Search results for query: reta transition

I haven't seen or heard about anyone successfully using the saline version of H Bac for Reta, only tirz. I believe a while back someone showed a side by side. of what happened using each. I don't know if the brand will be/has been using saline either. If you're using tirz & its working then...

I'm currently on Tir, considering the transition to R if I plateau when I get closer to my goal weight but honestly I can't plan for what ifs, I might grab the case for H Saline BAC since I need it in the near future and will grab some H singles from a US site "just in case". But my thing is...

In maintenance Reta 3mg 1x per week. This was from my previous post of my transition: I was maxed out on 15mg Tirz when I hit goal, after 1 year, 5/25. I dropped the Tirz to 10mg, the following week, then the week following that I went right to Reta, I believe 1 or 1.5 intially, then to 3mg and...

I’ve been using Reta for about 9 months and have lost about 25 pounds as a result. I was briefly on 15 mg per week, but because of reactive hypoglycemia, I cut back to 10 mg per week. I’ve been on that dose for a few weeks now. Since around February, I’ve barely lost any weight—in fact, my...

FINAL UPDATE. As of Friday May 14, 2006, I ended this Journey being 100.6 lbs. I went from 104.8 lbs since April 16, 2026. to 100.6 lbs on May 14, 2026. That's a total loss of 4.2lbs in 4 weeks. Honestly, I think I would have gotten better results had I used Tirzepatide with Reta. Now...

It's an amazing feat to see such progress in 1 year. Proud of all you have accomplished. I will be making the jump to Reta very soon. Just need to get my first order in. Im about 28lbs down in 6 weeks, but adding Tirz kickstarted major drops for me each week. Looking forward to any updates you...

Welcome. There is so much great information here, you're sure to find your way. I think the first month I read hundreds of threads. Not that I'm trying to discourage you from reta, but since you're only at a year on tirzepatide, I'm wondering if you've thought about titrating above the max...

Greetings all. Really great to be here, I am learning a lot from you all. Had a great 1st year on Tirz. Currently at max dosage and am starting to notice a drop in efficacy. Here to learn about Reta and making the transition. I’ve been using an affordable US compounding company but am ready...

It’s working out fine, although I didn’t level off😂. No adverse sides. I started creatine at the beginning of the month after my last DEXA. I’m looking forward to seeing the scale returning to showing results but hope to be rewarded for the patience on the DEXA scan in the coming weeks.

How did that transition work out for you? I never went above 5mg of Tirz because the appetite suppression is just too extreme. Hell, I probably should have never titrated up from 2.5 to begin with... I'm switching over to Reta in the hopes of helping me stay satiated while but allowing some of...

https://medicine.washu.edu/news/stopping-glp-1-drugs-can-quickly-erase-cardiovascular-benefits/ https://www.pennmedicine.org/news/stopping-and-restarting-glp1s-may-make-it-less-effective https://www.legacycommunityhealth.org/newsblog-glp-1-series-what-happens-when-you-quit/...

When I was researching/learning for my transition from Tirz to Reta, the range I settled on for meaningful GCGR activation was 6-8mg, so I made it a point to get to that point quickly. I got to 8mg in early Feb, ~35lb ago. I'm decidedly not avoidant of higher doses, I'm down 55lb I still have...

My GLP-1 journey started with semaglutide. After a few months it just stopped working, so I transitioned to Tirzepatide. I didn't know better, so I started tirz on the lowest dose and quit sema cold turkey, which made my hunger come back with a vengeance and I put on 15lbs I had lost. I was on...

This is my plan. I've been on Tirz for about a year, 10mg, but I've stalled. I am barely eating. I plan on doing 7.5mg of Tirz and 2mg of Reta to start for a few weeks and see how that works, and then slowly lower Tirz and raise Reta. I also plan on doing tesa/ipa once I get my baseline...

Thanks! I didn't mean to make a particular point. The hinkiness in my data is with a couple numbers changing from the day of report (1/30) vs the comparison report made on 4/30. I corrected the data to the most logically rational results, but I'd like to harass them a bit since I've paid...

I've been taking Tirz for a little over two years now. I've been extremely successful and love it. I currently take around 12mg/week. I'm considering adding Reta and/or Tesa on top (really want to blast some visceral fat, and lose some additional weight). So I guess the question I haven't found...

