Holy shit...anyone see these Step Up studies?

[Airborne Daddy]

I read last they were going up to 5mg sema but this is really stepping it up! Can our livers and pancreas handle it? Id guess same will happen with tirz....

 

[desinr-gal]

Sema is getting left behind.. they are desperate to catch up

 

[MadisonB]

Sema is getting left behind.. they are desperate to catch up

Right?! And let's make it a higher dose so you have to use more. Feel very big pharma scammy to me.

 

[MsGizmo]

Right?! And let's make it a higher dose so you have to use more. Feel very big pharma scammy to me.

While I am loathe to defend a pharma company .. it doesn't make sense to go through all that trouble to push more of a drug that has a ticking clock on its patent. Unless this would somehow extend that patent.

 

[BooneDonk]

While I am loathe to defend a pharma company .. it doesn't make sense to go through all that trouble to push more of a drug that has a ticking clock on its patent. Unless this would somehow extend that patent.

Bingo!

 

[geoguy78]

They'll probably end up patenting cagrisema with the sema dosage being significantly higher than what is currently the norm, based on studies like this. I can't imagine jacking up just plain old sema doses given how it already wrecks so many people with GI side effects. I just don't know what market niche cagrisema is going to fill, I suppose it would compete with tirzepatide, especially for the people that just don't lose weight on tirz. That's a pretty small group of people though.

I feel like the market is going to be flooded soon with glp meds. Is there really going to be a place in the market for sema, tirz, reta, maz, survo, cagrisema, orforglipron, and all the others coming to market? Especially when, for the vast majority of people, tirz is good enough?

 

[Airborne Daddy]

While I am loathe to defend a pharma company .. it doesn't make sense to go through all that trouble to push more of a drug that has a ticking clock on its patent. Unless this would somehow extend that patent.

Everytime they change the dose it gets a new drug name.... excellent point.

 

[ZippityDooDah]

Everytime they change the dose it gets a new drug name.... excellent point.

 

[Airborne Daddy]

They'll probably end up patenting cagrisema with the sema dosage being significantly higher than what is currently the norm, based on studies like this. I can't imagine jacking up just plain old sema doses given how it already wrecks so many people with GI side effects. I just don't know what market niche cagrisema is going to fill, I suppose it would compete with tirzepatide, especially for the people that just don't lose weight on tirz. That's a pretty small group of people though.

I feel like the market is going to be flooded soon with glp meds. Is there really going to be a place in the market for sema, tirz, reta, maz, survo, cagrisema, orforglipron, and all the others coming to market? Especially when, for the vast majority of people, tirz is good enough?

I've said that. In 5 years they'll all be obsolete with one that's 5x better and fixes 5 more things these dont.

 

[BooneDonk]

That’s why Reta wakes up in the morning and pisses excellence! 🤣🤣 Covers all the bases we have found at the moment. This space changes quickly….

 

[JoonyO]

Sema is getting left behind.. they are desperate to catch up

No doubt. They're taking a beating from Tirz and even "unapproved" Reta and desperate to stay relevant. I weaned off Sema ( 90 days ) while switching to Reta. The slowing of digestion has been a godsend for me from sema first and reta now, too. A month of Reta on the 18th. Pleased with the results. Can't speak of any unwanted side-effects. All wine and roses for me. 😉