Reta anyone splitting their weekly dosages?

JA$$E

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Just doing research here, wondering if people found any benefit to splitting their weekly dosages. I’ve heard it in lesson some of the side effects however, some people saying there’s no clinical evidence to support that. Interested to hear if anyone has tried both and what their results look like.
 
I think from 1mg thru 3mg. I took the dosage once a week.
Now that I'm @ 4mg. I broke the dosage into a Friday 2mg and a Tuesday 2mg dose.

This is my first week on the split dose. So don't really have any data to share yet. But with the single dose on Friday every week; I would get very hungry and want to binge eat end of day Wednesday and Thursday. So hopefully the split dose help with the food noise a little better.
 
JA$$E said:
Just doing research here, wondering if people found any benefit to splitting their weekly dosages. I’ve heard it in lesson some of the side effects however, some people saying there’s no clinical evidence to support that. Interested to hear if anyone has tried both and what their results look like.
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There are many people split-dosing and getting the exact benefits you described. No, there is no clinical data to support it, however there is plenty of anecdotal data (easily found on this site) to support its positive effect on sides and hunger.
 
JA$$E said:
Just doing research here, wondering if people found any benefit to splitting their weekly dosages. I’ve heard it in lesson some of the side effects however, some people saying there’s no clinical evidence to support that. Interested to hear if anyone has tried both and what their results look like.
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Ever since I started titrating up from my starting dose of 2mg/weekly I have split my dosing to two times weekly. I'm now at 10mg/weekly with two 5mg doses per week.
 
I am splitting twice a week, every 3.5 days - I do it at the same time as my TRT. I do find myself slightly hungrier just before the day I am due my dose. I've always done it this way, so have no other experience to compare it to but I don't see any downsides.
 
I inject Sunday's and Thursday's due to my having gnarly sides the first time I injected. I'm sure my body has since adjusted to the medication but as it has been working for me I don't see a need to pivot back to 1x a week.
 
DragonOfTheSea said:
There are many people split-dosing and getting the exact benefits you described. No, there is no clinical data to support it, however there is plenty of anecdotal data (easily found on this site) to support its positive effect on sides and hunger.
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I know "it's against the rules" but I split.
You're not the boss of me!!
 
I went to 2x/wk after upping my dose from 2mg to 4mg/wk. I felt I was feeling hungrier close to the end of the week. I haven't noticed it at all since the switch.
 
I am trying reta after a good run with tirz. I tried reta for about a month when I first started, but I think I started too high for me (2mg) and found the elevated heart rate uncomfortable.
Now on this second go at it, I am starting low and splitting my dose Tuesday and Friday nights. I don't want a repeat of the last run, so I'm liking the smaller amounts at a time.
 
JA$$E said:
Just doing research here, wondering if people found any benefit to splitting their weekly dosages. I’ve heard it in lesson some of the side effects however, some people saying there’s no clinical evidence to support that. Interested to hear if anyone has tried both and what their results look like.
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I ran 2mg e4d (titrated up of course) for about 4 months.
 
I do every 3.5 days, Tuesday AM and Friday PM - so I do my Reta and TRT at the same time, it's just easier for me.

Plotting Reta dosing protocol of 2ml once every 7 days and 1ml every 3.5 days suggests that a twice-a-week protocol results in more stable levels (refer to the Steroid Plotter web site - I can't seem to post links as they are caught by the spam filter)

Also screenshot below showing Reta levels of 2mg/week (blue) vs 1mg every 3.5 days (purple)

1776280969500.webp
 
I'm not in the split camp yet (probably starting this week)

but I found myself dosing every 6 days

I am eating in a deficit that equates to about 2.5-3lbs of weight loss per week, but on day 5/6 I would suddenly eat closer to the 1lb/week deficit

Yesterday was first dose of 4mg, so I will likely do another 2mg on Friday or Saturday and start splitting.
 
I originally split sema doses since the compound telemed set my dosage up that way initially to counteract the sema side effects. It did lessen the side effects and also made it a little more even and less appetite polarized.

I do not do it with reta BUT i do still take a little sema dose (.5) when I notice my appetite is getting a little ramped up, usually about every 7-10 days. So the sema is serving the same purpose to take the edge off before the next reta dose. But also, I am on maintenance right now, giving my skin a chance to catch up to losses so just looking to stay where I'm at on the scale for now. So for that reason I don't want to up my reta. If I did, I might stop the sema bumps and just split the reta as I much prefer reta.
 
JA$$E said:
Just doing research here, wondering if people found any benefit to splitting their weekly dosages. I’ve heard it in lesson some of the side effects however, some people saying there’s no clinical evidence to support that. Interested to hear if anyone has tried both and what their results look like.
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I split them and few woman friends that were getting nausea on 6 days dosing and started splitting theirs and the nausea went away. Make of that what you will!
 
