Ok, I’m bored. And semi addicted. What’s next?
- Thread starter Glp1judd
- Start date
Start digging into gh secretagogues (cjc, Ipamorelin, tesamorelin, etc)
Wait – cagri Is a goopy ooze?! Did I Somehow miss that tidbit in the countless posts I've skimmed about people trying it ... ?
I've had no complaints and literally melted away from tirz over 6 months, but I have to admit I've been doing a ton of research into reta for the past few weeks for these last 20-30ish pounds and im thinking about pulling the trigger soon.
main issue im running into is it seems like reta doesnt have the same anti-inflammatory effects as tirz (completely cured my sleep apena in 3 weeks of 2.5mg) which I want to keep on for life honestly, but stacking the two seems counter-productive even though it seems to be a popular choice
GtownBrown
GLP-1 Member
I didn’t care for Reta—may try it again later for maintenance
DwightTheDelight
GLP-1 Enthusiast
I feel the same way. Completely unimpressed, but willing to give it another try in the future
I can't speak on the rest, but I absolutely hated teso. If I wasn't worried about sending drugs in the mail, I'd just send you a bottle to try.
NolaJen1120
New Member
I've been using Tesofensine since July with 10mg/week of tirz. Tirz was great for losing my first 50 lbs., but then my weight loss pace slowed down by half. For 7 months, I was only losing 0-5 lbs even though I still had 90 lbs to lose. Even on tirz, my metabolism is still a good bit slower than average for my height and weight.
Tesofensine supposedly speeds up your metabolism. Sure seems like it! I lost 6 lbs the first month. Added 2mg/week of reta the second month, but that was the only vial I had to experiment with. I lost 8 lbs that month. I went back to just tirz/tesofensine after that and have been losing 5 lbs/month since.
Tesofensine also adds some extra appetite suppression, but I kept my calories the same. If anything, I've had a little more flexibility in being able to have more calories or carbs sometimes without it hurting my weight loss pace.
It's technically not a peptide and it's in pill form, so I'm not sure if the Chinese peptide companies carry it. I've gotten it from various US labs. I tried it from Solution Peptides first, but then I found it a lot cheaper at Biostrategix. It's normal price at SP is $119 for 30 500mcg pills. The normal price at Biostrategix is $185 for 120 500mcg pills and they have a perpetual 10% discount code that is Rollins10 (not associated with me). I take one 500mcg pill a day, usually in the morning. Some people take 1,000mcg/day.
Now I am here on this forum looking for quality, cheaper options for both tirz and reta. I'm almost to my goal weight (yay!), but I will always need to take a GLP-1. I planning to wean myself off tirz and onto reta. My dream is to open up my diet more once I'm in maintenance and teso/reta will allow me even more calories by speeding up my metabolism. Y'all, I'm only 5'0". I wouldn't be surprised if maintenance for me is only 1100 calories/day. I need all the help I can get, lol!
Tesofensine supposedly speeds up your metabolism. Sure seems like it! I lost 6 lbs the first month. Added 2mg/week of reta the second month, but that was the only vial I had to experiment with. I lost 8 lbs that month. I went back to just tirz/tesofensine after that and have been losing 5 lbs/month since.
Tesofensine also adds some extra appetite suppression, but I kept my calories the same. If anything, I've had a little more flexibility in being able to have more calories or carbs sometimes without it hurting my weight loss pace.
It's technically not a peptide and it's in pill form, so I'm not sure if the Chinese peptide companies carry it. I've gotten it from various US labs. I tried it from Solution Peptides first, but then I found it a lot cheaper at Biostrategix. It's normal price at SP is $119 for 30 500mcg pills. The normal price at Biostrategix is $185 for 120 500mcg pills and they have a perpetual 10% discount code that is Rollins10 (not associated with me). I take one 500mcg pill a day, usually in the morning. Some people take 1,000mcg/day.
Now I am here on this forum looking for quality, cheaper options for both tirz and reta. I'm almost to my goal weight (yay!), but I will always need to take a GLP-1. I planning to wean myself off tirz and onto reta. My dream is to open up my diet more once I'm in maintenance and teso/reta will allow me even more calories by speeding up my metabolism. Y'all, I'm only 5'0". I wouldn't be surprised if maintenance for me is only 1100 calories/day. I need all the help I can get, lol!