You are describing postural hypotension, where your blood pressure does not adequately increase to account for changes in position, which causes inadequate brain blood flow, dizzyness, faintness, vision going grey etc. It can definitely cause you to faint, so you do need to be a bit careful - if...

I went from Tirz to Reta, rather cold turkey but used a bump of Tirz twice along the way… no big deal. I used frequent small doses to get through the loading phase of Reta quickly, with the target to get to 6-8mg levels as quickly as sides allowed. I have a theory of transitioning from Reta...

What did I say to make you think I don't think increasing dose increases efficacy? My entire point is that low and slow relative to trials could be burning out the time runway before the dose runway, running into the ubiquitous flatline across weight loss peptides and their varying dosages...

Woundcarping - can I ask how you determined this dosing strategy for your transition? Did you have some kind of pharmacokinetic model you were using or did you do this by how you were feeling? It is potentially going to take me a while to find my effective dose if I start low and increase the...

My weight loss target is specific and purposeful, 1% week/week with .9-1.2% being the acceptable short term guardrails without a specific cause for deviation (like a few weeks in to TRT, gained 3lb overnight, took a few weeks to fall off). I had a brief stint with allodynia, not intrusive...

Wassup Peppers, It's time to change up the rotation. I was on Tirz at 10mg before I started to transition to Reta. Here's what I have been pinning: 1. Reta 8mg/week (I'm on week #2 at this dose) on Monday 2. Tirz 5mg/week (I'm on week #2 at this dose) on Friday I have been having an absolute...

You’re welcome to live your life, but with a BMI around 50, anecdotal observations say small doses aren’t likely to be for you (or me). 24% of people on 12mg Reta lost 35% or more of their starting weight. 35% loss puts you around 260lb. Not to consistently yuck your yum; the probability of...

Also as an update to this post I am on my 2nd full day with Reta. Still not feeling sides or anything effects. I understand that it takes time for the drug to build up so I am patiently waiting to take my next dose. Quite a different experience compared to Wegovy as I started noticing its...

I didn't really know that they were side effects, we've had a very intense transition from winter to spring in the Antelope Valley, with 95+ degree temperatures. Plus I had let the grass go in the back yard, so I had spent 4 days mowing and weed whacking (not full days, just till the batteries...

Hi all. So often, the posts on progress that get made are from those unfortunate cases where a person is pinning like 60 mgs twice a week and still can't break the stall. I would love it if you all would share some success stories or encouraging progress if you can. I am too new to really share...

No strong adverse sides. I did get a bit of allodynia earlier on, some GI issues when I first tried to get 8mg 2x week. I backed down to 7mg for one dose, I plan on taking 8mg again tomorrow. Sleep has been fractured a bit but I'm sustaining decent levels with some effort/discipline. These...

I’d like to know, in this order: 1. What dose of Tirz you had reached. 2. How long the bridge phase from Tirz to Reta lasted, and in detail how you managed the dosing during that transition. 3. Whether, as your current Reta dose seems to suggest, you can confirm that you didn’t experience...

Thank you! Yes I’m on shitton of supplements for my PCOS. And yes, miyo d-chiro is one of the suppliments. I feel pretty fine under 0.5mg of Reta. I think I will up it next week to 1.0mg.

Progress looks great! 0.5mg reta is a great stacking dose, but if you ever transition to reta completely you should probably increase your dose sharply if you want to maintain the appetite suppression and avoid bouncing back. I'm a fella, and this is anecdotal, but I find that myo and d-chiro...

I had a lot of fatigue the first week or two but it got better after that. I think part of that was that I was burning more calories. I was shooting for maintenance but started dropping. The numbers showed that it kicked up my daily calorie burn by about 15%. I know it doesn't do that for...

Yeah, only time I've every had real gastro issues was the transition to reta. I was really glad I was doing every 3 days rather than every day, since I was able to notice something was off before I kept increasing.

Thank you for this. I'll think on it. That's very close to my dosage-switch that I'm looking at (8 of tirz to whatever-works-reasonably-well of reta), so it's helpful to hear that experience. And I've never had a single digestive side effect from tirz, survo, or reta, but gastroparesis has...

