Rookie syringe question...

tahiles

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Looking at the syringes I can find, it seems like it would be difficult to accurately judge small doseages like .50 or .75.

Am I missing something?
 
I hate 1mL syringes because of their tick=2 units problem. I now use 0.5mL syringes (tick=1 unit) but will next try the 0.5 unit ticks that some 0.3mL syringes have.

What you might be missing, though, is reconstituting with convenient draws in mind. Next time you reconstitute, determine what works for you now (e.g., 20 units) and at your likely next increase, and plug those into the reverse calculator linked in my signature.
 
tahiles said:
Looking at the syringes I can find, it seems like it would be difficult to accurately judge small doseages like .50 or .75.

Am I missing something?
Click to expand...
[Oops ... the always-amazing @chmuse beat me to this answer! But I'll leave it as I wrote it, for the sake of redundancy.]
Also, and this is CRITICALLY IMPORTANT, it's not clear if you understand the difference between the "units" marked on your syringe and the dosage (usually in mg) that you're aiming for. In short, they have nothing directly to do with one another ... and, in fact, one is a volume measure and the other mass/weight. You create a linkage between the two, at no universal concentration, when you reconstitute.

See the first link in my signature if you're new to this.
 
Thanks for the replies. And yes, I’m new to all this mg vs volume stuff. Using an Ozempic pen that does .25 or .50 doses and cost me almost $400 WITH insurance!

Is there a good primer located in this forum that I can study to try and get up to speed?

Thanks again….
 
tahiles said:
Thanks for the replies. And yes, I’m new to all this mg vs volume stuff. Using an Ozempic pen that does .25 or .50 doses and cost me almost $400 WITH insurance!

Is there a good primer located in this forum that I can study to try and get up to speed?

Thanks again….
Click to expand...
The Ozempic pen is marked in milligrams. (mg) This is a mass measurement and how you should record your dosage. When using a syringe you can only measure volume which we usually reference as either milliliters or insulin units. 1.00ml = 100 units or 0.01ml = 1unit.

In order to draw your desired dosage, you need to know the concentration. This is measured in mg per ml, or how many milligrams of the drug are dissolved into 1 milliliter of water. i.e. 20mg with 2ml is 10mg/ml and 0.50mg at that concentration would be 0.05ml (or 5 units).

If you don't absolutely understand everything I just said, you have some studying to do. And definitely don't inject anything without having someone double check you work.
 
zpped said:
The Ozempic pen is marked in milligrams. (mg) This is a mass measurement and how you should record your dosage. When using a syringe you can only measure volume which we usually reference as either milliliters or insulin units. 1.00ml = 100 units or 0.01ml = 1unit.

In order to draw your desired dosage, you need to know the concentration. This is measured in mg per ml, or how many milligrams of the drug are dissolved into 1 milliliter of water. i.e. 20mg with 2ml is 10mg/ml and 0.50mg at that concentration would be 0.05ml (or 5 units).

If you don't absolutely understand everything I just said, you have some studying to do. And definitely don't inject anything without having someone double check you work.
Click to expand...

Thanks for all the help!

This may be an over-siplification so please correct me if I'm wrong.

If I'm getting 5mg vials and want a dose of .5mg than I should inject 1/10 of the amount of BAC water I add to the vial. The dose should be just a hair short based on volume of liquid displaced by volume of dissolved solids.

If I then go the .75 dose, 1.5/10 units injected, then 1.00 mg would be 2/10.

I think this is correct, if not please correct me?
 
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tahiles said:
Thanks for all the help!

This may be an over-siplification so please correct me if I'm wrong.

If I'm getting 5mg vials, and fill them with 10 units of BAC water, and want a .5mg dose I just draw one unit for injection? Should be just a hair short based on volume of liquid displaced by volume of dissolved solids.

If I then go the .75 dose, 1.5 units injected, then 1.00 mg would be two units.

I think this is correct, if not please correct me?
Click to expand...
Correct but I wouldn't do 1 and 1.5 units...use more bac like 50 units to 5mg would make every 10 units = 1mg... so 5 units .5, assuming it's semaglutide and u end up doing 2mg, that's 20 units.... much easier than counting lines, everything would be increments of 5 instead of 1.... personally I would go 100 units (1cc) bac to 5mg making every 20 units= 1mg.... if ur gonna be doing low doses. .5mg is 10 units and .75 is 15 units.
 
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Airborne Daddy said:
Correct but I wouldn't do 1 and 1.5 units...use more bac like 50 units to 5mg would make every 10 units = 1mg... so 5 units .5, assuming it's semaglutide and u end up doing 2mg, that's 20 units.... much easier than counting lines, everything would be increments of 5 instead of 1.... personally I would go 100 units (1cc) bac to 5mg making every 20 units= 1mg.... if ur gonna be doing low doses. .5mg is 10 units and .75 is 15 units.
Click to expand...
Thanks, that makes a lot of sense!
 
Another issue is that your particular batch of lyophilized peptides might have a significant overfill. E.g., although marked 10mg,it might actually lab-test at 12.1 mg

That's just one reason I like to pre-plan my current (and next-step) draw amount in nice round units, and then use the reverse calculator (in my signature) to figure out the non-round, inconvenient amount of bac water to add to the vial.

Don't think primarily in terms of fraction of the vial, or in terms of a fixed concentration ratio ... it's a trap
 
Well I got my 5mg vials. The bottom 1/3
(or so) of the vial looks almost “frosted”. I’m assuming this is the drug itself?

