I just had labs taken for lgf1 and received my score. It’s about a third for my age. I’d like some info on those who tracked their igf1 level before and after usage of either one of the following cjc/ipa , tesa, sema, Igf-lr3 , hgh. Time, dosage, cycle, and what increase or decrease in your score. I know cases are gonna vary widely but would like a gauge on percentage of increase.
Igf -1 level (score ) before and after
- Thread starter Memo85
- Start date
WeezinDaJuice
GLP-1 Enthusiast
Blood test next Monday after 8 weeks on CJC/Ipa, 5 days nightly fasted, weekends off. Hoping for a IGF-1 improvement, but will report back either way.
Twowheelr2
GLP-1 Enthusiast
Before starting IgF-1 was 102. After 37 daily doses of 2mg Tesa/ 525mcg Ipa I cycled off due to fluid retention and numb tingling arms and hands. Retested at that point and my IGF-1 was 96!!! Went down. The Z score was -0.1.
I’m not sure if my “fasted state” was adequate or my cycle was long enough to bring about GH increase. BTW I’m almost 75 and have resumed another round of Tesa/ipa. However now I’m dosing in the AM. No fluid problems so far.
CNCCurrency
GLP-1 Specialist
What are your numbers?
sfkid
GLP-1 Enthusiast
I didn’t receive a z score but I got a 147 ng/ ml 46year old male. I have to call them to get the z score.
chewonmysac
GLP-1 Enthusiast
50 days 2 mg Tesamorelin AM fasted
Got results last week.
IGF-470
Z-score +3.0
Took a much-needed break as the carpal tunnel and joint pain were pretty annoying.
Flushed out 4lbs of water in 6 days. My best weight loss week since the start. Down 102lbs. BMI is finally back to 25. Probably last seen in the 9th grade😀. Results achieved. Will run again by the end of summer at a slightly lower dose.
Got results last week.
IGF-470
Z-score +3.0
Took a much-needed break as the carpal tunnel and joint pain were pretty annoying.
Flushed out 4lbs of water in 6 days. My best weight loss week since the start. Down 102lbs. BMI is finally back to 25. Probably last seen in the 9th grade😀. Results achieved. Will run again by the end of summer at a slightly lower dose.
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hotsauceboss
GLP-1 Novice
🚫No Source Discussion🚫
I'm going to get started on this in a week or so when my Tesa/Ipa gets delivered. I did a panel through goodlabs and found my IGF z-score was -1.0. As someone who has been lifting 4 times a week for years and seeing less results than I would have hoped for, I'm hoping that this makes a difference.
Last year I focused on bulking/lifting and was able to get my lifts up to 400DL/350SQ/250BP at around 195lbs BW. Currently I've cut back to 157lbs and haven't tested maxes but I've probably lost a bit of strength.
I'm planning on running 1mg Tesa/. 3mg Ipa daily for about 10 weeks (have a long trip in August). Currently on 3mg Reta/wk and will lower to 2mg.
Would love to get IGF to ~1.0 z-score. If I can keep body weight around the same but recomp I'd be really happy with that.
Last year I focused on bulking/lifting and was able to get my lifts up to 400DL/350SQ/250BP at around 195lbs BW. Currently I've cut back to 157lbs and haven't tested maxes but I've probably lost a bit of strength.
I'm planning on running 1mg Tesa/. 3mg Ipa daily for about 10 weeks (have a long trip in August). Currently on 3mg Reta/wk and will lower to 2mg.
Would love to get IGF to ~1.0 z-score. If I can keep body weight around the same but recomp I'd be really happy with that.
Age sex?
sfkid
GLP-1 Enthusiast
How are you saving money ? Tesa 20mg around 25.00 and HGh 36iu around 15.0!!!
sfkid
GLP-1 Enthusiast
Male 56yrs
What was your starting Igf ? Age?
wildweasel
GLP-1 Apprentice
Late 30's male. This was what I got out of it over 30 days of use.
Doses shown were generally split up 2 or 3 times a day, fasted.
I saw about 50% increase in IGF1 levels.
Doses shown were generally split up 2 or 3 times a day, fasted.
I saw about 50% increase in IGF1 levels.
woundcarping
GLP-1 Specialist
Curious about that as well. I'm seeing around $1/mg on Tesa and $.50/iu on HGH.
chewonmysac
GLP-1 Enthusiast
53m. That was my first time testing for it.
literallylit
Recently Joined
🚫No Source Discussion🚫
Started sermorelin pm for sleep. I think 350 mcg. Ended up adding Tesa (titrated up to 1.5 mg) and .3 ipa in the AM fasting. About 100 days in, tested ifg-1 for the first time (experiencing some slight sides) and had a z-score of 2.6. Mid 40's male. Worked well. Cycled off for rest and about to re-start.
It's very easy, once you focus on z-score and not mgs or ius. Like most, you're focusing on the wrong thing. If I want to keep z-score > +2, then 20mg Tesa will last me 20 days. But 36ius will only last me 9 days because I need at least 4ius to get my z-score that high on exogenous gh.
Dose gh peptides based on your response to them, not on a set quantity.
woundcarping
GLP-1 Specialist
Clearly it’s normal and common knowledge that you need 4iu of HGH to match 1mg of Tesa. Also that curiosity means I’m focused on you “saving so much money” ($1/day).
