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  1. hexagonal

    Reconstituting agent for Cagrilintide

    .22um is 220nm, so individual fibrils would still pass through. My understanding is fibrils do tend to clump so you could potentially filter out any large enough clumps, which is why I would personally filter if I were to decide to use cagri.
  2. hexagonal

    Reconstituting agent for Cagrilintide

    Thanks! My biggest worry in engaging on all of this is people assuming I'm some sort of professional and taking my opinion as anything more than a nerd reading papers and interpreting them to the best of his ability.
  3. hexagonal

    yet another scam from Tracy at QSC!

    I've been following bitcoin since mid '09 when the local IRC channel crank that was always coming up with get rich quick schemes was trying to convince us to sign up on some forum and paypal the members in exchange for BTC. I called him an idiot, and he had the last laugh there, but... A decade...
  4. hexagonal

    Reconstituting agent for Cagrilintide

    No one should be taking anything I say as anything beyond my own layperson interpretation of the paper and patent filing, lol. I'm certainly no expert.
  5. hexagonal

    Reconstituting agent for Cagrilintide

    NN is explicit that fibrils do form in cagrilintide, in both that research paper and in the patent. I have quoted those sections extensively across these threads. In the research paper, yes, they use a test that puts it in relatively extreme conditions vs. what is going to be seen after it is...
  6. hexagonal

    GYC shipping vials with zero peptides detected

    I'm not personally getting any colder on reta or previously tirz than I generally ever did, but a friend of mine reports she gets significantly colder on tirz. She has a warm up thing from https://warmies.com/ that she previously largely used for cramps but she was telling me the other day now...
  7. hexagonal

    GYC shipping vials with zero peptides detected

    Yep. Reta injections move my RHR up around 8 hours post injection.
  8. hexagonal

    Injecting too fast?

    Common reaction with MOTS-C. It might be worth trying to slow it down, but it makes zero difference for me.
  9. hexagonal

    Pep winter is coming - get your orders in NOW!

    PT141 interest up 50000% after @stickfigure's review
  10. hexagonal

    Not losing weight on High Tirz

    100%. There are a million things that influence calories in vs. calories out, but the first law of thermodynamics cannot be broken - energy must be conserved. GLP-1s help with reducing your calories in and some have varying impact on calories out, but you can still overcome either effect with...
  11. hexagonal

    Reconstituting agent for Cagrilintide

    They are testing for fibrils on the manufactured material in it's post-buffered state in both the patent and in the paper quoted. They even assess it over multiple weeks in the patent. This is not just during the manufacturing process, this is in it's post-buffer, post-constitution state. There...
  12. hexagonal

    Increasing Tirzepatide dosage by smaller increments?

    When I was on tirz I stayed at 2.5mg for about 6 weeks, and then bumped up to 5mg for 2. At that point I decided I wanted to swap over to the Reta I ordered, though, and stayed at 5mg for another 2 weeks while letting reta get into my system. For reta I did 2mg for 2 weeks, 3 mg for 2 weeks, 4mg...
  13. hexagonal

    Addiction to incretin mimetics

    On the health insurance side of things, https://glp1forum.com/threads/i-lied-to-my-cardiologist-about-being-on-tirz.2093/#post-32753 and the follow up are from someone who has knowledge in the field and says that the ACA prevents them from denying you coverage in this sort of situation. But...
  14. hexagonal

    QSC reta 15 black Friday

    I'm certainly fine with it.
  15. hexagonal

    Addiction to incretin mimetics

    I'm not trying to justify anything. I'm just saying that marijuana had zero impact on my future actions regarding drugs. The fact that I can and have stopped every substance discussed here cold turkey and with zero cravings for months on end when I get busy with work, have to travel for an...
  16. hexagonal

    yet another scam from Tracy at QSC!

    We have that whole novel of a thread about the issues with QSC and bitcoin, lol. Obviously didn't solve it.
  17. hexagonal

    ASC tirz and sema quality?

    Did you even read your own source? Read the 'Disclosure Requirements' section you quoted. "Patent applications must disclose sufficient information to enable others to make and use the invention without undue experimentation"
  18. hexagonal

    ASC tirz and sema quality?

