Just checking I got this right?

[techiemichael]

So just confirming I have this correct because I am S**t scared in getting this wrong.

If I buy a vial of 5MG Vial of Reta, I need to reconstitute it with 2ML of Bac water.
I do this by drawing the water from the BC vial and transfer it into the Reta vial by squirting the water at the sides of the vial and giving it a swirl till it’s full dissolved.

Then to administer it every 0.1ml is worth 10
Units. So if I wanted 1mg I would take 40
Units, which is what I want my starting dose to be?

Thanks for any advice in advance.

 

[Diytrader]

So just confirming I have this correct because I am S**t scared in getting this wrong.

If I buy a vial of 5MG Vial of Reta, I need to reconstitute it with 2ML of Bac water.
I do this by drawing the water from the BC vial and transfer it into the Reta vial by squirting the water at the sides of the vial and giving it a swirl till it’s full dissolved.

Then to administer it every 0.1ml is worth 10
Units. So if I wanted 1mg I would take 40
Units, which is what I want my starting dose to be?

Thanks for any advice in advance.

That math maths for me.

 

[Chili777]

For a 5mg vial, I'd use 1 ml BAC at most. Use a calculator like this one: https://peptidescalculator.com/

 

[woundcarping]

To take 1mg from a 5mg bottle, you’ll take 1/5th of the volume you reconstituted with.

100 units = 1mL

40 units or .4mL is 1/5 of 2mL.

 

[indolent]

Reverse calculator is your friend (link in signature), using a numbered stop on your syringe ... and be sure you know the tested mass of your vial, not just the nominal 5mg.

Avoid math ... it's nobody's friend.

 

[JuneBug1956]

5 mg vial has 5 -1 mg doses in it. I would put 50 units of BAC in it. 10 units is 1 mg dose. Or 100 units of BAC and each dose is 20 units for 1 mg. I like small volumes and less math. But you were correct. Calculators can be useful also.

 

[skeptick]

So just confirming I have this correct because I am S**t scared in getting this wrong.

If I buy a vial of 5MG Vial of Reta, I need to reconstitute it with 2ML of Bac water.
I do this by drawing the water from the BC vial and transfer it into the Reta vial by squirting the water at the sides of the vial and giving it a swirl till it’s full dissolved.

Then to administer it every 0.1ml is worth 10
Units. So if I wanted 1mg I would take 40
Units, which is what I want my starting dose to be?

Thanks for any advice in advance.

Good on you for asking. Best to be sure. Your math is correct if your vial is really 5mg. Not at all unusual for true contents to be +5% , which in this case is a 10% boost. Good for the wallet, maybe not so good other wise. Best to check your C.O.A. of the batch you received from your vendor. Reconstitution and dosage calculators are your friends....Me, personally, I'd use 1ml BAC and dose 20units, but that's just me...You do you.

 

[Chili777]

Good on you for asking. Best to be sure. Your math is correct if your vial is really 5mg. Not at all unusual for true contents to be +5% , which in this case is a 10% boost. Good for the wallet, maybe not so good other wise. Best to check your C.O.A. of the batch you received from your vendor. Reconstitution and dosage calculators are your friends....Me, personally, I'd use 1ml BAC and dose 20units, but that's just me...You do you.

Excellent point. An overfill is only a bonus if you know it's a bonus. Especially during your first few pins.

 

[techiemichael]

For a 5mg vial, I'd use 1 ml BAC at most. Use a calculator like this one: https://peptidescalculator.com/

Can I ask why 1ml of BAC?

 

[latviantower]

Can I ask why 1ml of BAC?

Smaller volume to pin.

I prefer larger volumes for two reasons.

1. More diluted solution is less likely to cause an injection site reaction (ISR). This is usually not an issue with GLP’s but can be common with “spicy” peps like GHK-Cu, NAD+, MOTS-C, glutathione, etc.

