dont_wanna_be_fat
GLP-1 Apprentice
Has anyone researched a Reta + Teso stack? If so, canyou share your experiences?
TIA
TIA
Teso and Reta
- Thread starter dont_wanna_be_fat
- Start date
GimmeABreak
Rabbit-hole Explorer
Why? Reta is a very power med all on its own. Teso is dangerous due to the 9 day half-life, I have also never heard of anyone that was on it longer than a couple of months, It's great the first few weeks but that half-life catches up with you.
Both meds are also known to increase your heart rate so you should consider that before researching. There is even a thread on this site from @peptideusername with a subject of Teso is awesome. Even he found that after a couple months, not so awesome.
https://glp1forum.com/threads/teso-is-awesome.1035/
This is a good description. It felt great for me at first, but then started to realize it was making me edgy and was affecting my sleep.
Nachosupremeo
GLP-1 Novice
🚫No Source Discussion🚫
Teso is great at the start, but like others have said it catches up to you. I started out at 250mg every day because that was the dose associated with less side effects from the study I read. Two weeks later I split that dose in half to 125mg every day, two weeks after that I went to 125 EOD. I’ve been doing the 125 EOD for about a week now, so far it’s been ok. Plenty of get up and go, less edgy/anxious feeling. When I took a break from it, it took about 2 days to get back to a base line feeling, but it’s not completely out of your system for 45 days. Side effects I noticed at the 250 dose were high anxiety, difficulty sleeping and constipation. At the smaller, less frequent dose I don’t have those.
Medex
GLP-1 Novice
🚫No Source Discussion🚫
I first thought this thread was about tesA. I don't know about teso, but 1mg 5 on 2 off of tesa I think is working for me. My scale says my visceral is down 3 points from 5 weeks ago. How my scale knows this is a mystery in itself, but I'm taking it as good news anyway
lessthanhalf
GLP-1 Specialist
Tesofensine is an effective drug in causing weight loss up to 9%, and has been studied in humans. It is also a reuptake blocker of serotonin, noradrenaline and dopamine, so basically a super antidepressant that has never been studied for depression. All the recent research is it combined with a beta blocker metoprolol to reduce the effects on increased heart rate and possibly other somatic symptoms that are similar to anxiety and can therefore cause increased anxiety. Which is pretty consistent with internet reports of that being a problem, and the long half life is not ideal either. Taking it with any psych medications could be a bad idea, and would need very careful study to avoid interactions that could be serious.
I thought about it quite seriously , to try to help maintain massive weight loss, but would have to stop other antidepressants I know work to take something that has never even been tested.
I thought about it quite seriously , to try to help maintain massive weight loss, but would have to stop other antidepressants I know work to take something that has never even been tested.
DFW007
GLP-1 Novice
🚫No Source Discussion🚫
Luckily I ve never taken any meds for anythig. Regrading anxiety etc, I think cbd is a great option. I once took it after massive anxiety when I had covid,Not sure what caused it.....covid or steroids but it was bad. I then took Yips 250mg cbd caps and I was literally fine. I would never ever take prescription drugs.I ve seen too many sucessful ppl having suicidal thoughts and a host of side effects.
For anxiety etc by itslef, folks should take 5htp. Inexpensive and you sleep well.
Precautions for 5htp:
Consult a healthcare provider before starting, especially if you are on antidepressants, SSRIs, SNRIs, or other serotonin‑affecting medications, as 5‑HTP can increase serotonin levels and raise the risk of serotonin syndrome. Not recommended for people with certain medical conditions or those taking high‑dose supplements without supervision.
