Chronic Pain

Elocin

Elocin

GLP-1 Apprentice
Member Since
Apr 27, 2026
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Canada
From researching, I know that BPC-157, TB-500 and KPV are all peptides that can help with pain. I’m just not sure which one I should try first, as a newbie. Since I have a few different issues going on.
I suffer with Chronic pain. I have a few disc bulges and small tears in my c-spine, and have been undergoing testing for suspected MS. On top of all that, I was hit by a vehicle this past January, as a pedestrian. 🙃 which, obviously, aggravated my neck issues and new back pain.
If I didn’t have bad luck, I would have no luck at all. lol. But any experiences or recommendations would be greatly appreciated!!
 
Elocin said:
From researching, I know that BPC-157, TB-500 and KPV are all peptides that can help with pain. I’m just not sure which one I should try first, as a newbie. Since I have a few different issues going on.
I suffer with Chronic pain. I have a few disc bulges and small tears in my c-spine, and have been undergoing testing for suspected MS. On top of all that, I was hit by a vehicle this past January, as a pedestrian. 🙃 which, obviously, aggravated my neck issues and new back pain.
If I didn’t have bad luck, I would have no luck at all. lol. But any experiences or recommendations would be greatly appreciated!!
Click to expand...
Get KLOW and take them all at one time. While yes, it is a tad expensive, its still cheaper than buying the 4 components individually.
 
MikeyMike said:
I was just reading about ARA-290, seems like this might be a good solution for you. I haven't tried it, but have seen a few sources say it is great for chronic pain and fatigue.
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This is one I haven’t come across yet. Thank you! I am going to look into it!
 
MsGizmo said:
Get KLOW and take them all at one time. While yes, it is a tad expensive, its still cheaper than buying the 4 components individually.
Click to expand...
I wouldn't recommend for a first timer. Its possible you could have a reaction or side affects to one and you will have no way of knowing which one caused it. Plus they all have different dosing.
 
As a person who has had bulgind discs that ruptured and subsequent surgery to repair and fuse my cervical spine...there is only so much peptides can do with that. Sorry you are dealing with that, no fun at all.
That being said, perhaps some peptides may help with the inflammation and give you some relief. I have some residual issues from my spine and BPC157 and TB500 do seem to help (I actually do an individual KLOW stack, if you do, onboard one at a time and slowly give each pep time, so you can gauge your reaction).
I'm going to try cartalax her soon as well. No matter, structural damage is so different from soft tissue injuries...I hope you can find some relief.
 
Elocin said:
From researching, I know that BPC-157, TB-500 and KPV are all peptides that can help with pain. I’m just not sure which one I should try first, as a newbie. Since I have a few different issues going on.
I suffer with Chronic pain. I have a few disc bulges and small tears in my c-spine, and have been undergoing testing for suspected MS. On top of all that, I was hit by a vehicle this past January, as a pedestrian. 🙃 which, obviously, aggravated my neck issues and new back pain.
If I didn’t have bad luck, I would have no luck at all. lol. But any experiences or recommendations would be greatly appreciated!!
Click to expand...
Consider prednisone. Fixes my back, sciatica and tingling fingers from a neck disc temporarily.... it treats the inflammation and irritated nerves which will resolve the pain and not mask it. Research it first, you cant stay on it indefinitely, raises blood sugar and theres a protocol to follow.
 
Airborne Daddy said:
Consider prednisone. Fixes my back, sciatica and tingling fingers from a neck disc temporarily.... it treats the inflammation and irritated nerves which will resolve the pain and not mask it. Research it first, you cant stay on it indefinitely, raises blood sugar and theres a protocol to follow.
Click to expand...
For osteoarthritis and some systemic inflammation, a family member was just put on prednisone for a month, starting at 15 mg and tapering down to 2.5 mg. Prescribed by a rheumatologist.
 
Calm Logic said:
For osteoarthritis and some systemic inflammation, a family member was just put on prednisone for a month, starting at 15 mg and tapering down to 2.5 mg. Prescribed by a rheumatologist.
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spikes glucose and promotes osteoporosis (unsure of spelling) but only thing thats worked for me...an anti inflammatory that peptides cant compete with imo....
 
Prednisone has a very long list of side effects, but is still often used in medicine for it's extremely effective anti inflammatory effects for a large number of problems from asthma to autoimmune disorders. But the adverse effects are a serious issue, and you stop making cortisol your natural version of it and you can get very unwell or even die, if on it for a while and then you suddenly stop. So absolutely not a self treatment option, its use requires clinical judgement as to where the benefits outweigh the costs, and requires a Doctor for short term use and a specialist for longer term use.
GLP drugs actually have a huge amount of preclinical evidence that they reduce inflammation and pain and a lot less human trial evidence, but there is some, that they can reduce both chronic pain and inflammation. Out of the peptides on the typical vendor list , it probably has the best human trial evidence of being useful for chronic pain or inflammation.
 
