End of the vial issue.

ultima thule

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Today was finishing Reta vial. Had exact amount of liquid inside which was 0.1ml. The problem was I couldn't draw all the liquid, and eventually syringe was able to get 0.08ml only. At first thought it might be just all what's left, due to some loss while taking the previous doses, but have seen there is still that few missing drops in the vial, but couldn't reach them by the syringe. Do you have any efficient method to suck up all the leftovers from the ending vial?
 
Not sure if you do this already but whenever im getting to the last dose of my vials, I draw the needle back as far as I can from the rubber stopper, just enough to where its pierced and into the vial but not all the way in and make sure the vial is upside down so I can draw all of it out. Usually I get about everything out or if anything at most a drop would be left in there so nothing substantial.
 
Not sure if you do this already but whenever im getting to the last dose of my vials, I draw the needle back as far as I can from the rubber stopper, just enough to where its pierced and into the vial but not all the way in and make sure the vial is upside down so I can draw all of it out. Usually I get about everything out or if anything at most a drop would be left in there so nothing substantial.
That's exactly what I did. Was pumping by syringe up and down, several times, but no joy at the end...was thinking about opening the vial, and try to draw it directly, but had no time for that due to the morning rush...
 
That's exactly what I did. Was pumping by syringe up and down, several times, but no joy at the end...was thinking about opening the vial, and try to draw it directly, but had no time for that due to the morning rush...
You know honestly now that I think about it, I wonder if this is maybe the reason as to why almost every COA i see for a peptide is usually overfilled, even if its slightly?
 
Suck some as much air as your solution in the syringe first. Then turn the vial upside down. Needle in the vial until it reaches the space on the solution and pump the air in that space. Pull the needle completely back to the bottom, while you hold the pump pushed inside. Then release the pump. Air pressure inside will push all the solution in your syringe.
 
You know honestly now that I think about it, I wonder if this is maybe the reason as to why almost every COA i see for a peptide is usually overfilled, even if its slightly?
Yeah, but at the end of the day, that last dose, with missing a few drops is still lower than the all previous doses from the same vial.
 
Yeah, but at the end of the day, that last dose, with missing a few drops is still lower than the all previous doses from the same vial.
If you are that concerned with the few pennies in there and dont want to take a little from your next vial, put another .2 ml of BAC in, and will extract 95 percent of what you can’t get out.
 
Not sure if you do this already but whenever im getting to the last dose of my vials, I draw the needle back as far as I can from the rubber stopper, just enough to where its pierced and into the vial but not all the way in and make sure the vial is upside down so I can draw all of it out. Usually I get about everything out or if anything at most a drop would be left in there so nothing substantial.
^ this - will get almost everything out of the vial.
You know honestly now that I think about it, I wonder if this is maybe the reason as to why almost every COA i see for a peptide is usually overfilled, even if its slightly?
The amount of powder you get in mg quantities is so minuscule that adding a little more to reach the desired concentration often ends up in overfilling. The powder in the vial is mostly filler. The actual active content is tiny.

Imagine being in a lab, weighing out the ingredients, noticing it's slightly under, and you add just a tiny amount more but it's over. It's better to keep it there than try to take more out to get it exactly to the goal weight (which will never happen anyway).
 
If you are that concerned with the few pennies in there and dont want to take a little from your next vial, put another .2 ml of BAC in, and will extract 95 percent of what you can’t get out.
Don't be silly, it is not about a few pennies lad. It is a bout the exact dose. I had another vial reconstituted the day before. So if I draw the missing liquid from the new vial, I'm still in the same spot with that. If I predicted I'm not able to suck up the vial dry, would do it your way....
Just thinking... next time will open the vial if I meet the same issue 🤨
 
Exactly what @RicFlair said. You got to pull the needle back to the very end of the stopper while holding the vial upside down. The needle needs to be just barely inserted into the vial. In that position you’ll like draw a lot of air, but that’s okay, just expel the air when everything has been extracted.
 
Don't be silly, it is not about a few pennies lad. It is a bout the exact dose.

When I have a partial dose in a vial I inject it, then pull the remainder from the new vial. I’m a big fan of purposeful accuracy. Fill variance isn’t something I concern myself with since I can’t control it and can’t meaningfully measure it for each vial.

With that variable uncertainty in literally every vial, I don’t care about .02ml variance…. If I only had .08ml pulled from the last vial, I’d toss the syringe and the vial and pull the full dose from the new vial.



People do remove the top and go through efforts to vacuum every drop. To me, it’s not that serious, but admittedly I have an abundance of peptides.


This is a typical vestigial remains in a discarded vial. I can’t be bothered to care about that.

