GLP-1 Forum

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    FBI's Operation Box Cutter indicts 22 Chinese nationals and companies for fentanyl precursors

    I've only ever been offered free drugs by complete strangers I have no association with at concerts. Almost entirely weed - 99.999999% of the time. Ether once. Well, like 5 times in a row by the same guy. The ether made him forget he had offered. At parties from acquaintances, or acquaintances...
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    [SRY] Shanghai Senria Biotechnology

    They (and SSA) were likely raided by Chinese authorities. https://glp1forum.com/threads/ssa-delay.6127/
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    SSA Delay

    Separate shipping is pretty common - peptides/tabs (ancillaries and aas)/oils (aas) have shipped separately from SSA for as long as I've been aware of them, for example. They're made in different factories/labs.
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    SSA Delay

    I expect that to be the case. My reading of the tea leaves is a lot of this is all related to the trade talks, Trump's visit, etc. Just shut down as much of the export of any sort of scheduled substance as possible, even though it's primarily the fentanyl, etc. that has been the focus. Though...
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    SSA Delay

    My limited pattern recognition skills, based on who is still operating and who seems to have been rolled up, seem to point towards AAS as the common denominator. Vendors that ONLY stocked peptides seem to be OK from what I've seen - are there any that weren't involved in the AAS trade that have...
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    Will we be paying tariffs on research peptides?

    We'll be paying some amount of tariffs, but unlikely it will be anything near the actual value. There's just no incentive to declare a $2k peptide order as being $2k vs. $300 or whatever when they already have to provide false documentation on the contents.
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    Can I Make Bac Water?

    Get sterile water for injection and add an appropriate amount of benzyl alcohol. If you can reconstitute a peptide, this shouldn't be any more difficult.
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    Reta + KLOW? Asking questions, needing answers.

    Fellow lifter! I do not believe there is significant benefit to increasing muscle mass through KLOW outside of helping with injuries. Originally following a lot of the "protocols" out there I had zero benefit from BPC/TB, but moving up to 1mg/day for them I did see help with some tendon...
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    Reta + KLOW? Asking questions, needing answers.

    What are you wanting to get out of the KLOW? The GLP-1s are at least proven to fairly-well-proven-in-ongoing-trials medications. I would not recommend adding random peptides just for the sake of having a larger stack. There are various levels of risk for every additional thing you add to your...
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    anyone have any luck negotiating with SSA?

    People pretty regularly spend thousands with these vendors. I can't imagine average order size is less than $500, and they're not going to do any sort of significant price discount on an average order. They have the MOQ discounts listed for the high # of kits for a reason - people are buying...
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    Why isn’t LLY talking up Reta in the news?

    If they have serious concerns about liver damage they wouldn't be continuing the trials. Lilly wouldn't want to risk it themselves, but even if they were, TRIUMPH and all the other phase 3 trials I can find have independent data monitoring committees. These committees exist to review the data...
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    Peptide Myths Busted: Janoshik Founder Sets the Record Straight

    Vagueposting isn't very effective at dispelling whatever idea you're trying to dispel either. As someone that knows neither of you and isn't in STG, I'm more annoyed by this sort of comment than the possibility of someone going "I tried to teach the telegrammers something and then everybody on...
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    Wierd KLOW no pain?

    I have had zero pain with GLOW or KLOW, or even GHK-Cu by itself. I do not spread the injection around or do anything special I just inject it subcutaneously.
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    Need advice dealing with vendor

    Some vendors ship out of multiple warehouses, too, and the minimum is per warehouse. So if you had both tabs and peptides in the same order, for example, they are potentially from different places.
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    Customs clearance

    I don't really want to be in the position of defending the entangled relationship between the US government and big corporations, but this isn't really a fair or accurate characterization of what has occurred. The infrastructure that is allowing for these seizures to occur at increasing rates...
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    AHK-cu

    I explicitly stated I am hesitant about adding more VEGF increasing compounds in my stack because of tumor growth concerns. You replied with this: You are being quite explicit that there is a "humbling" effect from adding capsaicin to your diet when it comes to cancer. You are directly...
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    AHK-cu