Airborne Daddy said:
Consider prednisone. Fixes my back, sciatica and tingling fingers from a neck disc temporarily.... it treats the inflammation and irritated nerves which will resolve the pain and not mask it. Research it first, you cant stay on it indefinitely, raises blood sugar and theres a protocol to follow.
Click to expand...
Prednisolone destroys your bones long term. I have lupus and refuse to take it long term. I do like 3 week tapers.
 
Prednisone/cortisone of any type is a big no-no for me. In this case, minus the MS, I would focus on debriding the disc if not outright removal and fusing. Then you can use peptides and even stem cell therapy
 
Elocin said:
From researching, I know that BPC-157, TB-500 and KPV are all peptides that can help with pain. I’m just not sure which one I should try first, as a newbie. Since I have a few different issues going on.
I suffer with Chronic pain. I have a few disc bulges and small tears in my c-spine, and have been undergoing testing for suspected MS. On top of all that, I was hit by a vehicle this past January, as a pedestrian. 🙃 which, obviously, aggravated my neck issues and new back pain.
If I didn’t have bad luck, I would have no luck at all. lol. But any experiences or recommendations would be greatly appreciated!!
Click to expand...
That's a lot - sorry you're going through all this. IMO, I'd start with KPV. Not only is it cheap, it has such a wonderful broad-range impact in the body, and it's a super-durable peptide. You can SQ it, take it orally, hell, I think they even make it in suppository form for targeting IBS, etc. (don't hold me to that, but I think I read it somewhere in a Pubmed paper).

I was mixing my own GHK-cu and KPV, which was a great daily pin, and I took another pin of KPV in the AM too, so my daily was 4 mg GHK-cu and 1 mg KPV. I ran out of KPV and haven't gotten around to ordering more after my last Tirz and Reta buying spree, but I need to.
 
Unfortunately, I have a GP who doesn’t like to “refer out”, and has dropped the ball on more than one occasion.
The MS testing has been long and frustrating. My next recall MRI is in August. Last time, he “forgot” to send a repeat of my cspine, so I have no idea what the damage looks like now, as last was done in 2024. But he sure likes to send me for X-rays, that don’t show anything, of course 🙃. But we have a massive shortage of Family doctors here, so I have to stick with him for now.

Thank you to everyone for all your suggestions! I really appreciate all your responses. I have some researching to do!

❤️❤️❤️
 
MikeyMike said:
I was just reading about ARA-290, seems like this might be a good solution for you. I haven't tried it, but have seen a few sources say it is great for chronic pain and fatigue.
Click to expand...
ARA is GREAT, but a couple things to be mindful of. Most ARA vials are 10mg, or 16mg. The usual dose is 4mg and can take 3-4 weeks to feel any relief. You'll be using a vial every 4 days (on 16mg vials) and "protocol" states to use only for 30 days. It can get expensive to feel relief.
 
Elocin said:
From researching, I know that BPC-157, TB-500 and KPV are all peptides that can help with pain. I’m just not sure which one I should try first, as a newbie. Since I have a few different issues going on.
I suffer with Chronic pain. I have a few disc bulges and small tears in my c-spine, and have been undergoing testing for suspected MS. On top of all that, I was hit by a vehicle this past January, as a pedestrian. 🙃 which, obviously, aggravated my neck issues and new back pain.
If I didn’t have bad luck, I would have no luck at all. lol. But any experiences or recommendations would be greatly appreciated!!
Click to expand...
KPV, KPV and did I mention: KPV? 😀
 
Elocin said:
Unfortunately, I have a GP who doesn’t like to “refer out”, and has dropped the ball on more than one occasion.
The MS testing has been long and frustrating. My next recall MRI is in August. Last time, he “forgot” to send a repeat of my cspine, so I have no idea what the damage looks like now, as last was done in 2024. But he sure likes to send me for X-rays, that don’t show anything, of course 🙃. But we have a massive shortage of Family doctors here, so I have to stick with him for now.

Thank you to everyone for all your suggestions! I really appreciate all your responses. I have some researching to do!

❤️❤️❤️
Click to expand...
And thats the problem with public healthcare like Canada and the NHS in the UK. You dont own your own body. I would look into medical tourism very seriously.
 
Elocin said:
This crossed my mind.. but was worried about possible reactions.
Click to expand...
While yes, KLOW can give you an injection site reaction .. its not all that bad. I will GLADLY trade a tiny sore spot on my skin every now and again for the amount of pain reduction I get from it. I mean before I discovered KLOW I let them inject cortisone directly into my knee cap trying to get relief from the pain. KLOW has done a MUCH better job and I just inject that into my belly fat. Its cheaper too. That one cortisone shot cost me $250 and I had reduced pain for about 3 months. I bought my kit of KLOW for less than $500 and I have been using it for nearly a year and still have 4 unused vials of it.
 
