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  1. TooBigtoFail

    My Cagri Chronicle: ongoing updates on progress with cag starting October 2024

    I started Cagri at 0.13mg only. Still, was nauseous for a few days. 6 weeks later, am at 0.3mg. No side effects. As a note, when I started Tirz 2.5mg with compounding Pharma, I got a month supply of Ondansetron 4mg for nausea. Was wondering what did I get myself into. Never used it for Tirz.
  2. TooBigtoFail

    Where to buy Hospira water?

    When I started with a compounding pharma, it did state on the vial: "tirz, benzyl alcohol in sterile water for injection". BUD date was one year away. Read the ingredient list for the Eli Lilly Tirz pen's. It has Benzyl, and is an eye opener on what else is in for ph, saline, etc. A lot of...
  3. TooBigtoFail

    My Cagri Chronicle: ongoing updates on progress with cag starting October 2024

    Yes, 10% of Novo test subjects reported allergic reactions. Ever wonder if allergic to Benzyl, or the mannitol maybe? Its almost the same volume of Mannitol in a 5mg vial or a 30mg vial, so at low doses from 5mg, you get more sugar. Ever tried just injecting Bac alone? Or Saline Bac...
  4. TooBigtoFail

    NEW BAC WATER SUPPLIER NEEDED

    https://form.jotform.com/243402951917155 - member is jailbreak777. Quick shipping.
  5. TooBigtoFail

    Teso is awesome.

    With Tirz, Cagri and Reta, my BP is 99/62 in am, 109/72 pm. Was over 140 before. HR 70-72, was near 80 before peps. I did read about temporary HR increase with Reta, but no increase so far.
  6. TooBigtoFail

    Freezers?

    Walmart - Hisense 5 cu ft Garage Ready Chest Freezer, White, 33.6" Height, 1 Year Warranty, WFC050M6XWD. $165. -8F (-22c) near minimum setting. Will do -20F (-29c) at mid setting. Almost no frost buildup after 4 months. 80watts based on my Kill-a-Watt meter. Quiet. no fan. It use the outer shell...
  7. TooBigtoFail

    My Cagri Chronicle: ongoing updates on progress with cag starting October 2024

    How much are you loosing each week? Am increasing all 3 also, slowly, as my stomach is much much acidic.
  8. TooBigtoFail

    My Cagri Chronicle: ongoing updates on progress with cag starting October 2024

    When I stacked Cagri 0.16mg, to my Tirz 10mg, I was nauseous for first two weeks. Now am ok but zero appetite for past two weeks. When I try to eat, feels like I just ate an hour before. I started stacking Reta 1mg today. All are once a week, with offsets. Targeting to get back to dropping 2...
  9. TooBigtoFail

    Check my math

    For tirz, I use 45-50units because EliLilly (and my compounding pharma) used 50u. There is a science; parenteral preparations. " PRINCIPLES OF RECONSTITUTION • YOU MUST FOLLOW THE MANUFACTURERS DIRECTION FOR RECONSTITUTION. THEY WILL PROVIDE: 1. THE EXPIRATION DATE 2. TYPE OF DILUENT/SOLVENT...
  10. TooBigtoFail

    Are you guys buying BAC every month?

    Yes same. The one with sodium is called isotonic and is very close to blood salt level. Less of a shock to the system. And the mannitol filler in your Tirz, is like sugar, so your injection mix is close to an IV drip. And the sodium version also has benzyl 0.9%. I was buying 3ml bac vial on...
  11. TooBigtoFail

    Supplies for long-term travel with tirzepatide

    Missing the prescription from the doctor..... They know you cannot be prescribed for that much. And maybe some energy bars to eat while you are detained. What is the word I am looking for. Oh yes, paranephilia. "To bring medication into the United States, you must have a valid prescription or...
  12. TooBigtoFail

    How often are you injecting GLOW?

    Did once a day for 5 weeks. I use 31G needles. Had itch day one on Glow 12cc of 0.31mg ghk+0.31mg bpc + 0.31mg tb500. Added bac to 15cc. No other issue but this is a very low dosage. Next batch 20cc injections, and 3rd batch at the end of cycle, 31cc of 1.5mg ghk+0.5mg bcp+0.5mg tb500. Was my...
  13. TooBigtoFail

    Could GLP1 patches be in our future?

