GLP-1 Forum

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  1. hexagonal

    Anyone else receive a Notice of Seizure via certified mail?

    Peptides are on the target list too, but HGH and steroids are higher priority.
  2. hexagonal

    Anyone else receive a Notice of Seizure via certified mail?

    Because in the strictest sense, you are. https://www.fda.gov/drugs/guidance-compliance-regulatory-information/human-drug-imports These almost certainly fail the adulteration and branding requirements for drug importing. It's just that they are almost certainly just going to destroy it and move...
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    Current thoughts on cagri and Alzheimer's?

    Isn't that what they're sold for from the dealership? (this is not political. i've hated teslas ever since i sat in a model s back in 2013 and thought the interior was shittier than car's half their price)
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    If you were a newb... would you start with Tirz or Reta first?

    They extended the reta stage 3 trials past the original end date - presumably to get more data on how much weight is actually lost - but they would have stopped the trials if they had encountered any significant health risks, no? Like we saw with azalaprag?
  5. hexagonal

    What Percentage of Body Weight Have You Lost?

    about 28% since october Tirz until Dec, Reta since then. Started on TRT in October as well. Ipa/Tesa for a bit over two months, two month break, 4IU of HGH now. 5 days of fairly serious lifting very consistently every week, very inconsistent cardio.
  6. hexagonal

    Current thoughts on cagri and Alzheimer's?

    The concern might be around fibrils/oligomers. If so, we've got a few threads on here but nothing definitive. We were waiting to see what the deal was with the pH on the single chamber cagrisema pen, but I don't think we've had any news there in a while.
  7. hexagonal

    All of you have to stop!!!

    Uh. That is explicitly one of the primary things they have been studied for? https://pubmed.ncbi.nlm.nih.gov/21030672/ Collagen deposition is an incredibly important aspect to tendon repair as well https://pubmed.ncbi.nlm.nih.gov/10469335/ Inflammation is another one of the primary causes of...
  8. hexagonal

    All of you have to stop!!!

    Angiogenesis shouldn't cause new tumors, but it is the turbo button for tumor growth. TB-500 has some evidence of metastasization of existing tumors as well. I've not had great luck with my BPC/TB experiments for dealing with tendinopathy. I tried it for dealing with some distal bicep tendon...
  9. hexagonal

    What should I do? shipment lost in the mail from US warehouse (?) - from Shanghai Senria

    You don't want to use FedEx or UPS for anything that can be confiscated. Private companies can just open your packages. Certain classes of mail via USPS can't be opened without a warrant or something like a leak/etc.
  10. hexagonal

    Why does it seem so sketchy! Lol

    You're buying drugs from a drug dealer. There happens to be some sort of legitimate biochem company behind them, somewhere, but the people you're ordering from are drug dealers. Skip the AOD. It doesn't do anything. Mechanism it works on in rodents don't exist in humans. Company discontinued it...
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    Axios: Trump admin won't let Medicare cover anti-obesity drugs

    They only rose to prominence in the Biden administration and the Biden administration started the process to get them covered by Medicare and Medicaid. This is like saying that we shouldn't cover any new thing because it hadn't been covered before. It's not a logical argument and that has...
  12. hexagonal

    If you were a newb... would you start with Tirz or Reta first?

    Most people won't have it jump that high, thankfully. Some people do, though, so I'd recommend starting low and slow and increasing gradually. My RHR is on the high side in general, sits in the 90s with everything I'm taking.
  13. hexagonal

    Ipamorelin/sermorelin or IPA and CJC 1297?

    Even HGH at higher doses than you can get to equivalencies with the secretagogues with will, by itself, do very little to preserve muscle. It's very synergistic with anabolic steroids in that regard, but on its own, way less so. Adequate protein + some amount of muscle growth stimulus will keep...
  14. hexagonal

    Ipamorelin/sermorelin or IPA and CJC 1297?

    Sure, because it's a reasonable suggestion. You can fuck around with a more complicated setup to try and increase your own natural production, or you can just figure out how you respond and set a specific and consistent dose.
  15. hexagonal

    Ipamorelin/sermorelin or IPA and CJC 1297?