    The entire purpose of the patent system is for all of the pertinent information to be divulged. That's why they came into existence. The line of reasoning is you provide protection to developers of something novel for a limited period of time in exchange for them sharing the information. Prior...
  19. hexagonal

    This forum needs to go private and invite only

    $ dig +short glp1forum.com 176.123.1.233 $ whois 176.123.1.233 | grep netname netname: AlexHost-NET Appears to be a webhost out of Moldova. So yeah, should be safe.
  20. hexagonal

    This forum needs to go private and invite only

    I might, if it was actually true. As GimmeABreak mentioned, much of the Chinese manufacturing industry runs on the '996' system - 9am to 9pm, 6 days a week. There's been pushes to reduce this, but we're still talking 10 hour days, 5 to 6 days a week. CNY is generally an unpaid break for the...
  21. hexagonal

    This forum needs to go private and invite only

    If the peptide industry in China is like every other Chinese industry I have worked with over the years, CNY is effectively a full and complete stop of everything. Nothing will be manufactured, nothing will be shipped, no one will be taking orders. If you're super lucky someone might respond to...
  22. hexagonal

    Addiction to incretin mimetics

    Except I was quite clear that even if pot simply did not exist, I would have done these other drugs. I was interested in them before I ever got into pot - it was just harder for me to get them at the time. I also drank alcohol and had smoked cigarettes beforehand, both of which are psychoactive...
  23. hexagonal

    TRT and GLPs

    Are you some sort of super responder? 25-50mg exogenous T is going to be incredibly low for most people. Do you get regular bloodwork and know your total/free T? But no, TRT for someone with low testosterone getting them into the normal range will not only not counter TRT, but it will help...
  24. hexagonal

    Addiction to incretin mimetics

    I think you mean illicit. Anyway, the idea that marijuana is some sort of gateway drug has been debated by science for decades and is largely (though not entirely) discredited, and the majority of users of harder drugs used nicotine and alcohol before they used marijuana. There isn't full...
  25. hexagonal

    Legal chat: Are we co-conspirators?

    I'll wait for T Swift's death metal era to give her a spin.
  26. hexagonal

    Allodynia much ?

    r/retatrutide has people complaining about allodynia fairly frequently, unfortunately. I've not experienced it myself.
  27. hexagonal

    We're Bashing SRY this time.

    Directions unclear, asking my local drug dealers for methylated fentanyl
  28. hexagonal

    Addiction to incretin mimetics

    Current evidence suggests that these drugs offer benefits such as being cardio-protective even without weight loss. If this is the case, based on our current understanding of unwanted side-effects, stopping them is a negative health impact, even if at goal weight. Anyway, you mentioned the AAS...
  29. hexagonal

    What do you consider a stall in your weight loss journey?

    Just looking at weight can be deceiving. You can still be losing fat and the scale might not move. Some potential confounding factors: 1) You're building lean body mass. A lot of people start doing resistance training for the first time when going on these GLP-1s, and noob gains are a real...
  30. hexagonal

    Company selling "grey" instead of compound on Reddit. $60 for a vial of 10mg or 3 10mg vials for $140.

    You just use the bathtub water instead of the BAC. The primary additional side-effect is the food noise is replaced with simp noise, and you find your bank account quickly draining in the direction of OnlyFans and Twitch subs.
  31. hexagonal

    We're Bashing SRY this time.

    None of this addresses the fundamental point that I am making: Drug dealers deal drugs. None of these drug dealers care about our health or wellness. If they did, they wouldn't sell half of the stuff they do. If you are expecting any of them to be morally superior to SRY, I believe you are...
  32. hexagonal

    We're Bashing SRY this time.

    Drug dealers deal drugs. This is axiomatically true. If any of these chemical companies felt any sort of moral responsibility towards the safety of the users they would only be selling us compounds with well known safety profiles that have been approved by regulating agencies after going...
  33. hexagonal

    How long before pulling fire alarm on QSC?

    My last QSC shipment the boxes all had numbers except one. the #s on the boxes matched the line item # for the peptide in the quote, going 1-6, with the unlabeled box being the 7th item from the order.
  34. hexagonal

    Company selling "grey" instead of compound on Reddit. $60 for a vial of 10mg or 3 10mg vials for $140.