    Ivermectin's medical usage is extremely well studied. It's an excellent anti-parasitic and is widely available for the use cases that science supports it for. It is a product of the pharma industry - we would not have it without Merck. But this isn't a defense of big pharma - it is pointing out...
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    AHK-cu

    There is not a single human study showing the efficacy as capsaicin as a cancer treatment in humans. Your own post explicitly calls this out: The only in vivo studies are in animals. It likely has anti-cancer properties. We have no idea how strong they are, if they matter in the face of...
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    Let's talk GLP1's downfall - MUSCLE LOSS

    Usual dosing is about 3G a day. Some people recommend splitting doses or having it next to your workout, others think it's not particularly important.
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    AHK-cu

    I hope you remain cancer free. But science is driven forward by thorough research where variables are controlled for and sample sizes are large enough for us to determine the effect. Anecdotes by individuals aren't data. Capsaicin does show some anti-cancer properties! In vitro. We don't know...
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    AHK-cu

    I'm a big fan of Ed and have a fridge full of Puckerbutt sauces. I would not trust capsaicin to be a panacea for cancer.
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    Let's talk GLP1's downfall - MUSCLE LOSS

    Unlikely we'll see monoclonal antibody stuff with vendors anytime soon. China can produce them, but the facilities that can have enough legit work for pharma that they're not going to be funneling any to the grey or black market.
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    Help: Allergy reaction

    I've been seeing more and more people talking about discussing all of this stuff with doctors, like any reputable doc is going to say anything more than "if your mystery drugs from china are causing you problems stop fucking taking them" I'm convinced it's all AI slop.
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    WBS Tesamorelin Gelling Problem

    They're saying to mix it with acetic acid and more bac water. Tesa is very pH sensitive.
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    BPC 157 & TB 500

    GH operates across different mechanisms than BPC-157/TB-500. All three combined will provide the biggest benefit for injury recovery. (Please remember that all three are also risk factors for accelerating existing cancer growth if you happen to have a cancerous tumor already, so they are not...
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    Silly question: why do supplier discords keep getting nuked?

    Indirectly, from my understanding. My contact at discord says their primary concern is LEOs of various types - which of course are under pressure from big pharma. They're also largely concerned with the controlled substances portion, since many of these vendors are also selling HGH and anabolics.
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    KLOW research

    Angiogenesis and VEGF are well known factors for increasing tumor growth rates. There is no real debate in the science about this, to the point that anti-VEGF/angiogenesis therapies are a current hotbed of research for cancer treatment. BPC-157 and TB-500 promote angiogenesis and increased VEGF...
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    KLOW research

    I'll note that the BPC-157 and TB-500 in both GLOW and KLOW are risks for cancer. Not necessarily in causing it, but for greatly increasing cancer growth rates via angiogenesis and VEGF. TB-500 also seems likely to increase risk of metastisization of existing cancers based on the TB4 research...
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    RHR and Retatrutide

    Tirz raised my heart rate some, reta raised it a lot. I'd be surprised if tirz increased your RHR but reta did not at therapeutic doses. It impacts the sympathetic nervous system the same way tirz does, and the glucagon receptor activation is an additional mechanism for increased RHR. But 2mg...
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    How much weight have you lost?

    Down more than 80lb on the scale and up a bit more than 20lb of lean body mass per dexa in 10 months Tirz for 3 months then reta since then TRT (enough test to get me into the 700s of total T, 80mg deca for joints) for 9 months 4IU HGH for 6 months Hard lifting 5 days a week Some cardio, bad...
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    Let's talk GLP1's downfall - MUSCLE LOSS

    None of the current myostatin inhibitors work particularly well. Effect size is too small.
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    QSC - Don't call it a comeback

    Pretty much every Chinese vendor also deals in steroids. SRY, SSA, etc. As for bodybuilding, the steroid-enhanced body building world is the one that is significantly more popular. (And I would also mention that I believe that basically every single competitive sport where steroids would be...
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    Big Jump in Weight Loss After Starting Reta – Anyone Else?

    A lot of experts would disagree with you - I won't say there's universal agreement, but there's a wide variety of issues with BMI that many argue are so fundamental that it really is useless...
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    Big Jump in Weight Loss After Starting Reta – Anyone Else?

