Can Reconstituted Reta be Re-Aliqouted and Frozen

[peptidesupremacy08]

So I was looking at a vendor and their 60mg kits are way cheaper per mg than their 10mg kits. However, I only use about 2.0mg per week, so I would go way over the window to finish the reconstituted peptide, if I were to use that. I seem to be mixed answers from google, reddit, and chatgpt on if I can freeze the reconstituted peptide. My idea would be to dilute with 6ml bac, then portion out into 6 vials at 1ml each and freeze them at -20c in my regular home freezer. Would this destroy/destabilize the peptide? If not, guess I'll just have to pay the extra, but it's not that bad considering it's really not that expensive.

 

[Incognitodoberman]

No, you shouldn’t freeze it. It’ll change the structure of the molecules. I’m so hesitant to purchase those larger quantities too, just for the fact that I couldn’t use them fast enough either. Plus I think the recommendation is once it’s reconstituted you should use it within 8 weeks.

 

[AndyPanda]

So I was looking at a vendor and their 60mg kits are way cheaper per mg than their 10mg kits. However, I only use about 2.0mg per week, so I would go way over the window to finish the reconstituted peptide, if I were to use that. I seem to be mixed answers from google, reddit, and chatgpt on if I can freeze the reconstituted peptide. My idea would be to dilute with 6ml bac, then portion out into 6 vials at 1ml each and freeze them at -20c in my regular home freezer. Would this destroy/destabilize the peptide? If not, guess I'll just have to pay the extra, but it's not that bad considering it's really not that expensive.

There was just a question from someone about freezing another GLP. I think it’s a bad idea. Others will insist it’s fine. I don’t think this is the best place to get a definitive answer on this. You need to decide what your risk level is.

 

[mlke6]

So I was looking at a vendor and their 60mg kits are way cheaper per mg than their 10mg kits. However, I only use about 2.0mg per week, so I would go way over the window to finish the reconstituted peptide, if I were to use that. I seem to be mixed answers from google, reddit, and chatgpt on if I can freeze the reconstituted peptide. My idea would be to dilute with 6ml bac, then portion out into 6 vials at 1ml each and freeze them at -20c in my regular home freezer. Would this destroy/destabilize the peptide? If not, guess I'll just have to pay the extra, but it's not that bad considering it's really not that expensive.

You may not always just be on 2mg a week. At a certain point it might be necessary to up your dose. Those larger mg kits would come in handy there. Would it still be cheaper for you at 2 mg to purchase a 50 or 60 mg kit and use it until you are no longer comfortable using it then throw the rest away?

 

[peptidesupremacy08]

You may not always just be on 2mg a week. At a certain point it might be necessary to up your dose. Those larger mg kits would come in handy there. Would it still be cheaper for you at 2 mg to purchase a 50 or 60 mg kit and use it until you are no longer comfortable using it then throw the rest away?

The problem is that I’m not sure when I should be uncomfortable using the peptide. Everywhere I look claims that 28 days/month is about as long as you should go.

I’m not terribly concerned about getting a subq skin infection, though I probably should be. I get scratches/cuts with bacteria riddled stuff regularly. I also am very precautious with everything—sterilize my work surface, then bring everything out, clean everything with alcohol swaps before doing my injections.

My main issue is with the peptide breaking down and my money basically going down the drain. I’ve read that after the month mark I mentioned, the peptide generally starts to degrade and is therefore not as potent. I can’t seem to find a proper answer on this.

 

[peptidesupremacy08]

No, you shouldn’t freeze it. It’ll change the structure of the molecules. I’m so hesitant to purchase those larger quantities too, just for the fact that I couldn’t use them fast enough either. Plus I think the recommendation is once it’s reconstituted you should use it within 8 weeks.

See even this is different from what I’ve heard, I’m losing my mind not having any concrete info, lol. In my other reply, I mentioned the figure I saw was 4 weeks. A number of other sources recommend not freezing though, so thank you for that!

 

[peptidesupremacy08]

There was just a question from someone about freezing another GLP. I think it’s a bad idea. Others will insist it’s fine. I don’t think this is the best place to get a definitive answer on this. You need to decide what your risk level is.

Yeah, I would say I’m fairly risk averse, I’m just cheap too…thank you though!

 

[mlke6]

The problem is that I’m not sure when I should be uncomfortable using the peptide. Everywhere I look claims that 28 days/month is about as long as you should go.

I’m not terribly concerned about getting a subq skin infection, though I probably should be. I get scratches/cuts with bacteria riddled stuff regularly. I also am very precautious with everything—sterilize my work surface, then bring everything out, clean everything with alcohol swaps before doing my injections.

My main issue is with the peptide breaking down and my money basically going down the drain. I’ve read that after the month mark I mentioned, the peptide generally starts to degrade and is therefore not as potent. I can’t seem to find a proper answer on this.

I've personally used vials past two months. I just figure if it isn't working as well I will just increase dose a little on the bottle. So far I haven't had to. My first bottle was sema and I paid over $50 for it.

