BAC math

[Adavis3053]

So I'm getting Into reconstituing and the math doesn't make sense

I see cases and viles of bac water for 30ml, but most peptides need 1 to 3ml. And the peptide will last a month or longer so you won't need bac again for awhile.....however bac goes bad after 28 days.

I want to buy a case of bac but I'm afraid of wasting them. They'll all go bad by the time I need them again

Has anyone found a way around this?

 

[Skidude]

So I'm getting Into reconstituing and the math doesn't make sense

I see cases and viles of bac water for 30ml, but most peptides need 1 to 3ml. And the peptide will last a month or longer so you won't need bac again for awhile.....however bac goes bad after 28 days.

I want to buy a case of bac but I'm afraid of wasting them. They'll all go bad by the time I need them again

Has anyone found a way around this?

1. The 28 days is once you have pinned-
2. Some people go much longer with proper care and cleaning, as much as 6 weeks+
3. Some people use multiple peps and are using BAC for more than just once a week injection
4. The remaining BAC is "best buy expiry date", many feel it will last much longer than the 1+ yeat on bottle

 

[Iamnew2this]

I use mine for 3 months. It's up to your discretion and what you feel comfortable with. Clean the top before and after each use. That's even if you're going to use it consecutively once you have reconstituted a vial already. When you're all finished, wipe the top and the bottle with a fresh alcohol pad, and start from the very top. Keep it in a cool, dark, and dry place.

 

[Morbius]

Someone found and posted -- somewhere -- material that showed the 28 day lifespan for used BAC was for a commercial environment, with people doing pokes all the time.

If you poke your BAC once and then again a month later and then again a month after that, that's less overall contamination risk than the bottle would have in heavy hospital use. Consequently, many people feel it is an acceptable risk to use their BAC bottles for longer than 28 days.

Everyone has to find their own way on this topic.

 

[Iamnew2this]

Someone found and posted -- somewhere -- material that showed the 28 day lifespan for used BAC was for a commercial environment, with people doing pokes all the time.

If you poke your BAC once and then again a month later and then again a month after that, that's less overall contamination risk than the bottle would have in heavy hospital use. Consequently, many people feel it is an acceptable risk to use their BAC bottles for longer than 28 days.

Everyone has to find their own way on this topic.

I use 25 to 27 ml every 3 months. It's well worth it! I think with this next bottle, I might just use it all. I can fill another vial with the leftover. I've never had a problem.

 

[Batscout]

I use mine for 3 months. It's up to your discretion and what you feel comfortable with. Clean the top before and after each use. That's even if you're going to use it consecutively once you have reconstituted a vial already. When you're all finished, wipe the top and the bottle with a fresh alcohol pad, and start from the very top. Keep it in a cool, dark, and dry place.

I use mine for 10 weeks once opened and I refrigerate it after it has been opened.

 

[Iamnew2this]

I use mine for 10 weeks once opened and I refrigerate it after it has been opened.

Some people refrigerate. I never do and don't think that you have to. Then again, it's what you're most comfortable with. It comes down to personal preference, and comfort levels, I guess.

 

[Morbius]

You are not supposed to refrigerate used BAC and there is a good reason for that. I actually looked up papers digging into BAC sterility to figure this out. It IS non-intuitiuve.

The benzyl alcohol in BAC kills bacteria when they try to divide. Cold slows the rate at which bacteria multiply. So, a chilled BAC bottle can harbor living bacteria that would have died had it been kept at room temperature.

Sorting unused BAC in the fridge would have to be harmless, though I also don't think it is helpful as benzyl alcohol is very stable in a sealed container. But once you poke it -- leave it at room temperature!

 

[indolent]

You are not supposed to refrigerate used BAC and there is a good reason for that. I actually looked up papers digging into BAC sterility to figure this out. It IS non-intuitiuve.

The benzyl alcohol in BAC kills bacteria when they try to divide. Cold slows the rate at which bacteria multiply. So, a chilled BAC bottle can harbor living bacteria that would have died had it been kept at room temperature.

Sorting unused BAC in the fridge would have to be harmless, though I also don't think it is helpful as benzyl alcohol is very stable in a sealed container. But once you poke it -- leave it at room temperature!

How then would the bac water provide any protection against bacterial growth in a refrigerated reconned vial? How is it any different from an opened vial of bac in the fridge?

 

[Iamnew2this]

How then would the bac water provide any protection against bacterial growth in a refrigerated reconned vial? How is it any different from an opened vial of bac in the fridge?

I never thought about it, but that's a good question.

 

[stickfigure]

BAC water doesn't kill bacteria. It prevents it from multiplying. Cooler temperature - slower breeding of bacteria. Recommendation not to store in refrigerator comes from the fact that BA may separate from water at 32F or 0C, but as long as your fridge doesn't go that low, you are good. You could shake the vial before usage to mix it again for extra safety.
I use my bac until it's gone. I usually use 2.5ml at a time, so the whole bottle is 12 punctures. I clean lids every time and have a healthy immune system, so this risk threshold works for me.

 

[Morbius]

How then would the bac water provide any protection against bacterial growth in a refrigerated reconned vial? How is it any different from an opened vial of bac in the fridge?

You are correct... BAC in our vials in the fridge is not working as well as it could! It's a compromise since we are also concerned about stability of the expensive peptide.

There's probably some optimal temperature per peptide that best balances those competing goals, it would be cool to see that investigated.

BAC water doesn't kill bacteria.

To be picky, it definitely does kill but only to a degree. Here's a table from a paper where different agents plus different pathogens were examined. Most pathogens are being reduced over time, even refrigerated. But look at staph! Over 24 hrs of refrigeration, the population is basically unchanged, wow. And this study used 1.5% BA, even stronger than what we use.

Effect of refrigeration on bactericidal activity of four preserved multiple-dose injectible drug products -- Craig R. Lehmann 1977

Since staph is SO robust in refrigerated BAC, and it is SO common on skin, there may be a good argument here for using gloves as extra insurance against introducing staph contamination -- if we are intending to maximize the safe lifespan of our vials.

But, technicalities and speculation aside, my usage policy is the same as yours @stickfigure.