How much did you take and why did you hate it?
NolaJen1120
New Member
I tried AOD from a US lab last year. I think it was $28/vial for the month and I bought 5 vials. I took 300mcg/daily, I was taking 7.5mg tirz/week also.
The AOD oomphed my weight loss for two months. At that point in time, I was still over 100 lbs overweight and losing 1.5-2 lbs/week on tirz. The AOD added another 0.3-0.5 lb/week.
Then in the third month, there was no more oomph. It was actually my first stall, all around. I took a break from it for about 45 days. It's recommended to take at least a 30-day break from it every 6 months anyway. It didn't add anymore oomph when I went back to it.
Overall, I was glad I tried it. But it definitely wasn't worth the money I paid for the tiny amount of extra weight I lost.
With that said, it works amazingly well for some people. The person who recommended it to me was almost a non-responder with tirz. But she was losing 2-4 lbs/week with AOD. I've read other posts like that also. Along with people who said it did nothing.
I'm planning to place an order for NAD 500 later this week. I bought Lipo-C and NA Semax Amidate (not weight loss related) earlier today. I haven't tried them before and am curious.
The AOD oomphed my weight loss for two months. At that point in time, I was still over 100 lbs overweight and losing 1.5-2 lbs/week on tirz. The AOD added another 0.3-0.5 lb/week.
Then in the third month, there was no more oomph. It was actually my first stall, all around. I took a break from it for about 45 days. It's recommended to take at least a 30-day break from it every 6 months anyway. It didn't add anymore oomph when I went back to it.
Overall, I was glad I tried it. But it definitely wasn't worth the money I paid for the tiny amount of extra weight I lost.
With that said, it works amazingly well for some people. The person who recommended it to me was almost a non-responder with tirz. But she was losing 2-4 lbs/week with AOD. I've read other posts like that also. Along with people who said it did nothing.
I'm planning to place an order for NAD 500 later this week. I bought Lipo-C and NA Semax Amidate (not weight loss related) earlier today. I haven't tried them before and am curious.
DwightTheDelight
GLP-1 Enthusiast
Teso was 0.25 mg per day - I didn't experience any hunger suppression. I actually felt way hungrier than normal for some reason and I was getting angry easily. I only lasted two weeks on it before I gave up.
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I gave up on teso after less than a week because I couldn't tolerate the sleep disruption. Was at 250 mcg in the morning and my sleep was very heavily impacted.
zpped
GLP-1 Specialist
If you get over it. I love teso. But it does screw with my sleep over time so I only take it a couple days every month instead of my Adderall.
notyourrobot
New Member
Teso made me irritable and wrecked my sleep. I had high hopes, but it wasn't the right choice for me. Some people report great success, though, and I'm happy for them.
That seems to be the common starting out Reta experience - more hunger and people eating more, but they report still losing once you get up to the higher doses (6mg+) - lot of people saying youll gain a little back during the transition but itll work itself out on the other side after a couple months on reta. It looks like the reta suppression doesnt really kick in until those higher doses, so thats why so many end up stacking some tirz.
This looks very interesting. Daily injections tho?!
DwightTheDelight
GLP-1 Enthusiast
I should have been more clear, because I was talking about multiple substances in my original comment, but I think I was asked about teso and was answering about that. I'll edit it to make it more clear
I worked up to 4mg of Reta back in June before I stopped, so that could probably use a proper attempt as well.
There is nothing to it if you use an injection pen. I used to think daily sounded bananas, and now i have a morning and evening shot plus two staggered weeklies, it’s all just part of the routine and not a big deal
Sunflower
GLP-1 Enthusiast
You can join the rep ladies subreddit and shop for designer handbags that are supposedly as close in quality to authentic as our grey GLP1s to Mounjaro, etc. And apparently their vendors are similarly capricious and elusive communicators! But they call themselves “cunts” on that sub and downvote basically all questions, so not as welcoming as here 🫢
chmuse
Public Nuisance 🦜🐧🦅🦚🦃🦢🐓🦆🦉
Which one? Repladiesdesigner? A few options turn up
zpped
GLP-1 Specialist
32g 4mm pen needle. Can't even feel it.