I second the recommendation to look into medical tourism. Safely sourced stem cell treatments can be life-changing for things like bulging/ruptured discs. Mexico tends to be much more reasonably priced and maybe more accessible for you than Bangkok.
Any good clinic will run or recommend a battery of tests to make sure there's no cancer or adverse conditions that could proliferate with stem cells.
Those locations also have access to less expensive PRP treatments, which are a great companion for stem cell treatments.
 
Crumplestiltskin said:
I second the recommendation to look into medical tourism. Safely sourced stem cell treatments can be life-changing for things like bulging/ruptured discs. Mexico tends to be much more reasonably priced and maybe more accessible for you than Bangkok.
Any good clinic will run or recommend a battery of tests to make sure there's no cancer or adverse conditions that could proliferate with stem cells.
Those locations also have access to less expensive PRP treatments, which are a great companion for stem cell treatments.
Click to expand...
Yeah I had a PRP +stem cell treatment in India
 
Smiter said:
And thats the problem with public healthcare like Canada and the NHS in the UK. You dont own your own body. I would look into medical tourism very seriously.
Click to expand...
Crumplestiltskin said:
I second the recommendation to look into medical tourism. Safely sourced stem cell treatments can be life-changing for things like bulging/ruptured discs. Mexico tends to be much more reasonably priced and maybe more accessible for you than Bangkok.
Any good clinic will run or recommend a battery of tests to make sure there's no cancer or adverse conditions that could proliferate with stem cells.
Those locations also have access to less expensive PRP treatments, which are a great companion for stem cell treatments.
Click to expand...

This is something I didn’t know about. I mean, I’ve heard of people going to Mexico or Turkey, as an example, for cosmetic surgeries. Didn’t even think about anything else outside of that.
You both gave me something to think about.
 
Elocin said:
This is something I didn’t know about. I mean, I’ve heard of people going to Mexico or Turkey, as an example, for cosmetic surgeries. Didn’t even think about anything else outside of that.
You both gave me something to think about.
Click to expand...
You're welcome. I do accept Visa and Paypal.. Oh yeah, fix the herniated discs, then look for PRP+stem cell. I did mine in Regencare hospital, Cochin, India.
 
Some possibilities, but not one magic bullet.

Tirzepatide is pretty well know for anti inflammatory properties and many find relief chronic pain.

KLOW supports healing, collagen, etc

HGH, likely 2 IU daily. After 6ish werks get igf1 and z score tested. Aim for z score of 2.

20grams daily if good collagen supplement. Research had been meh for skin quality, but pretty solid for joints around the 12-20 week mark.

Now the most Grey area, Anavar. Mild oral steroid. Im assuming you're female based on avatar. Can only run so much for so long before worrying about virilization. But promising for MS and healing in general.

I think a combo of the above with good physical therapy could do wonders. Problem is hard to find a good physical therapist that isn't 2 decades behind.
 
Elocin said:
This is something I didn’t know about. I mean, I’ve heard of people going to Mexico or Turkey, as an example, for cosmetic surgeries. Didn’t even think about anything else outside of that.
You both gave me something to think about.
Click to expand...
I hope you find something that works for you! I may be biased in my experience, but I've found even more basic medical care (checkups, etc) have had much higher quality doctors and facilities in Mexico.
A LOT of places now do video consultations, which can be extremely helpful in determining if you should/can seek medical care there.

Some other medical tourism considerations:
Dental work (especially big-ticket items like implants)
Surgeries; even with insurance, the premiums could be way higher than what is quoted. (And as I mentioned, you'll likely get a far more luxurious experience outside of your home country).
Radiology; out of pocket MRIs in Mexico tend to around $100, Xrays can be $30 ish, etc...
Other regenerative support like nutritional IVs
Prescriptions can be much cheaper; most do require a doctors note, but it can be fairly easy to meet with a doctor.
 
While stem cell therapies have a lot of interesting and promising research, they are not approved as therapies, or proven to be safe in humans at this time. ( except I think one for heart attacks in japan ) The obvious risk is of malignancies developing in the long term.
 
gusterbuster said:
Some possibilities, but not one magic bullet.

Tirzepatide is pretty well know for anti inflammatory properties and many find relief chronic pain.

KLOW supports healing, collagen, etc

HGH, likely 2 IU daily. After 6ish werks get igf1 and z score tested. Aim for z score of 2.

20grams daily if good collagen supplement. Research had been meh for skin quality, but pretty solid for joints around the 12-20 week mark.

Now the most Grey area, Anavar. Mild oral steroid. Im assuming you're female based on avatar. Can only run so much for so long before worrying about virilization. But promising for MS and healing in general.

I think a combo of the above with good physical therapy could do wonders. Problem is hard to find a good physical therapist that isn't 2 decades behind.
Click to expand...
Thank you so much!!
 
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