I have been splitting with Tirz since I started last January. Three shots a week, and since I am looking at starting on Reta at a low dose to stack, I am moving that to two Tirz a week and maybe 1-2 of Reta. Maybe like alternating one or the other every 3 days? What I found with the split tirz is that I didn't have that weird crash a couple days before my next dose, like it stayed steady and I didn't feel that peak and valley wave. I am hoping I have the same experience when I add in the stack.
 
domin8brix said:
I have been splitting with Tirz since I started last January. Three shots a week, and since I am looking at starting on Reta at a low dose to stack, I am moving that to two Tirz a week and maybe 1-2 of Reta. Maybe like alternating one or the other every 3 days? What I found with the split tirz is that I didn't have that weird crash a couple days before my next dose, like it stayed steady and I didn't feel that peak and valley wave. I am hoping I have the same experience when I add in the stack.
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Yup.
 
I split my doses. Currently on about 1.7mg of reta every 4 days. since doing this, it has helped my side effects. I only get mild nausea. I find that my hunger is definitely more consistently muted. I've been on reta since Jan.
 
JA$$E said:
Just doing research here, wondering if people found any benefit to splitting their weekly dosages. I’ve heard it in lesson some of the side effects however, some people saying there’s no clinical evidence to support that. Interested to hear if anyone has tried both and what their results look like.
Click to expand...
I do 1mg/week, splitting into two 0.5mg doses. This is my first peptide, so I wanted to start slow so as not to impact my training. It's been working shockingly well. I've been a powerlifter/endurance hiker for 10 years and am using reta to help with shedding perimenopause weight, and I've gone from 162lb to 148lb in 3.5 weeks (I'm 5'10"). I'm actually considering taking it down to 0.5/week because the appetite suppression is impacting my endurance (though lifting is still going fine - not making any PRs but able to maintain my current numbers).
 
I split. Started at 2mg/week about a year ago on Wednesdays and Saturdays. Worked up to 10mg/week before hitting goal and now titrating back down steadily. Expecting to find my sweet spot somewhere in the middle.
 
I moved to 4mg from 2mg three weeks ago.
So I split by adding a second 2mg. (Sun/Thur).
4mg split has nuked my sleep. I'm out by 10p and up at 3:50a like clockwork.
Skipped Thurs and going to 4mg on Sundays to see If I can get some sleep at the tail end of the dose.
I think reducing the crests and troughs by splitting kept me gakked out all week.
Hoping for better sleep.
 
Nerker said:
I moved to 4mg from 2mg three weeks ago.
So I split by adding a second 2mg. (Sun/Thur).
4mg split has nuked my sleep. I'm out by 10p and up at 3:50a like clockwork.
Skipped Thurs and going to 4mg on Sundays to see If I can get some sleep at the tail end of the dose.
I think reducing the crests and troughs by splitting kept me gakked out all week.
Hoping for better sleep.
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Curious to see if that actually helps you.. I would assume that’s going to be even worse but hey, YMMV. (🤣 literally the first time I’ve used that).
 
Nerker said:
Did I get it backwards?
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Not necessarily, you may get that couple days of “better” sleep at the bottom of your valley, I just wonder if your higher peak may bring even worse sides, but it’s worth trying- everyone responds different.
Personally I would have either backed the dose off to maybe 3mg split, or let the 4mg split ride a little longer.
 
JA$$E said:
Just doing research here, wondering if people found any benefit to splitting their weekly dosages. I’ve heard it in lesson some of the side effects however, some people saying there’s no clinical evidence to support that. Interested to hear if anyone has tried both and what their results look like.
Click to expand...
I split dose and am happy with it. Seems to reduce the peaks and valleys. I would get hungrier towards the once a week shot time and have heartburn a few days after my shot. I don’t have that since splitting.
Weight is melting right off.
 
I don't split, since I've not had any debilitating side effects. 10mg/week.
 
Nerker said:
Yes. So shittier sleep in the peak days, better sleep in trough days. Might be better than shitty sleep every night.
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If your trough days are therapeutically effective, you can have lower peaks by split dosing… you can reduce your overall dosage by elevating the trough to be effective with less average exposure.
 
woundcarping said:
If your trough days are therapeutically effective, you can have lower peaks by split dosing… you can reduce your overall dosage by elevating the trough to be effective with less average exposure.
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Hold up. I think I get this. My trough days are effective. I get that split elevates trough. I can go down to 3mg from 4mg but maybe be therapeutically closer to 4mg by splitting?
 
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