You get used to it fast, even without the pen. Or at least I did.
At this point I've got quite a few injections.
TRT every other day
Reta 2x a week
SS-31 5x a week (And adding MOTS-C in next month...)
Tesa/Ipa 5x a week (Cycling off for a bit after I finish this tesa kit)
I'm going to be traveling for work quite a bit over the next few months so I'm grabbing some pens just so I'm not carrying dozens of syringes and vials around with me, but after the first week of frequent pinning, it wasn't too bad.
Damn... too many people saying it wrecked their sleep. This may not be for me.
are you on tirz? does it not also wreck sleep? i was up from 2-430am today, luckily got a couple more hours in the am
Yes... Oz on Sunday, tirz on Weds. No issues with sleep.
Sunflower
GLP-1 Enthusiast
I got kicked out of OGRepladies for asking why they’re all obsessed with the tacky plastic brown LV logo bags 👹 but they’re actually the most user friendly sub I believe.
WagoonLadies has more reviews and fewer “Yassss QUEEN 👛👜👑” bubbly girl energy than OG. But the mods there are extremely picky about questions and assign “homework.”
Both are great for lurking! Also RepLadiesDesigner has by far the most bag photos, but it’s rehoming used reps and way more shilling with few reviews.
chmuse
Public Nuisance 🦜🐧🦅🦚🦃🦢🐓🦆🦉
I used to work next to a LV, after seeing how they operate I'm very fine not even having a counterfeit lmfao.
I once heard a sales guy tell a customer who asked how much a bag cost 'Oh honey, if you have to ask, you can't afford it.' and then WALK AWAY.
I don’t know anything about handbags, but I can say that that sub (wagoon ladies) has the most passionate and articulate bunch I’ve seen on Reddit. Their write ups are several notches above your typical Reddit stuff, whatever they’re doing it keeps the post quality very high.
Thanks for sharing your experience with Tesonfensine. I read this is serotonin/noradrenaline/dopamine reuptake inhibitor. Reads to me like multi mechanism medication like SSRIs and SNRIs (anti depressant).
Have you experienced any mood changes? Any sides?
Also, I'd be careful not to stop it suddenly, and instead reduce the dosage gradually loke it's recommended for such anti-depressants.
You should be jacked! How many cycles of Tesa+Ipa per year do you do? What protocol exactly? If you don't mind sharing.
I started TRT about a month and a half ago and tesa+ipa about a month ago, so not jacked yet. I am lifting 5 days a week though, so hopefully that's on the way.
100mg/week on TRT
2mg tesa/300ish mcg ipa mon-fri
I'm doing bloodwork tomorrow and checking my IGF-1 levels, so I'll be making some more decisions around the GH related stuff based on those details. I've seen a lot of discussion that just doing 2IU of HGH a day produces similar results and is cheaper, so I'm contemplating that.
I've seen some people talking about their doctors prescribing anavar at 10-20mg/day to go with their GLP-1s to help with preserving muscle mass so I'm somewhat curious about that, but my ALT levels aren't great and I'd like to get my blood pressure down a bit more before I look at any sort of AAS. Supposedly doesn't really do much to your liver, lipids, or blood pressure at that low of a dosage, but I'd rather not risk it while any of those aren't already closer to optimal.
zpped
GLP-1 Specialist
Did you get your baseline igf1/insulin/glucose/a1c?
I should have, but nah. I figure my levels will either be in line or they won't, and will go from there.
hotdog!
GLP-1 Enthusiast
I didn't like Reta either. It made me crave sweets which I normally don't care about, but what I really couldn't handle was the skin hypersensitivity. I have sensory issues as is, and this was unbearable even though I worked up slowly from 1 mg for a couple weeks, 2mg for a month, 2.5 for a few weeks then 3mg. Never got better.
I gave up when I read that Reta does have an effect on pain receptors and amplifies the pain/sensitivity loop.