    503As are regulated by state boards which have varying levels of oversight and frequency in inspection. When I was going on compounded tirz originally I looked at the records for the options my doc would send my prescription to and it all looked fairly bleak as to the level of quality control...
  35. hexagonal

    Tirz 15 to Reta equivalent?

    There's no rules on this forum about having to talk about "research subjects" and rats. You can just say it was your stats.
  36. hexagonal

    What's the Best GLP-1 to purchase that has the least Side effects

    Lots of people have no (or minimal) side effects. I had a little bit of constipation but I resolved it pretty easily by upping my fiber intake and drinking more water. (Both of which I needed to do anyway, really.) Also a bit of a resting heart rate increase, but not a ton. Larger increase on reta.
  37. hexagonal

    QSC is screwing around over a $135 credit!

    To be fair, I believe she reported Paypal to the BBB for closing her account, not the CN vendor. But I almost think she'd have better luck going after the CN vendor based on everything I've seen about getting paypal closures reversed.
  38. hexagonal

    Well, fuck peptide test

    It's alright man, if they fit us, everyone can leave us to our delusions. We're not harming anyone!
  39. hexagonal

    Well, fuck peptide test

    I get them with google street view images of the place I lived 8 years ago claiming to be "recent surveillance photos of me"
  40. hexagonal

    Lavender Sky Health exposed my wife's (life saving & emergency) abortion care

    Look, we're listed as married on Facebook OK, you can see it right here in the app, you tell me what happened right now!
  41. hexagonal

    Well, fuck peptide test

    Makes a lot more sense that it was a typo, lol. I was thinking "damn GimmeABreak is cold AF, saying people should be fired around christmas time"
  42. hexagonal

    Well, fuck peptide test

    Firing people for making mistakes is how you have a constant churn of new people making the same mistakes the old ones did. Humans are wired to make mistakes. If you give an employee the task of copy and pasting names into the BCC field when the CC field is right next to it, there's always a...
  43. hexagonal

    Well, fuck peptide test

    Probably just moving to mailing list software instead of manually putting emails in the CC/BCC list. I'm big on understanding mechanisms but I was honestly surprised to see this happen since basically every mailing list service or self-hosted software wouldn't allow for this to happen to begin...
  44. hexagonal

    Lavender Sky Health exposed my wife's (life saving & emergency) abortion care

    Even if brisket explicitly requested his wife's medical records, it's still nothing they should have revealed unless she explicitly had signed off on him having access. Not sure why people are super concerned about the how - the explicit concern is a controlling spouse trying to get the records...
  45. hexagonal

    Deep Sleep Peptides

    I'm skeptical of most anyone discussing specific peptide stacks, even people like dr. seeds - a lot of this stuff has so little real scientific research that basically everything is anecdotal, super small sample size, etc. so many confounding factors. If it works for you and to the best of your...
  46. hexagonal

    Lavender Sky Health exposed my wife's (life saving & emergency) abortion care

    And LSH is a major provider of compounded GLP1s
  47. hexagonal

    Black Market Weight Loss Drug Bust

    I don't think there's any reason for us to carry water for someone who was not adequately explaining the risks of using unregulated research chemicals while deceiving people into thinking they were getting these drugs from a source that was affiliated with some sort of medical facility or...
  48. hexagonal

    The EOY Naughty List

    Customer bought stuff on promo, paid in crypto (BTC) Promo items sold out in between sending money and it being confirmed Got told the credit was good for future purchases, not told there was a time limit Tried to use the credit later, got told the credit was reduced in value, despite Bitcoin...
  49. hexagonal

    Deep Sleep Peptides

    No, because where the water is matters. You're retaining it in places where it is not available for other systems.
  50. hexagonal

    I lied to my cardiologist about being on Tirz.

    I would be wary of that if I told my doctor about that time I smoked opium, or on a more theoretical basis if I had any sort of actual opioid addiction, but despite the marijuana on my chart, I've never had any issue with getting painkillers or similar when I've actually needed them. It doesn't...
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