Separate stack or GLOW?

[amosmylove]

I'm sure this has been discussed but searching for it didn't get me anywhere.

Asking specifically about stacking BPC157, TB500 and GHKCU individually. Aka the GLOW stack.
I've done a full cycle of them all seperately.
500mcg Bpc and 2.5 mg ghkcu daily, then 250 mcg tb500 every 3rd day.
I know there is slight degradation of the GLOW after reconstitution at like 3-5% after 1 month or something close to that. Not concerned there.
My question is:
Everything I've read says tb500 daily is overkill/not ideal. So is GLOW then unideal? Should I keep ordering seperate peptide vials or cave and just get GLOW?

What happens when you take tb500 daily versus 2-3x/week?
Female here if that matters. Long history of aggessive athlete related injuries and my first cycle of this stack was pretty encouraging for how improved I felt. I also have hEDS and it definitely improved the constant aches and pains.

Also! How long of a break do I need to take? I did 6 weeks on. Currently about 1 week off and I've already had the stiffness/ carpal tunnel symptoms return so I'm itching to start another cycle.

 

[MFGamesta]

I take separate. It has allowed me to dial in my bpc and TB doses leaving ghk alone as I think 2mg is the max ghk I want to take.I do draw it all in the same needle though

 

[Researcher6076]

I started with the blend when I didn't know any better. Now I'm doing seperate, but in the same syringe. Ghk-cu, kpv every day. BPC-157 on resistance trading days. Tb-500 only added in if I have an acute injury. Plus I can vary my doses seperately, which I do from time to time.

 

[amosmylove]

I take separate. It has allowed me to dial in my bpc and TB doses leaving ghk alone as I think 2mg is the max ghk I want to take.I do draw it all in the same needle though

I am just tempted to go with glow because a kit is much cheaper than the 3 seperately.

 

[amosmylove]

I started with the blend when I didn't know any better. Now I'm doing seperate, but in the same syringe. Ghk-cu, kpv every day. BPC-157 on resistance trading days. Tb-500 only added in if I have an acute injury. Plus I can vary my doses seperately, which I do from time to time.

Do you think tb500 is completely overkill to do daily? I need to try to find more concrete evidence for/against it before I go with glow for simplicitys sake. It seems it might be worth it to stay seperate though.

 

[Researcher6076]

Do you think tb500 is completely overkill to do daily? I need to try to find more concrete evidence for/against it before I go with glow for simplicitys sake. It seems it might be worth it to stay seperate though.

Ghk-cu daily, continuously for sure. And there are good arguments for BPC-157 daily, continuously too, but not as compelling as those for ghk-cu. But the biology of tb-500 suggests only during acute recovery, maybe only at the beginning of acute recovery, and never continuously. The cancer acceleration risk alone is enough of a reason to just pull out tb-500 when you need it. They don't talk.much about the cancer accelerator aspect when they push glow, do they?

 

[amosmylove]

But the biology of tb-500 suggests only during acute recovery, maybe only at the beginning of acute recovery, and never continuously. The cancer acceleration risk alone is enough of a reason to just pull out tb-500 when you need it. They don't talk.much about the cancer accelerator aspect when they push glow, do they?

What about thymosin beta 4 instead of tb500? The non synthetic, full 43 amino chain more bioavailable OG of tb500? Does that have the same cancer acceleration concerns?

What I've read regarding tb500 and my own health history, it seems I should be doing 4mg 2x a week. Until injuries are healed up and then 1x a week as maintenance. But I was doing 250mcg every 3 days. So totally not what was suggested based on pep-pedia site.

 

[Beardboost]

For the price in can become insanely cheaper to do as KLOW stack, price for TB500 alone is not always great, makes you just want to reap the benefits from all rather than maybe the ''wolverine stack'' or buying certain peptides separate

 

[Kirbyzx6]

Yes KLOW has been the most cost effective process for me as well providing the maximum amount of benefits. My only recommendation is adding extra bac water which will throw off your 1:1 ratio but lessens the sting.