About 15 yrs ago had a very bad case of Reflex Sympathetic Dystrophy, now called Complex Regional Pain Syndrome--basically it's a continual feeling of burning pain in your limbs. Feeling like my foot was constantly on fire for months was enough to make me seriously suicidal, so I'm forever thankful that my pain management doctor successfully stopped that pain loop with a sympathetic nerve block (if I recall). Anyways, I can't risk accidentally tripping that pain loop reaction again, so Reta is a hard no for me.
noggin
New Member
It appears to me that the big issue with these extremely long half life CNS stimulants is the sleep disturbance, which is also the likely culprit of irritability many report. This is probably why dopaminergic drugs on the market today all have half lives around 6-12 hours (Adderall, Vyvanse, XR Ritalin, etc). While on the other hand serotonergic drugs like Fluoxetine exist with a 4-6 day half life (Keep in mind SSRI's are not stimulants)
I have been researching Teso for 3 days now (250mcg, then 500mcg, then another 500mcg today) and I have had extra energy and a little more jittery but overall not too bad, my mood is pretty much the exact same if not slightly worse, but my sleep is like a 4/10. I bet this kind of sleep over the long term would mess you up. Will probably stop researching and take a pill whenever I really need to spend a week sleeping less and focusing more. Probably why this drug never made it off the ground as an anti-depressant or ADHD medication and is instead being studied for weight loss, which I think will likely not succeed due to the sleep issues over the long term. Wish me luck for the next week of sleep!
I have been researching Teso for 3 days now (250mcg, then 500mcg, then another 500mcg today) and I have had extra energy and a little more jittery but overall not too bad, my mood is pretty much the exact same if not slightly worse, but my sleep is like a 4/10. I bet this kind of sleep over the long term would mess you up. Will probably stop researching and take a pill whenever I really need to spend a week sleeping less and focusing more. Probably why this drug never made it off the ground as an anti-depressant or ADHD medication and is instead being studied for weight loss, which I think will likely not succeed due to the sleep issues over the long term. Wish me luck for the next week of sleep!
zpped
GLP-1 Specialist
Yeah, I like teso, but I can't take it for more than a couple days before it starts fucking with my sleep. So I only take it a couple times per month as an alternative to adderall.
Thanks for this. It looks like the pills will stay in the bottle for a bit. I am already an insomniac and cannot afford to get any worse than I am now...
Nikki nik
GLP-1 Specialist
Does tesofensine help with anxiety. How does Adderall help you?
zpped
GLP-1 Specialist
I don't have anxiety. I have attention control issues. I get distracted by anything other than the thing I should be doing.
I guess technically the procrastination eventually leads to anxiety.
Nikki nik
GLP-1 Specialist
Ok thanks.
noggin
New Member
Oh boy it messes with your sleep. On day one of 250mcg I slept a-ok. Next day on 500mcg (~700mcg blood levels) and I slept okayish, definitely slightly noticed sleep disturbance. Day 3 I took another 500mcg (~1200mcg blood levels) and I slept at 6:30am last night 😵💫. Terrible experience. I'm probably gonna deal with this for the next week since I'll still be at 800mcg blood levels by Friday. Hooooo boy at least I have more focus and can push myself more in the gym. Not pushing my levels past 800mcg again.
zpped
GLP-1 Specialist
I took 500mcg for 5 days the first time. Sleep time just kept getting shorter. Now I never use more than a couple days in a row. Started getting better immediately. Very obvious in this graph.
Valerie
GLP-1 Enthusiast
It's a new year ... what did you decide to try ?
What goopy ooze? I've tried to look up the research and can't see anything on it.
Nothing yet. Waiting to see how Nikki’s spicy research goes. 😜
Sunflower
GLP-1 Enthusiast
Funny enough, I felt nothing my whole Teso cycle a few months back. Today is my first day of Mots-C and I actually probably feel something. Like natural, clean energy. Interesting!!
ThePepPlanner
New Member
Did you switch?
I stocked up on reta for the last push on my final 10-15lbs which I heard were the hardest to drop.
Reta made is so easy to reach goal. I'm using Tirz for maintenance because I'm a Tirz-gal but will absolutely use Reta in the future to switch things up.
Nikki nik
GLP-1 Specialist
I have 1 vial of reta I haven't touched. Do you think that 1 can break my tirz stall? 🤷🏽♀️
