What peptide didn't work for you?

Sema did nothing for me. I had some mild appetite suppression and that was it. I was about to get some Tirz from a compounder and a friend of mine asked if I had heard of Reta. The rest is history. Just hit the 50 lb mark this morning.

Every other peptide I've tried has done something where I can feel at least some effect. I don't really count SS-31 because the effects are so subtle, and at the organelle level, but others feel a clean energy. Mots-C is next in a few weeks.
 
Chili777 said:
Sema did nothing for me. I had some mild appetite suppression and that was it. I was about to get some Tirz from a compounder and a friend of mine asked if I had heard of Reta. The rest is history. Just hit the 50 lb mark this morning.

Every other peptide I've tried has done something where I can feel at least some effect. I don't really count SS-31 because the effects are so subtle, and at the organelle level, but others feel a clean energy. Mots-C is next in a few weeks.
Click to expand...
Sema also did nothing for me, I went to max dose too for several months. The only thing that went down was my bank balance
 
I think I’ve decided to ditch the 5 amino, which isn’t surprising, lots of folks have said they didn’t notice a difference. I’ll keep the NAD since it does seem to give me energy, even before I was doing it alongside 5 amino. That one was noticeable, 5 amino not so much. And I’m tired of daily pins! I think every other day is all I can manage.
 
Selank just made me tired and gave me a headache.

Tried it first thing in the morning. Quickly grew very tired and after a few hours got a headache. Switched to evenings. Same issue, only now I woke up in the middle of the night with the headache.

Guess that one just isn't for me. Semax, on the other hand, works great.
 
Mr.Tired said:
Selank just made me tired and gave me a headache.

Tried it first thing in the morning. Quickly grew very tired and after a few hours got a headache. Switched to evenings. Same issue, only now I woke up in the middle of the night with the headache.

Guess that one just isn't for me. Semax, on the other hand, works great.
Click to expand...
did you inject it or did you have it via a nasal spray?
 
CMA Pooky said:
I didn't feel any effects from Epitalon, but it is possible that it works behind the scenes for anti-aging. I'll continue to take it since I have a whole kit and the price for it is reasonable.
Click to expand...
Are you taking it SubQ or IN?
 
Epitalon did nothing as far as I can tell. I was doing the Anela protocol at 500mcg for 10 on 20 off. Did 3 cycles and nothing. I think I might try the old protocol of 5-10mg for 20 days and see if that does anything.

Also SLU-PP-332 and 5-amino-1mq hasn't done anything noticeable so far. I take 2-3mg of oral slu and 3mg of subq 5amino. I heard great things about mega-dosing SLU but that seems insanely expensive. I might go up to 5mg of 5amino and if I still don't feel anything, I'm going to throw in the towel on them both.
 
I do not see KLOW on this list, which makes me laugh because as I've said, so many people are using KLOW to prevent loose skin. We don't actually know if it IS preventing loose skin in any way, because if we don't have loose skin, we don't know if we WOULD have had it if we hadn't used the KLOW. And if we do have some, we don't know if it would have been WORSE without it. And so none of us on it dare stop.
 
MOTS-C, but maybe I didn't try it long enough.
Epitalon made me feel extremely fatigued and groggy. It made my SO's chronic pain much worse and felt way sicker.
 
MOTS-C as well and Nad+(not exactly a peptide but still). More than half way through. Guess ill keep trying
 
rhood said:
MOTS-C as well and Nad+(not exactly a peptide but still). More than half way through. Guess ill keep trying
Click to expand...
I found the NAD efficacy changed depending on the source. Some I felt nothing, others had a more sustained effect of energy.
 
CMA Pooky said:
I didn't feel any effects from Epitalon, but it is possible that it works behind the scenes for anti-aging. I'll continue to take it since I have a whole kit and the price for it is reasonable.
Click to expand...
You will not feel some peptides as they work behind the scene to improve cellular health and overall health. SS-31 is a prime example of this as well as FOX-040.
 
Crumplestiltskin said:
300 mcg, if I'm calculating right? On a 50 unit syringe, I pulled 3 units.
Click to expand...
I used 1mg via IN. If you're older and have brain fog or other issues, a higher dosage is ok. If you're younger and have normal brain function, you may never feel it, but do what you're comfortable with. It still is probably working and it took me a few days to really feel it.
 
True story. I’ve seen people quit something after 2 months , then retry it later with better structure or source or whatever and suddenly it works.
 
390120 said:
After starting grey market GLP-1s I got curious about other peptides.

What didn't work for you?

There are so much hype around different compounds and a lot of success stories but it would be interesting to hear about what others have tried and did not work.
Click to expand...
Retatrutide did nothing for me! After loosing 25 kilogram on Mounjaro, I switched to Retatrutide, but the foodnoise and appetite came back, and I started to gain weight again!
Then I got grey Tirzepatide because of the price of MJ, and loose another 12 kilogram! From 88 kilogram in may 2025, down to 53 kilogram since december 2025, and keeping my weight with 5mg Tirzepatide and 0,5mg Cagrilintide weekly!
 
You must log in or register to reply here.

Trending Topics

Latest Posts

Forum Statistics

Threads
18,325
Posts
191,322
Members
61,353
Newest
GLPGIRLY
Back
Top Bottom