There’s also a white piece of what appears to be plastic that will travel up and down the vial, slowly if coaxed so it seems to be a somewhat snug fit. What’s the purpose of this piece?

1744489265619.jpeg
 
tahiles said:
Well I got my 5mg vials. The bottom 1/3
(or so) of the vial looks almost “frosted”. I’m assuming this is the drug itself?

There’s also a white piece of what appears to be plastic that will travel up and down the vial, slowly if coaxed so it seems to be a somewhat snug fit. What’s the purpose of this piece?
Click to expand...
When Lyophilized, freeze dried basically, the active ingredient, combined with excipients and other fillers, becomes a puck. The puck can move a bit or even break in transport. That looks fine, it is the ingredients, not plastic.
Depending on the contents, when you reconstitute just let it settle or slightly swirl, do not shake as some peptides can be sensitive.
Your BAC water, if that's what this calls for, will turn this all clear. Aim at the side so the vacuum hits slowly.
 
tahiles said:
Well I got my 5mg vials. The bottom 1/3
(or so) of the vial looks almost “frosted”. I’m assuming this is the drug itself?

There’s also a white piece of what appears to be plastic that will travel up and down the vial, slowly if coaxed so it seems to be a somewhat snug fit. What’s the purpose of this piece?

View attachment 6368
Click to expand...
Everything @Skidude said.

Do you have your bac? Do you know how to use a calculator?

@AndyPanda and @indolent both gave you some basic resources you should check out before proceeding. I'm concerned you don't understand what you're doing well enough yet to do this safely.
 
I’m not injecting for a couple of weeks. Did you miss my post above where I asked about injecting 10 units of water into an 5mg vial, and one unit out equaling .5 dosage? Pretty simple method without needing a calculator.
 
tahiles said:
I’m not injecting for a couple of weeks. Did you miss my post above where I asked about injecting 10 units of water into an 5mg vial, and one unit out equaling .5 dosage? Pretty simple method without needing a calculator.
Click to expand...
I believe you would be better off with more BAC, 2 units is not enough. No one here is going to tell you what to do, so you are on your own in this. I will say we are all human and do not want to see someone get hurt.
 
I appreciate that, I really do. How many units would you try to get in one of those tiny vials? I was really surprised at how small they are.
 
@tahiles Just so you understand how off you are in your plan: a drop of water is understood to be 0.05 mL, which converts to 5 units!

1mL = 100 units.

Shoot for a draw (when pinning) that's a numbered tick on your syringe, between 10 and 40 units. Work back from there. The amount of bac water to use for reconstitution in what is probably a 3mL vial should be around 1mL, maybe.

[The custom seems to be to discuss reconstitution in mL, and draws for pinning in units.]
 
tahiles said:
I appreciate that, I really do. How many units would you try to get in one of those tiny vials? I was really surprised at how small they are.
Click to expand...
Take a quick look at this video, and take this slow, you have time to do it right.
The jar holds just over 3 ml. 100 unit/1cc insulin syringe is 1ml

( I was corrected, 1ml=1cc )

I suggest you heed the advice of others and take a few minutes to read/search/watch videos
I HAVE NO IDEA WHO THIS COMPANY IS- JUST A GOOD TUTORIAL
 
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I like this calculator…

primepeptides.co

Peptide Calculator

Calculate the correct syringe dosage for peptides with our easy-to-use peptide calculator. Get accurate unit measurements fast.
primepeptides.co primepeptides.co
 
tahiles said:
I’m not injecting for a couple of weeks. Did you miss my post above where I asked about injecting 10 units of water into an 5mg vial, and one unit out equaling .5 dosage? Pretty simple method without needing a calculator.
Click to expand...

You also didn't seem to know what the vials and their contents would look like. I'm not being rude; I'm making sure you are being safe.

Make sure you check your COA- a vial is often over filled by a large amount as well. So your 1/10 measurement could end up being enough to make you ill.
 
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Well, if you’ve never received them before will you really know what they look like?
 
Skidude said:
Take a quick look at this video, and take this slow, you have time to do it right.
The jar holds just over 3 ml. 100 unit/cc insulin syringe is 1ml

I suggest you heed the advice of others and take a few minutes to read/search/watch videos
I HAVE NO IDEA WHO THIS COMPANY IS- JUST A GOOD TUTORIAL
Click to expand...
you're confused about what a cc is. They are not the same as a unit, they are equal to mL
 
zpped said:
you're confused about what a cc is. They are not the same as a unit, they are equal to mL
Click to expand...
Holy shit.. you are correct.
One milliliter (1 mL) is equivalent to one cubic centimeter (1 cc). Therefore, a 1 mL syringe is also considered to be a 1 cc syringe.
I apologize and retract if I can. I do try to be accurate. That was a major mistake.
Sometimes I am over optimistic in my knowledge.
please..please.. read my disclaimer
 
I try to use enough BAC so that the draw I need is about 20-50 units. This means it fits in a 0.3 cc or 0.5 cc syringe, and it is easy to read the marks. It also means that it will be impossible to make a dumb mistake and accidentally draw up a big overdose, because the dose simply won't fit in the syringe.

Even if I could easily measure and dispense 2 units from a 1 cc syringe, I would not choose to mix it that way.

@tahiles you may enjoy the spreadsheet in my signature as it calculates dose options once you provide the vial mg and BAC mL. (Or it may make no sense to you, I made it for the way my brain works!)

1744565925751.webp
 
How does this report look? Over potency?
 

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