CNCCurrency
GLP-1 Specialist
Looking forward to the bro science chart that shows this
woundcarping
GLP-1 Specialist
This all started with me being curious how you were saving money with Tesa vs HGH. I'm curious because I have no experience and am learning about IGF-1 and its manipulation.
YOU said YOU need 1mg of Tesa or 4iu of HGH to "keep a z-score >+2" and Tesa saves you "so much money" over HGH.
1mg Tesa= $1
4iu HGH= $2
Thus you're saving $1/day. I'm impressed that's meaningful savings for you.
YOU said YOU need 1mg of Tesa or 4iu of HGH to "keep a z-score >+2" and Tesa saves you "so much money" over HGH.
ChatGPT said:
1mg Tesa= $1
4iu HGH= $2
Thus you're saving $1/day. I'm impressed that's meaningful savings for you.
CNCCurrency
GLP-1 Specialist
In this economy, saving 50% is a big deal to me. I'd rather pay 365/year instead of 730/year for my supply.
wildweasel
GLP-1 Apprentice
Not going to reply to anyone specific here
First, claiming that a secretagogue is going to increase IGF-1 levels more than HGH itself is absolute non-sense, whos supposed to believe that.
Second, Z-Score it not a useful metric to track in this discussion. Z score is age-adjustd standard deviations above or below mean. It's a lot tougher to boost 0 -> 1 than it is 1 -> 2.
You want to follow IGF-1 Levels compared to your personal baseline, thats the useful metric to follow, not Z-score, thats only useful for tracking how prone someone may be to developing acromegaly or some other GH-related disease when compared to the general population.
Tesa was found to increase IGF-1 levels vs placebo by 50% at 1mg and 65% at 2mg: https://pubmed.ncbi.nlm.nih.gov/16052083/
Another Tesa trial examined only 2mg daily dosing and concluded that it increased IGF-1 levels by 85% https://www.nejm.org/doi/full/10.1056/NEJMoa072375
This study on HGH concluded that 2iu led to 70-100% increase in IGF1 levels, and 4iu led to 150-200% inrease in IGF-1 levels: https://pubmed.ncbi.nlm.nih.gov/3288652/
If we assume that 1mg tesa = 2iu hgh in cost, its clear that hgh provides the more cost-effective means of improving IGF-1
First, claiming that a secretagogue is going to increase IGF-1 levels more than HGH itself is absolute non-sense, whos supposed to believe that.
Second, Z-Score it not a useful metric to track in this discussion. Z score is age-adjustd standard deviations above or below mean. It's a lot tougher to boost 0 -> 1 than it is 1 -> 2.
You want to follow IGF-1 Levels compared to your personal baseline, thats the useful metric to follow, not Z-score, thats only useful for tracking how prone someone may be to developing acromegaly or some other GH-related disease when compared to the general population.
Tesa was found to increase IGF-1 levels vs placebo by 50% at 1mg and 65% at 2mg: https://pubmed.ncbi.nlm.nih.gov/16052083/
Another Tesa trial examined only 2mg daily dosing and concluded that it increased IGF-1 levels by 85% https://www.nejm.org/doi/full/10.1056/NEJMoa072375
This study on HGH concluded that 2iu led to 70-100% increase in IGF1 levels, and 4iu led to 150-200% inrease in IGF-1 levels: https://pubmed.ncbi.nlm.nih.gov/3288652/
Tesa 1mg -- +50% IGF-1 Tesa 2mg -- +65%-80% IGF-1 HGH 2iu -- +70%-100% IGF-1 HGH 4iu -- +150%-200% IGF-1 If we assume that 1mg tesa = 2iu hgh in cost, its clear that hgh provides the more cost-effective means of improving IGF-1
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hodlplus
Recently Joined
🚫No Source Discussion🚫
did you start at 2iu immediately and keep dose static? i just got back igf-1 pre hgh, sitting at 201 and z score of .8. I am starting an extremely conservative titration of .5 iu daily since it is my first time working with gh or secretagogues, but given that i have excellent insulin sensitivity as a result of my tirzepatide use, i am wondering if it would make more sense to titrate more quickly. i am also monitoring with a CGM, although i just started so dont even have a meaningful baseline yet (fasting insuling is 5.4 though)
sfkid
GLP-1 Enthusiast
Started at 2 and stayed at. You won't see much increase in insulin at 2iu...
Jesus Christ, man. I didnt know you were a Michelin rated Master Chef. That's some cooking.
Just one question though, even if somatomedin is my favorite hormone, why would someone want to increase it systemically, when there are other viable options out there now? It's the main reason I am so anti-GH. I am really sensitive to it as well. That z-score thing is a concern. Thousands of biohackers have had fluid retention, joint pain, and other issues due to GH-mediated systemic IGF increase, especially without the gear to increase receptor action.. I still remember Sly's Aussie GH scandal during Rambo 4 production. He was so bloated.
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I've tried both hgh and tesamorelin, which is how I was able to compare them for my needs of boosting igf-1 z-score to around +2. You speak in population statistics, which is useless to my n=1 case, and will be useless for others too.
These igf1 increase levels for hgh are AVERAGE numbers, you need to confirm they work for you. Good starting point, but not everyone will have 100% increase on 2iu hgh. Patient population also matters, as the tesamorelin study included only hiv patients, whose igf1 is low compared to healthy population.
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