 

[MFGamesta]

I am just tempted to go with glow because a kit is much cheaper than the 3 seperately.

Then I would take the dose that maximizes the copper too ~2mg. I may do that when I run out. It took a lot of Wolverine to make a difference.

 

[PEP-Guardyola]

Oi pessoal.

Sou novo por aqui e estou pesquisando sobre GHK-Cu. Estou considerando usar 2mg diariamente por um período prolongado.

Notei que algumas pessoas recomendam suplementar com zinco juntamente com GHK-Cu para otimizar os resultados devido ao teor de cobre. Qual a dosagem que você está usando? Se é que está usando.

 

[Researcher6076]

What about thymosin beta 4 instead of tb500? The non synthetic, full 43 amino chain more bioavailable OG of tb500? Does that have the same cancer acceleration concerns?

What I've read regarding tb500 and my own health history, it seems I should be doing 4mg 2x a week. Until injuries are healed up and then 1x a week as maintenance. But I was doing 250mcg every 3 days. So totally not what was suggested based on pep-pedia site.

Correct dose for musculoskeletal injury Loading: 2.5 mg 2×/wk × 4–6 wk, then maintenance: 2–2.5 mg 1×/wk during continued recovery. With the caveat that we don't have evidence-based human dosing information. So we extrapolate from some very good equine data where TB-500 is used a lot, and from biological mechanistic understanding. 4 mg x 2/week is TOO HIGH. That even exceeds the dose used under physician supervision for cardiac intensive care.

TB-500 is much, much smaller than thymosin beta 4 improving its ability to be distributed to the injured tissue.

 

[amosmylove]

Correct dose for musculoskeletal injury Loading: 2.5 mg 2×/wk × 4–6 wk, then maintenance: 2–2.5 mg 1×/wk during continued recovery. With the caveat that we don't have evidence-based human dosing information. So we extrapolate from some very good equine data where TB-500 is used a lot, and from biological mechanistic understanding. 4 mg x 2/week is TOO HIGH. That even exceeds the dose used under physician supervision for cardiac intensive care.

TB-500 is much, much smaller than thymosin beta 4 improving its ability to be distributed to the injured tissue.

Thanks for this info. I wonder why peppedia was listing 3-5mg depending on root need.

 

[Researcher6076]

Thanks for this info. I wonder why peppedia was listing 3-5mg depending on root need.

Sadly, because a lot of those seemingly authoritative websites are just making stuff up.

 

[amosmylove]

Sadly, because a lot of those seemingly authoritative websites are just making stuff up.

Do you know anything about actual dosing of SS-31? Most protocols for the nad/ss31/motsc say 4mg/day of ss31. I looked into it and the only info I found was very inconsistent. I wonder if I could get away with like 2mg/day or if that would be a pointless waste of peptide.

 

[CNCCurrency]

Do you know anything about actual dosing of SS-31? Most protocols for the nad/ss31/motsc say 4mg/day of ss31. I looked into it and the only info I found was very inconsistent. I wonder if I could get away with like 2mg/day or if that would be a pointless waste of peptide.

 

[Researcher6076]

Do you know anything about actual dosing of SS-31? Most protocols for the nad/ss31/motsc say 4mg/day of ss31. I looked into it and the only info I found was very inconsistent. I wonder if I could get away with like 2mg/day or if that would be a pointless waste of peptide.

40 mg/day SC is the most commonly studied clinical regimen and has produced mixed functional outcomes across trials. Lower doses (0.5–10 mg/day) have produced biochemical signals in small studies or community reports, but large, controlled trials at these low doses demonstrating consistent functional benefit at these lower doses are lacking.

Evidence suggests dose-dependent effects on some biomarkers, but a definitive linear dose–response for clinical endpoints in humans has not been established.

From the limited in vivo data and mechanistic reasoning, effective doses of SS-31 from 5 mg day to 40 mg day, continuous, daily seem reasonable.