    2IU should get most people to IGF-1 levels matching someone in their 20s. 4IU is teens. There are poor and super responders but 3IU or 4IU is going to be supraphysiological for the age range for most people on here.
  16. hexagonal

    Best pep for building muscle and definition

    And I'm on TRT being managed by people who have specialized in it since before it became popular. That doesn't mean that I'm a good source of information. I do not take an AI on a regular dose (I did try some with Primo for two weeks but it increase my RHR too much for me to worry about it at...
  17. hexagonal

    Tracy incognito on meso?

    200mg will put most people significantly above the physiological range. The exact dosage that will shut down your testosterone production varies but for most you're looking at that at even like 30-50mg/week. It can certainly happen even if the exogenous test isn't enough to get you even out of...
  18. hexagonal

    Tracy incognito on meso?

    You're at the top of the range. Every time you blast you risk permanently lowering your natural production levels and needing to use exogenous test to get back to this baseline. Some people can go through tons of cycles and always bounce back. Some people do one and need to pin for the rest of...
  19. hexagonal

    Best pep for building muscle and definition

    Estrogen is cardioprotective and neuroprotective, as well as being anabolic itself. Plenty of overweight people aromatize at lower rates than skinny people - fat cells will aromatize more as a general rule, but genetic variance on aromatization rates is huge. Many of the most informed doctors...
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    Best pep for building muscle and definition

    There's a lot of potential reasons that you want to train concurrently with them besides the muscle growth side of things, but yeah, you will gain muscle. The problem with doing higher quantities while larger or out of shape would be Automatizing more - more of the testosterone will convert to...
  21. hexagonal

    Best pep for building muscle and definition

    Depends on your goal. Doing a bunch of AAS will add muscle regardless. But most of the people doing AAS are on them because they want to look pretty jacked. That'll take hard work, too. AAS have a twofold impact on your muscle mass - they just add it regardless because they signal your body...
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    To filter or not to filter, that is the question

    Yep. Purity tests are about looking at the state of the peptide. Degraded aggregates, incomplete synthesis, etc. The way the tests work doesn't allow for it to test for purity in the way people tend to think. https://trustpointeanalytics.com/2024/05/28/on-peptide-purity
  23. hexagonal

    WARNING: Beware of SRY – Don’t Get Ripped Off!

    Sure, but the advertised quantity is for the peptide itself. There's a lot more than 10mg of lyophilized powder in a vial of <Peptide> 10mg. Meanwhile, a coke dealer is charging you for the full 3.5g of an eight ball, even if half of it is baking soda.
  24. hexagonal

    Tirz or reta

    7.5 is the official therapeutic dose, though some people feel significant effects even at 2.5. Some don't feel anything until 7.5 or even higher. Reta has it's own host of issues from side effects - none of these are side effect free.
  25. hexagonal

    Shot location...

    BS
  26. hexagonal

    WARNING: Beware of SRY – Don’t Get Ripped Off!

    Considering how little each gram of coke you buy is actually cocaine on average, I think coke dealers get away with a hell of a lot more than you give them credit for. The physical nature of the transactions does tend to preclude people sending money and getting no product at all in return, though.
  27. hexagonal

    Heart Rate increase on Tirz

    Tirz increased my RHR, but Reta increased it more. Still like reta and use it.
  28. hexagonal

    Tracy incognito on meso?

    I'd hold off on the AI until you actually have symptoms, personally. Estrogen is beneficial - neuroprotective, cardioprotective, anabolic - up until it starts causing symptoms. Blood pressure, gyno, being overly emotional, etc. I seem to aromatize more or less depending on a variety of factor...
  29. hexagonal

    Types of sources (domestic, overseas, and everything in between)

    3B would be like PGB and Nexaph as I understand it
  30. hexagonal

    Patients scramble as cheaper obesity drug alternatives disappear

    I'm not gonna hate on anyone for wanting/needing a professional to help them with using medications. But yeah, if that's them, grey market ain't the place to be.
  31. hexagonal

    Best pep for building muscle and definition

    Yeah, the aesthetic effects of winstrol are massive. It's super standard in bodybuilder contest prep cycles.
  32. hexagonal

    Best pep for building muscle and definition

    "This showed quite clearly there was no effect on weight" Read the article. It is conclusive that it does nothing in humans. The receptor it relies on just doesn't work the same. There is no method of action. I didn't ignore the fact that you were breaking PRs - I explicitly discussed them as...
  33. hexagonal

    Best pep for building muscle and definition

    It is neither conjecture or assumptions. AOD: https://www.abc.net.au/science/articles/2013/07/26/3811053.htm If there was anyone that could speak to whether or not AOD did anything, it would be the guy they're quoting - Gary Wittert It is not conjecture or assumption to point out that...
  34. hexagonal

    Best pep for building muscle and definition

    AOD doesn't do anything. Mechanism of action that it works on in rodent studies does not exist in humans. Even the lead researcher that worked for the company that was developing the drug and ran their clinical trials has said this. I also can't imagine a worldview where someone feels safer...
  35. hexagonal

    Dosing for dementia prevention?