    Check Invisicare patent, by Skinvisible. Why not use an insulin pump? How about nicotine or estrogen patches? They work. Why not glp1? I am experimenting with GHK, applied on Tegaderm transdermal patches. There is a patent on such (WO2019167070A1) . GHK-cu mixed with a gel similar to...
  14. TooBigtoFail

    Hospira BAC water availability

    FDA say that the vial could loose its vacuum, and allow bacteria to grow. I don't think predicting when it goes 'bad' is an exact science. More of a legal protection. FDA has extended those dates before. If you filter, you can probably go on for a few extra months. I would throw them out.
  15. TooBigtoFail

    Cagrilintide sides: Anyone have advice?

    Cagri 0.16mg stacking is working. Less appetite and slower digestion. Maybe a tad nauseous when I eat. Cagri or the combo? Is doing its job. Was never nauseous with Triz before. Weight loss has not picked up pace yet.
  16. TooBigtoFail

    Triz from QSC not working

    You should be glad you are not in the hospital. I think jumping around is burning the candle too quickly. From my notes, I stayed 10 weeks at 5mg. Was dropping 1.9 lbs per week average. 0 exercise. The slower you get to 10 or 15mg, the more effective your tirz usage is. Am now at 10mg after 26...
  17. TooBigtoFail

    R10 vs. R20 Puck Size/Weight (Amo)

    Is mainly Mannitol filler, protects the pep during freezing, etc. Without it, you would think its empty. When I buy 20mg of a pep from QSC, I often get 20mg-22mg. They overfill. Should not get 10mg. Jano has no problem separating the mannitol and list the true fill quantity on a COA. If you...
  18. TooBigtoFail

    What are you guys typical weekly dose?

    Congrats and thank you. You are giving me hope that I can reach my 80 lbs target on Tirz (am at 10mg), and just started stacking Cagri. Am down 40 in 6 months.
  19. TooBigtoFail

    Dosing

    An isotonic solution of mannitol (the filler in each vial) is 5%, which seems to be similar to an isotonic 5% solution of glucose. Really need an RN to chime in. Is the amount of mannitol the same in a 10mg vial compared to a 60mg vial? Google AI say is 250mg per vial. Need to weight a full...
  20. TooBigtoFail

    Dosing

    Got to love Wiki, etc. Nursing fundamentals. Read up on water injections, and isotonic. Its about a solution being isotonic, in balance with the tissue where injected, to avoid damage, and help the flow thru the cell membranes. To have a similar balance of solutes as the blood in case it is...
  21. TooBigtoFail

    Dosing

    For me, I start with -how many doses I want to get from a vial? I use 50cc per dose for tirz because Lilly makes it that way. Too little liquid on Glow, GHK, etc and it hurts. So I use about 20-30cc per dose of anything between 0.1 to 2mg. And I do max 50-60cc per pin for me. I suspect there...
  22. TooBigtoFail

    Needle length

    My compounding pharma got me started on EasyTouch 31G 1ml, 5/16 (8mm) long, also called u-100 insulin syringes. I never feel the needle going in, and goes thru all the bac, and pep stoppers without issues. Walmart $20 for 100. I have not used anything shorter. 8mm is not that long when pinning...
  23. TooBigtoFail

    Reta is killing my guts

    Any reason why you stopped Tirz at 3.5mg? I would add back Tirz 3.5mg, every 5 days and slowly increase toward 10mg. Been conservative based on feedback from folks having side effects (which is a key reason folks stop GLP's, according to research). Is your body not liking Reta at all? or is...
  24. TooBigtoFail

    Curious about Chinese vendors incredible shipping times...

    When I use 17track, I can see my order coming by air and entering Cali, city of Industry. ASC from China is faster, than QSC from US warehouse. Go figure.
  25. TooBigtoFail

    Switching hubs from Tz To Reta - Guys - let me know your thoughts?

    Tirz half life is 5 days. Each 5 days, the residual is down by half. Takes 30-35 days. Wait a few days, stack Reta at half the minimum , 1 mg, and climb slowly. I easily cut out a lot of junk because I am not that hungry. 1-2 drinks a week. more fibers. 0 exercise, sit at a desk 12hrs a day, +...
  26. TooBigtoFail

    Reconstituting agent for Cagrilintide

    Great discussions. Google AI results say it may be over the course of 10-20 years of accumulation before plaque forms. Specific conditions. Is there enough material in Cagri 2.5mg weekly, taken for 6 months to be a concern? These are all relatively young GPL medication. In a study, to create...
  27. TooBigtoFail

    Reconstituting agent for Cagrilintide

    I buy StatLab bac 2ml vials (actually has ~3.1-3.5ml) on Amazon. I had one vial half empty (1.6ml) so I added AA 0.6% (from Quality Research Chemical 10 ml on Amazon). After adding 1.4ml of AA, I got pH4.5. No sting, so for next Cagri recon I will do 75% AA to get ~pH4.0. Looks like pure AA...
  28. TooBigtoFail

    Cagrilintide sides: Anyone have advice?