1779705091480.webp
 
Exactly what @RicFlair said. You got to pull the needle back to the very end of the stopper while holding the vial upside down. The needle needs to be just barely inserted into the vial. In that position you’ll like draw a lot of air, but that’s okay, just expel the air when everything has been extracted.
Gonna give it a try next time than. Actually it makes sense. I'm using short needles, but anyway the needle's hole could be slightly above the leftovers...it was an early morning and wasn't prepared for that, so didn't play all angles
 
If you are that concerned with the few pennies in there and dont want to take a little from your next vial, put another .2 ml of BAC in, and will extract 95 percent of what you can’t get out.

This is the way.
 
Alternatively, could you use a longer needle? The 1.5" I use to recon and filter gets every last drop.

Like you @ultima thule - it's not the pennies I care about it's the always being 1/2 step behind to have to recon and filter at 5am.
Devils advocate says to recon another vial before you’re at the last dose and forgo the 5am hassle.
Guys, like I said above, another vial reconstituted the day before, was ready to use. Cuz 0.1ml left in the first one, and I needed 0.2ml. So I thought I'm well prepared, but there's always something to surprise you at the early morning 😁
 
I pry off the vial cap and use a syringe that is narrow enough to pass through the opening and with a needle long enough to reach the bottom of the vial.
 
When I have a partial dose in a vial I inject it, then pull the remainder from the new vial. I’m a big fan of purposeful accuracy. Fill variance isn’t something I concern myself with since I can’t control it and can’t meaningfully measure it for each vial.

With that variable uncertainty in literally every vial, I don’t care about .02ml variance…. If I only had .08ml pulled from the last vial, I’d toss the syringe and the vial and pull the full dose from the new vial.



People do remove the top and go through efforts to vacuum every drop. To me, it’s not that serious, but admittedly I have an abundance of peptides.


This is a typical vestigial remains in a discarded vial. I can’t be bothered to care about that.

View attachment 24628
Same.
Devils advocate says to recon another vial before you’re at the last dose and forgo the 5am hassle.
I always have one mixed a few days before when getting close to the last dose. Tracking the proposed (recon calc) amount of doses helps to know I'm getting close.
 
The problem stems from the amount of water used for reconstitution and the accuracy of the syringe.

For example, if you use 3 ml for 10 doses of 0.3 ml, and you end up with 0.02 ml (2 units) left over, that amounts to a 6-7% loss on the dose. In your case, the loss is closer to 20%. That’s why lab pens often have 0.6 ml per dose, it’s more precise.

3 or 5ml syringes are harder to read than 1ml syringes. When I use only a small amount of water (0.5 to 1.2 ml), I use an insulin syringe.

In short, dilute more and use the syringe size closest to the volume you need for reconstitution.

You'll have to find your sweet spot between ease of reconstitution and the volume you want to inject. For 10 units, I use pens. I just received a Gansulin: it's my new favorite toy
🙂
 
Today was finishing Reta vial. Had exact amount of liquid inside which was 0.1ml. The problem was I couldn't draw all the liquid, and eventually syringe was able to get 0.08ml only. At first thought it might be just all what's left, due to some loss while taking the previous doses, but have seen there is still that few missing drops in the vial, but couldn't reach them by the syringe. Do you have any efficient method to suck up all the leftovers from the ending vial?
You can use a mixing syringe with a 1 1/2 inch needle. That will reach the bottom of the vial and you can draw everything out.
 
At least explain why.
Why are you changing the original recon amount of BAC? Most of us don't use 3ml or 5ml syringes. My Easy Touch syringes for .05 and 1ml depeding on the shot size and barely lose anything, I've checked, they hardly hold anything. I do BAC purge after filtering. Just my opinion.
 
As I said, generally I use a 1ml syringe for reconstitution. I’m not talking about injections. My point is that 3ml syringes aren’t precise enough for adding the BAC to the vial if one wants 1 ml or more.

What I'm comparing is a 1 ml reconstitution to make 10 doses x 10 units versus a 3 ml reconstitution to make 10 doses x 30 units. Since the concentration is lower in the second case, the volume lost remains the same, but the amount lost is three times less.
 
Well, that's your call. I use 3 and 5ml for that, as I recon from R24 to R60. I have some R140 coming, and that'll be the 5ml. Even a R30, I add 3ml BAC and use the 5ml, as that 3 ml is full. Filtering is another animal. What size vial mg are you mixing?
 
If you are that concerned with the few pennies in there and dont want to take a little from your next vial, put another .2 ml of BAC in, and will extract 95 percent of what you can’t get out.
Would you put one syringe into two vials or do two separate pins?
 
Well, that's your call. I use 3 and 5ml for that, as I recon from R24 to R60. I have some R140 coming, and that'll be the 5ml. Even a R30, I add 3ml BAC and use the 5ml, as that 3 ml is full. Filtering is another animal. What size vial mg are you mixing?
For the R20, I now use 0.6 ml of BAC, which I transfer to a vial for an injection pen. This allows me to limit each dose to 0.3 ml (so 10mg). I don't like to inject too much BA. Reta dissolves easily up to 80 mg/ml, which leaves some margin.
 

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