Recent content by Derby

More information about the Phase 3 trial results: https://www.medscape.com/viewarticle/phase-3-completed-obesity-pill-orforglipron-advances-2025a1000und TL;DR:

LOL, wasn't that the alligator dude?

It was a joke. ETA: Technically, it's possible from a SQ injection from a highly contaminated source in an immunocompromised person, but nothing to realistically be concerned about.

I've used a vial of Tirzepatide over a 3 month period before. Kept in the fridge, good sterile technique, yada yada yada. Last shot was as effective as the first, and I didn't get necrotizing fasciitis or sepsis, so it's all about your comfort level.

The really problematic part is not that one vial was 80% tirz/ 20% reta, the scary part is that one vial was mixed, but the other vial was exactly as advertised. If you knew you had an 80/20 mix, you could probably make it work for you by adjusting the concentration/dose, but not knowing what...

It is absolutely no big deal, I did it for the better part of a year. Just take 2.5 mg in the morning and 2.5 mg in the evening 3.5 days later. (Ex. Tuesday morning and Friday evening) Realistically though, the half-life of tirzepatide is long enough that if you wanted to take it in the...

No, it's fine. Just add 2 mL to 500mg NAD+, and your 100mg is 0.4mL (40 units). I actually reconstitute with 1ml, so 100mg is 0.2mL (20 units). Works fine.

The results of the ACHIEVE-1 trial are published in the NEJM. Bottom line looks like for weight loss it's not quite as effective as injectable semaglutide or tirzepatide, but certainly enough to make it a viable alternative to people who won't do shots...

I concur with everyone else about just sticking with Tirzepatide. I had my best results when I did 2x/week dosing, i.e. 2 mg Tue AM & Fri PM. I would tinker with dose and timing before adding another variable into the mix.

Yes, but that wasn't what the other poster was referring to.

No. Gynecomastia is excess growth of breast tissue, not fat! Even assuming that these fat dissolvers actually work, they will do nothing to reduce breast tissue.

I know this sounds harsh, but how exactly do you expect anyone here to be able to answer this question? We have no way of knowing. You didn't even give the name of the company initially! So welcome to the forum; it's good you found your way here. Now what you have to do is spend a couple of...

It's the smallest quantity that I feel I can easily and reliably draw up correctly on a standard insulin syringe. The cardinal markings (i.e. 0.1, 0.2, 0.3 ...) are easier to see and read, and there's no need to use a bigger volume.

Yeah, solubility isn't really an issue. I prefer an injection volume of 0.2 mL, so I adjust the concentration of my doses to achieve that. I would bet that even the max dose of Tirzepatide of 15 mg is easily dissolvable in 0.1 mL if you wanted to use that.

That seems to be very idiosyncratic. Some people swear that semaglutide is far superior, but I've also heard many success stories with tirzepatide. Food noise was always a very minor issue for me, but what little I had was resolved with 2mg 2x/week of tirzepatide.