    Tirz is taking away some of my energy. Stomach a bit more acidic, like I had too much coffee. I pop one antacid/calcium tablet about an hour before bedtime. Tirz really slows down my digestion near the end of the day. Does not fell like Cagri has changed anything yet.
  29. TooBigtoFail

    Cagrilintide sides: Anyone have advice?

    Did first Cagri 0.13mg today. Also on Tirz 8mg every 5 days. Will be back.
  30. TooBigtoFail

    Increasing Tirzepatide dosage by smaller increments?

    I suspect that Lilly's protocol is due to the complexity of producing an large inventory of Pen's with many dosage. And Compounding Pharma to follow the same to avoid lawsuits. Plus other financial reasons to benefit them. Based on readings and many folks with success staying on 5mg dosage...
  31. TooBigtoFail

    I tweaked the PH

    Novo Nordisk is testing Cagri with pH4.0-4.5. Got 3 different type of Hydrion test papers, down to pH0.0 tests. Did just like Exploitedworkerbee, mixed roughly 50% bac and 50% AA, to get pH4.5. I added the 300cc bac mix to Cagri 5mg vial. Today, I pinned 7cc for the first time and will ramp up...
  32. TooBigtoFail

    Pep winter is coming - get your orders in NOW!

    You can use https://glp1plotter.com/ to figure out the equivalent dosage to pin under 7 days (11.8mg). For me, it took almost two weeks to feel the change from 7 to 5 days, from the same QSC batch. From day one, my body has never responded in a linear fashion to tirz. And I want to thank...
  33. TooBigtoFail

    Has anybody plotted out serum concentrations of tirz over time based on overlapping dosage at different spacing intervals?

    Excellent link. Tks. So much better than an Excel spreadsheet. Great for not overdosing and for stacking. Now, I wonder how would my rat's body react if I microdose Triz 2.0-2.5mg every day? The residual seems to be pretty constant and the peak about the same as 15mg every 7 days. Is that an...
  34. TooBigtoFail

    Looking for Recommendations: Reliable Suppliers from China

    QSC (Tracy - Qingdao Sigma Chemical Co., Ltd ) if you are patient and accept so so communications. If you wait for a group buy (just a plain sale), you can save 25-40%. Jano reports avail. for most products. I use bank transfer to their US bank. I find ASC ( Angel Shanghai Chem (ASC) as good...
  35. TooBigtoFail

    Tirz5 a but yellow and cloudy

    Was B12 added to your Tirz? Some Compounding pharmacy offer it.
  36. TooBigtoFail

    Tirz5 a but yellow and cloudy

    I get bac from Stat Lab, Amazon. 10X2ml vials filled to the top with 3.5ml. 100% clear all the time. Try Eli Lilly's dilution: for each 2.5mg dose, 25cc, and any dose above 2.5mg to be diluted in 50cc. For 5mg vial, only need 50cc. Based on your comments, I would get a different source of bac...
  37. TooBigtoFail

    How long before pulling fire alarm on QSC?

    Yes. Thanks Jailbreak7. I was expecting to see CAG05, based on Tracy's post for US. That is my lesson, to ask for the SKU code up front. Thanks again.
  38. TooBigtoFail

    How long before pulling fire alarm on QSC?

    Now you are making nervous about all this delayed shipping. Got my order from QSC but the SKU has YSD-55 and 055C, nothing that I can relate to the single product I ordered. Did they mess up? Nothing that match from the SKU's they post. ASC always had something I could match. I hate myself now...
  39. TooBigtoFail

    How long before pulling fire alarm on QSC?

    I ordered on Black Friday and it took twice longer than normal to get my order(US). My USPS orders also were slow. Holidays made it worst?
  40. TooBigtoFail

    Glow Peptide

    Been on my glow mix for 2.5 weeks, each morning. In 30cc, I get 1.2mg ghk, 0.6mg bpc, 0.6mgTb500 (QSC split). When I started first week, at half the dose (0.6ghk,0.3/0.3mg) in 10cc, was a bit painful for a few hours, mild stings on and off (is my first cycle). Dosing in thigh only. Occasional...
  41. TooBigtoFail

    Reconstituting agent for Cagrilintide

    Here is my contribution on the pH: Pramlintide put Novo on the track for Cagrilintide, very stable at pH4. Read this paper "Kinetics of pramlintide degradation in aqueous solution as a function of temperature and pH" https://pmc.ncbi.nlm.nih.gov/articles/PMC2784819/ It provides info...
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