Has anyone heard of GLP's affecting hematocrit levels?

[Kalius]

I saw a single article on it, but I can't seem to find any other information on it.

 

[IshimaruKenta]

I just got my blood work back and my hemocrit levels aren't really any higher than they were off GLP1s.

 

[Mr. Blonde]

Never heard of glps doing this. More of a testosterone or AAS thing.

 

[Airborne Daddy]

Never heard of glps doing this. More of a testosterone or AAS thing.

Op... are you on trt?

 

[Tabletalk]

After beginning try my levels have been slightly elevated, but immediately after dosing glp1 there tends to be a decrease in my hematocrit levels.

 

[Airborne Daddy]

After beginning try my levels have been slightly elevated, but immediately after dosing glp1 there tends to be a decrease in my hematocrit levels.

So the glps balance the slight raise in hematocrit from test? That's good cuz if you were banging 4 or 500mg test weekly it would be too high to donate blood after 6 or 8 weeks.

 

[Tabletalk]

So the glps balance the slight raise in hematocrit from test? That's good cuz if you were banging 4 or 500mg test weekly it would be too high to donate blood after 6 or 8 weeks.

Went back over my hematocrit results:
3yr. on trt - @>50%
3mo. on glp1 - @45% & 46%
(2 total tests)

 

[BioDad]

I saw a single article on it, but I can't seem to find any other information on it.

Dehydration can elevate hematocrit a bit due to hemoconcentration. If your albumin went up, too, that might have been the cause.

 

[Jfrick11]

I just got my blood work back and my hemocrit levels aren't really any higher than they were off GLP1s.

Glp1s can definitely cause nutritional anemia......
Because they suppress appetite and slow digestion, many people eat much less without getting enough nutrients. This can lead to low iron, B12, or folate, which are needed to make red blood cells. Slower digestion can also reduce nutrient absorption, especially iron. Rapid weight loss may temporarily affect iron metabolism, and drinking more water can mildly dilute hematocrit, making levels look lower.

I stumbled across this podcast a few days ago...maybe useful for you.

View: https://open.spotify.com/episode/3HTmpqb0tuPy4Gn7tYIG55?si=oxPYX-KXR8ipOx0JEYZqYQ

 

[Soccerdude]

I just got blood work done, my hct was just below range at 41% and my rbc was low too, 4.38 x10E6/uL.

Besides that, everything else was normal. I think it's because I don't eat red meat because it's expensive. I stick to fish and chicken for my protein.

 

[keangkong]

I looked at my hematocrit levels going back ten years. They've stayed about the same during that entire period, including the five readings taken since I started tirzepatide on August 5, 2024.

 

[Kalius]

Op... are you on trt?

I am on TRT, not really worried about it one way or another, just curious because I saw an article on a medical situation where they took someone off GLP and their hematocrit went up (which was a good thing in the situation).

 

[Kalius]

Dehydration can elevate hematocrit a bit due to hemoconcentration. If your albumin went up, too, that might have been the cause.

I don't have any issues, was just curious.

 

[Kalius]

After beginning try my levels have been slightly elevated, but immediately after dosing glp1 there tends to be a decrease in my hematocrit levels.

How significant was it? I am not having any hematocrit issues at the moment (taking 120mg test/week), but it would be nice to get off GLPs someday, and if I was close to a high level once I'm there, wanted to know if it was something I should consider.

 

[tncc_rn]

Dehydration can elevate hematocrit a bit due to hemoconcentration. If your albumin went up, too, that might have been the cause.

This is the most likely answer....