    Everything I've seen is working off pretty similar dosing schedules which basically mirror the standard dosing for weight loss.
  36. hexagonal

    Non GLP1s for fat burning

    The guy who lead the trials for AOD for the company developing it says it does nothing. Tesa/Ipa can help induce lipolysis and improve nutrient partitioning but you'll still need to be in a caloric deficit for it to cause you to burn fat.
  37. hexagonal

    Best pep for building muscle and definition

    Not super clean, but not awful. I was careful about spacing out the injections from eating as well. Likely. It will increase your HGH production.
  38. hexagonal

    Stacking with Retatrutide

    SLU-PP-332 is not a peptide and there are zero human trials. Anecdotal reports are mixed, outside of influencer circles. People on meso have reported no effect even after injecting significantly higher quantities than what is sold in the tablet form. Other people report seeing significant...
  39. hexagonal

    Best pep for building muscle and definition

    Yes, while on reta and TRT. I saw 3lb of visceral fat reduction on 300mcg IPA/2mg tesa on a 5/2 10 week schedule. I also saw a significant increase in my insulin levels.
  40. hexagonal

    Injectable l-carnitine

    I keep looking at home brewing it. The dosages used for it to have an effect are so high that it is stupidly expensive from most everywhere - .6-1g/day
  41. hexagonal

    peptide suppliers from India or elsewhere?

    China is definitely a part of the opioid crisis. One of the more popular vendors, SRY, has even been indicted for it. I would assume that all of our favorite drug dealers are dealing all the drugs they can make money off of. That way you won't be disappointed when you find out its true.
  42. hexagonal

    Lipo C looks very weird.

    I'm not familiar with Lipo-C in specific but yeah, some things come out of suspension at a bit below room temp. Depending on the temps outside it could have crashed. If warming it up like Andy mentioned resolves the issue, I'd probably go for it. Some formulations will do better at lower...
  43. hexagonal

    Anyone else started a TRT journey with grey?

    Depends on the location, your body fat deposits in the area, etc. I know a lot of people do delts with a 5/8" needle I just do subq though
  44. hexagonal

    Any heavy lifters out there??

    From what I've heard from listening to IFBB pros talking about their cuts, I don't know that there is any standard approach. Seems to vary a lot from coach to coach, and even more if an individual is self coaching.
  45. hexagonal

    To filter or not to filter, that is the question

    Healing injuries requires energy expenditure. Raises your metabolism!
  46. hexagonal

    Unable to inject meds.

    While I believe the janoshik testing on freezing tirz, this post indicates you should be a bit more careful before you act as an authoritative source. You'll notice there is a key word in your quote - dryers. Part of the lyophilization process involves creating a vacuum and drying out the vial...
  47. hexagonal

    To filter or not to filter, that is the question

    HPLC purity tests tell you the purity of whatever they are testing for, not the composition of what is in the vial. That puck you see is almost entirely excipient, generally mannitol. A purity test tells you absolutely nothing about contaminants of most kinds, be it bacteria, mold, heavy...
  48. hexagonal

    WARNING: Beware of SRY – Don’t Get Ripped Off!

    I don't disagree. I'm just stating why I'm not surprised.
  49. hexagonal

    WARNING: Beware of SRY – Don’t Get Ripped Off!

    It looks like this case was legitimate, but we've seen a whole lot of examples of people sending crypto to the wrong place. Wrong coin, wrong network, etc. I've seen 5 or 6 similar complaints in the past few months and all of them ended up being the fault of the person sending the payment. In...
  50. hexagonal

    Anyone else started a TRT journey with grey?

    Yeah. Quality of care when it comes to this stuff is so low on average. You've got a bunch of docs running on outdated information (We've got mountains of studies with tens of thousands of participants showing no increased risk of cardiovascular issues or prostate cancer, to the point the FDA...
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