I accidentally froze a few bottles of Hospira a while back. After checking AI and a few folks here weighing in, I decided to chuck em...From gemini but you should verify with other sources too:
Yes. Freezing precipitates the benzyl alcohol preservative, which reduces its antimicrobial effectiveness and can lead to bacterial growth upon thawing. Additionally, ice expansion often creates microscopic cracks in the glass vial or dislodges the rubber stopper, compromising the sterile seal. Discard the vial.
@byefatlicia maybe you can give some input here?