2. A larger volume is easier to measure and is more forgiving in terms of +/-% of accuracy. I’ve seen recon and dosing recommendations that end up requiring single digit units. Good luck drawing up exactly 8 units in a 1 ml insulin syringe! Any volume less than 30 units , I definitely prefer a 0.5 ml syringe.

 

[Chili777]

Can I ask why 1ml of BAC?

Yes, smaller volume. I like to keep my injections to 25 IU or less and will usually reconstitute the peptide to that amount or less, but that's me. With a GLP, there is no real benefit from a larger shot. I have a 50 mg vial and dose 10 mg, so I use 1 ml BAC for a 20 iU pin.

 

[V6R3W]

Not at all unusual for true contents to be +5% , which in this case is a 10% boost.

Huh? How does 5% = 10%?

What am I missing?

 

[80s.diver]

Smaller volume to pin.

I prefer larger volumes for two reasons.

1. More diluted solution is less likely to cause an injection site reaction (ISR). This is usually not an issue with GLP’s but can be common with “spicy” peps like GHK-Cu, NAD+, MOTS-C, glutathione, etc.

2. A larger volume is easier to measure and is more forgiving in terms of +/-% of accuracy. I’ve seen recon and dosing recommendations that end up requiring single digit units. Good luck drawing up exactly 8 units in a 1 ml insulin syringe! Any volume less than 30 units , I definitely prefer a 0.5 ml syringe.

Nice explanation. I was always going for the, less is more, but in this case more is more. Thanks.

 

[skeptick]

Smaller volume to pin.

I prefer larger volumes for two reasons.

1. More diluted solution is less likely to cause an injection site reaction (ISR). This is usually not an issue with GLP’s but can be common with “spicy” peps like GHK-Cu, NAD+, MOTS-C, glutathione, etc.

2. A larger volume is easier to measure and is more forgiving in terms of +/-% of accuracy. I’ve seen recon and dosing recommendations that end up requiring single digit units. Good luck drawing up exactly 8 units in a 1 ml insulin syringe! Any volume less than 30 units , I definitely prefer a 0.5 ml syringe.

Both excellent points. ThanX

 

[skeptick]

Can I ask why 1ml of BAC?

For me, 1cc/1ml/100units is much easier math and my personal preference is toward smaller injection amounts, all due to my minimal lack of experience.

 

[skeptick]

Huh? How does 5% = 10%?

What am I missing?

5ml vial may really contain 5.5mg(thought to contain 5mg)5.5 is greater than 5 by 10% which potentially could be A LOT. Everyone should always double check my math and spank on me if I gotit wrong please

 

[woundcarping]

5ml vial may really contain 5.5mg(thought to contain 5mg)5.5 is greater than 5 by 10% which potentially could be A LOT. Everyone should always double check my math and spank on me if I gotit wrong please

In your first post you said 5% isn’t unusual which in this case would be 10%.

Percents are percents. Maybe you meant .5mg overfill which would be 10% in this case?

I don’t get hung up on overfills, nor starting at 40% of the trialed and common dosing schedules.

 

[techiemichael]

but say I start small by using 1mg a week does it matter to much that there might be a slight over fill, when most people start on Reta at 2.5mg?

 

[Chili777]

but say I start small by using 1mg a week does it matter to much that there might be a slight over fill, when most people start on Reta at 2.5mg?

It depends on your response and it varies. The trials started at 2mg. I started with 1 mg twice a week before going to 2mg, once a week, and then moving to 4 mg, 6 mg, 8 mg and now 10 mg, each for 4 weeks. Some people stay at 2 mg or even 1 mg, because they can't handle the sides. If you're a good responder, it should be no problem.

 

[techiemichael]

Great. Thanks for all your help. That has given me some reassurance.

 

[HidingInPlainView]

but say I start small by using 1mg a week does it matter to much that there might be a slight over fill, when most people start on Reta at 2.5mg?

My wife and I both started at 2.5mg with no side effects.

 

[kill_bill]

Really helpful post for a noob like me, thank you!

I’m here reading as much as I can and was hoping that I’ve understood the basics so far!