Yeah, it only feels counterintuitive until you’re the one actually dealing with it. I don’t want to believe it’s not working, it just feels more like you’re in this transition phase where appetite control hasn’t really settled in yet, and I wouldn’t rush the dose. Giving it at least another...

I did a fast transition to Reta from Tirz over ~5 weeks (went from ~7.5mg/week T to ~6mg/week R). I did actually broke it up much like you did the first few shots, but then started separating out the doses to a full week to get the glucagon effect from dose peak. The only thing I'd warn about...

I keep looking at that--if my last dose of 8.8 was 3-16, and I was at steady state, then the amount still in me today should be 0.66 mg. That's close enough to "gone" that I feel like it's safe at this point to say "ok, this is how I feel on this dose of reta." I'm really glad I never...

One thing I’d consider, right now you’re not just “testing reta,” you’re also feeling the absence of tirz at the same time. That overlap makes it hard to tell what’s actually happening. If it were me, I’d focus less on chasing the “right” reta dose this early and more on getting through a clean...

I'll skip the stuff that I don't think you'd be as receptive to, but I'll point out that in a certain sense, losing the last 20 pounds (while on a GLP) in many ways would be very similar to losing the first 20 pounds (had you never discovered the world of GLPs). There isn't really a universal...

That’s awesome! Congrats, especially on your A1C, that’s a huge improvement. Thanks for sharing your experience 🫶 Really interesting to hear how adding reta helped break the plateau and transition into maintenance.

Long story short, I'm about 15 months on tirzepatide and pinned 18mg this morning. I've lost 107lbs and weighed 228 this morning. I'd really like to get to 205, which would put me just into the "normal" weight category for my height. I started a small stack of sema at the end of November...

I have a single data point. A friend tritrated up to 10mg Tirz and lost almost nothing. She said she never felt any hunger supression. She stopped about 6 months ago. She's now on 2mg Reta and is feeling food sizing control - actually eating half a meal and deciding she's full. Fingers crossed...

I appreciate your comment and perspective. I suppose in this scenario I just quit tirz altogether so I'm not overdoing it? I started at 208 lbs and I'm 179 more, 5'4" so maybe current bmi 32 started around 34 You have given me a lot to think about. I recently watched something with a doctor...

I stack Sema and Tirz but unlike most my main is Sema at the moment. I do a dose of Tirz midweek. It's a budget thing for me plus the Sema has worked well so far. The tirz does some good for me inflammation wise. When I finally get thru the sema I bought in the beginning I'll probably...

There are people on 20 mg of tirz who wouldn't start with 6 mg of reta, let alone 8 mg. Those doses would be week nine on a reta trial. Eight weeks is a long time for glucagon adjustments compared to zero adjustment. And this thread is about (less conservative) transitioning (with...

Very interesting way to go about it! Did you get similar sides with tirz or were those specific to reta?

That was a great, thoughtful answer! I was considering adding NAT or Tesa but decided to do this reta/tirz switcheroo instead first to see how that goes. I think your logic is pretty sound and as I boosted turz 1mg/wk with no sides I think that sounds pretty reasonable. I'll let you know how...

I can say that I did that transition about 9 months ago and did a pretty fast titration. I cold turkeyed the Tirz and ramped Reta. The key for me was that I spaced my initial doses at 3days each which is enough to build up the baseline blood concentration, keep the peaks (and hopefully sides)...

Yeah, 6 mg is too high for starting with reta, regardless of tirz history. Better safe than sorry, especially for the glucagon component of reta. I would not start at any higher than 2 mg for the initial reta dose since you can do twice weekly dosing (or even every other day at microdoses). So...

Week 3 begins! Current weight: 169 (down 3 pounds from last week yay!). Do you know how long it's been since I've seen a "16.." prefix on that scale?!! For a brief time a decade ago, and then back in college days. Hello old friend! It's good to see you again. Blood Pressure: 111/66, pulse...

Day 6 Observations: Appetite - earlier, someone said that on Reta they constantly felt like "they'd just eaten a burrito" and I have to agree. Great appetite suppression very early on! I'm eating, but small quantities (prioritizing fibre and protein) and eating more frequently since I'm...