be placebo, or just coincidence. Especially for the last few days we have a real summer in Ireland, which is unreal, so that might be another reason of my good mood...will see how it goes in the next few days and will update the insight on Semax...

Have you tried making a nasal spray out of the Semax? I remember reading it is more effective that way and I can testify to the effectiveness of the nasal spray myself 🙂

 

[ultima thule]

Have you tried making a nasal spray out of the Semax? I remember reading it is more effective that way and I can testify to the effectiveness of the nasal spray myself 🙂

I haven't actually. And you right, that there's many opinions about superiority nasal sprays over injections, but some users find it on the contrary. Think it's an individual matter eventually. One factor is certain that ns works immediately, but shorter...it looks similar for me to the traditional charlie vs crack debate 😆

 

[Jack Paulie]

PE 22 28 worked wonders for me. I originally picked it up for its alleged mechanism to relieve depression.

I've been taking it for about 6 weeks and feel instant mental relief. I no longer have a pit in my stomach over things worrying, no more racing thoughts overthinking every little thing, overanalyzing, having choice paralysis etc.

To me for pe2228 it's doing everything Adamax/Semax was supposed to do, so take my advice w/grain of salt. It helped tremendously w/task initiation for me and quieting down my thoughts.

Thanks for the feedback, will have to add PE2228 to my next purchase then 🙂

 

[ussop]

PE 22 28 worked wonders for me. I originally picked it up for its alleged mechanism to relieve depression.

I've been taking it for about 6 weeks and feel instant mental relief. I no longer have a pit in my stomach over things worrying, no more racing thoughts overthinking every little thing, overanalyzing, having choice paralysis etc.

To me for pe2228 it's doing everything Adamax/Semax was supposed to do, so take my advice w/grain of salt. It helped tremendously w/task initiation for me and quieting down my thoughts.

Good for seizures also?