 

[lessthanhalf]

I bought 50 mg reta vials , and planned to use it as an add on to 15 mg of tirzepatide, so doses were going to be low. I did not feel comfortable with taking one or two mg doses out and so 25 to 50 needles going in and out as a risk of introducing contamination and then leaving it in the fridge for months seemed a bit risky. So i just reconstituted it, took 1/5 out -10mg and put it in a sterile vial, diluted it to make dosing a bit easier and put the other 40mg back in the fridge. it has bac , so hopefully no bacteria should grow so the main concern would be peptide degradation at fridge temperatures. without spending many hours searching for actually accurate scientific information on retatrutide degradation rates that may not yet be available , I figure it is unlikely to deteriorate at more than a percent or two a month and should be fine for a few months. I personally am not especially concerned about a few percent peptide degradation or leaving it in the fridge for a few months. Freezing it is possibly a better alternative, lower risk of bacterial growth. Repeated freeze thaw cycles definitely causes peptide degradation, but one or two cycles are unlikely to cause more than a few percent degradation. it would probably make more sense to divide it up into vials at the start and only thaw out the vial when you needed it and leave it in the fridge after thawing. It really depends on what you are comfortable with, most of them are overfilled by 5 to 10%, so the dose is not going to be way off if a few percent deteriorate. And bacterial or fungal growth could occur if left in the fridge for months even with bac, I would definitely not be injecting it intravenously , but subcutaneously, you have an immune system and the risk is of an unpleasant and painful abscess, and I can't say I have heard of people complaining about this actually happening from using peptides , so it cannot be common.

 

[nonyabizznez]

Yeah, I would say I’m fairly risk averse, I’m just cheap too…thank you though!

Factor in you're going to save a shit ton on food regardless. I'd buy the kit that suits your needs with minimum risk. A kit lasts a long time and the difference in price is less than one meal at a decent restaurant.

 

[Incognitodoberman]

See even this is different from what I’ve heard, I’m losing my mind not having any concrete info, lol. In my other reply, I mentioned the figure I saw was 4 weeks. A number of other sources recommend not freezing though, so thank you for that!

I'm almost done with the current vial I'm on and I mixed it about 8 weeks ago. Still feeling it, so I know it's working. I also look at mine before I'm ready to use it. Make sure there is no bit of cloudiness. I want it to look crystal clear. If not, I toss it.

 

[peptidesupremacy08]

Factor in you're going to save a shit ton on food regardless. I'd buy the kit that suits your needs with minimum risk. A kit lasts a long time and the difference in price is less than one meal at a decent restaurant.

Yeah I worked the math out last night and the difference btw 10 and 60mg is 45$—for the entire year at my dose. So it really doesn’t matter as much as I thought it did, but I was too focused on the percentages.

 

[peptidesupremacy08]

I'm almost done with the current vial I'm on and I mixed it about 8 weeks ago. Still feeling it, so I know it's working. I also look at mine before I'm ready to use it. Make sure there is no bit of cloudiness. I want it to look crystal clear. If not, I toss it.

This makes sense. When I initially got into here I didn’t realize that the 28 days recommendation is a general pharma recommendation for sterility. I thought it was how long we had until the potency dropped. Thank you!

 

[peptidesupremacy08]

I bought 50 mg reta vials , and planned to use it as an add on to 15 mg of tirzepatide, so doses were going to be low. I did not feel comfortable with taking one or two mg doses out and so 25 to 50 needles going in and out as a risk of introducing contamination and then leaving it in the fridge for months seemed a bit risky. So i just reconstituted it, took 1/5 out -10mg and put it in a sterile vial, diluted it to make dosing a bit easier and put the other 40mg back in the fridge. it has bac , so hopefully no bacteria should grow so the main concern would be peptide degradation at fridge temperatures. without spending many hours searching for actually accurate scientific information on retatrutide degradation rates that may not yet be available , I figure it is unlikely to deteriorate at more than a percent or two a month and should be fine for a few months. I personally am not especially concerned about a few percent peptide degradation or leaving it in the fridge for a few months. Freezing it is possibly a better alternative, lower risk of bacterial growth. Repeated freeze thaw cycles definitely causes peptide degradation, but one or two cycles are unlikely to cause more than a few percent degradation. it would probably make more sense to divide it up into vials at the start and only thaw out the vial when you needed it and leave it in the fridge after thawing. It really depends on what you are comfortable with, most of them are overfilled by 5 to 10%, so the dose is not going to be way off if a few percent deteriorate. And bacterial or fungal growth could occur if left in the fridge for months even with bac, I would definitely not be injecting it intravenously , but subcutaneously, you have an immune system and the risk is of an unpleasant and painful abscess, and I can't say I have heard of people complaining about this actually happening from using peptides , so it cannot be common.

Thank you! This was essentially my idea, but the giant vials, reconstitute, and portion them out and freeze them. Just take one out the night before I need it if it’s frozen. I also share your thoughts on sterility—I cut cuts and scrapes all the time from/in things that are infested with bacteria, so I’d imagine with all the precautions I take, and my immune system, I should be fine with subcutaneous injections. I also intended on filtering when I portion them out, which I think removes a bit more risk. However, given how cheap this stuff is in ab absolute sense, for me, at my dose, and my goals, it probably isn’t worth the headache. I wish I ran the numbers per year before I got deep into trying to figure out if I could freeze reta.