SS-31’s effects are occupancy-dependent and reversible, i.e. when the drug is gone, the benefit fades.

Mechanistically, SS-31 enables more efficient mitochondrial function while on
board, it doesn’t offer lasting repair. There is no justification for on/off cycling. All the human clinical trials used continuous daily dosing with no pulses or on/off pattern.

 

[FartfulCodger]

A YouTuber named Nick Trigili just made a video on this subject today: "Everyone is using the GLOW stack wrong"

He advocates using the components separately because of dosing and half-life differences. His reasoning is solid; I just can't vouch for the facts behind it.

 

[Camlbacker]

Oi pessoal.

Sou novo por aqui e estou pesquisando sobre GHK-Cu. Estou considerando usar 2mg diariamente por um período prolongado.

Notei que algumas pessoas recomendam suplementar com zinco juntamente com GHK-Cu para otimizar os resultados devido ao teor de cobre. Qual a dosagem que você está usando? Se é que está usando.

Bem-vindo.

Esse esquema de dosagem parece razoável por até cerca de 12 semanas, com um intervalo de 4 semanas entre os ciclos. Adicionar zinco, como mencionou, também seria uma medida sensata para equilibrar o excesso de cobre.

@PEP-Guardyola

​

 

[Poobert]

I just got everything separately. I’m excited to see how these peps affect me since I’ve only been on Reta so far

 

[Rickcaps]

What do you all think about ghkcu vs ahk cu?

 

[amosmylove]

This is my conclusion as well! 🤣

 

[amosmylove]

What do you all think about ghkcu vs ahk cu?

I'm not familiar with ahkcu, so no help there. I will say my skin (face acne) has greatly improved since a couple weeks after starting my first ghkcu cycle. I also started using a blue and red light therapy mask at the same time so I can't definitively say which is most improving it but I'm really pleased regardless so I'll keep up both.

 

[Rickcaps]

I'm not familiar with ahkcu, so no help there. I will say my skin (face acne) has greatly improved since a couple weeks after starting my first ghkcu cycle. I also started using a blue and red light therapy mask at the same time so I can't definitively say which is most improving it but I'm really pleased regardless so I'll keep up both.

What's your dosage like? And the cycle ?

 

[amosmylove]

What's your dosage like? And the cycle ?

I'm doing 2.5 mg daily for the entire 100mg vial. Roughly 40 days/6 weeks on. Then a few week break and back on. I'm waiting on my first kit of ghcku to arrive and then I'll have to wait on testing so it'll line up okay time-line wise. From what I've read it's about 3 cycles in is when you truly notice skin rejuvenation/ legit appearance improvements. I have nice body skin but still get face acne so I'm looking forward to a clear complexion.

 

[Rickcaps]

I am almost at 2.5 months of klow and I see my skin healing. Acne scars are slowly filling up.

Next up I'm researching a blend of ahk and ghk or half doses split 12 hours.

 

[CNCCurrency]

I am almost at 2.5 months of klow and I see my skin healing. Acne scars are slowly filling up.

Next up I'm researching a blend of ahk and ghk or half doses split 12 hours.

I thought Ahk is better as topical for hair growth, don't think I have seen it forsale other than as a raw peptide?

https://pep-pedia.org/peptides/ahk-cu

 

[Rickcaps]

I thought Ahk is better as topical for hair growth

What I'm discovering is that it's both topical and subcutaneous. Ahk cu however has deeper penetration.

 

[CNCCurrency]

What I'm discovering is that it's both topical and subcutaneous. Ahk cu however has deeper penetration.

Where are you getting Lyophilized Ahk? Don't ever recall seeing it forsale. Or are you going to inject raw ahk?

 

[Rickcaps]

Where are you getting Lyophilized Ahk? Don't ever recall seeing it forsale. Or are you going to inject raw ahk?

Not sure if I can write suppliers name here as it will go against the forum rules but yes there are people offering it.