    Well, I'm here for a reason, though I've moved out of the 'obese' category, and I'm getting closer and closer to that <20% bf category, too. GLP-1s are big in the bodybuilding community for helping with cuts, though, and for bodybuilders it really is a useless metric. The verbiage of the OP...
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    Big Jump in Weight Loss After Starting Reta – Anyone Else?

    BMI is a pretty useless metric, particularly for people who engage in regular strength training. Since the OP is talking about lifting regularly, cutting phases, etc., they probably are more muscular than the average person and as such further skewed. All of this is pretty meaningless without...
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    SLU-PP-332 - This made me chuckle

    Rodent studies did 50mg per kg, which translates to about 4mg per kg for humans. Even 20mg is a massive underdose for most of us compared to the studies, though human equivalent dosing isn't always exact. If SLU does anything in humans and is safe to use in general, I suspect 20mg is far more...
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    are you concerned?

    Produced in different facilities, packaged in different ways. Not something I am concerned about, personally.
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    are you concerned?

    DNP is very yellow and is used in much higher doses. The amount of DNP needed to be of concern in a peptide vial would make it very obvious that something is wrong
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    Thoughts on tesa?

    Prescribed for visceral fat in HIV patients on specific medications - they often have significantly impacted IGF-1 levels and egrifta is used to bring it back into the normal range. https://pubmed.ncbi.nlm.nih.gov/15970280/ Personally, I think anyone with normal IGF-1 levels is increasing a...
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    Thoughts on tesa?

    Not actually trying to be funny there - just noting that the study doesn't account for what we might be doing. And who knows what all that might change! I find it plausible that under the right conditions, say, strong nutrient partitioning effects from AAS usage, increased lipolysis and...
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    Thoughts on tesa?

    I don't know that there's good science here to rely on, so it's largely conjecture by bro scientists on the internet. What we do know is that in the non-chemically assisted population, fasted cardio does not result in greater fat loss than non-fasted cardio, as long as other variables are...
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    Thoughts on tesa?

    Plenty of people freeze HGH - it's the same concerns as with most other peptides, ice crystals, etc., can cause issue from repeated thaw/freeze cycles. If you have thermal mass insulating things, have one of the vaccine freezers, etc., it's fine. I've got no concerns about freezing mine and...
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    Thoughts on tesa?

    We do not have in-vivo mechanistic research on why tesa would work more on VAT than GH and even the proposed reasoning by ChatGPT in the followup post after makes no sense - exogenous HGH would also bind more to VAT if it is a matter of increased receptor density. Plenty of people inject HGH...
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    Thoughts on tesa?

    To the best of my (non-expert) knowledge there is no reason to believe that tesa and HGH actually function any differently in regards to visceral fat. We do not know of any mechanism on which tesa acts on VAT or body fat in general outside of increased GH production.
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    Thoughts on tesa?

    Why do you think GH secretagogues don't carry the same risks as exogenous HGH dosed at levels to give you the same amount of GH/IGF-1/etc.? Because a GH secretagogue increasing your natural production to the same level as you would get from exogenous HGH carries those same risks. A tesa/ipa...
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    Reuters: FDA to screen all imports, exemptions for low-value shipments revoked

    None of this matters for our purposes - our vendors are not declaring our shipments as items under FDA jurisdiction. The FDA won't review them unless CBP passes it along after it's already been seized, but it would already have to have been confiscated by CBP to begin with.
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    Let's talk GLP1's downfall - MUSCLE LOSS

    Monoclonal antibodies are massively more difficult to produce than peptides or steroids. It's not impossible - China produces plenty of monoclonal antibodies in general - but they're a lot more expensive and the production capacity is more limited in general. I wouldn't expect to see these in...
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    If this was you, how would you proceed?

    You don't need to freak out and massively change your diet if there's just one or two weeks of stagnation but fundamentally yes, you need fewer calories in. You might need to adjust your macro ratio if energy is a problem, or potentially look at intentional maintenance periods, carb cycling...
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    If this was you, how would you proceed?

    That's the problem - as much as we want to praise these drugs, they actually aren't magic in the bottle. They help us with the CI by reducing appetite and CO by increased metabolism (with reta). SGLT2 inhibitors help by preventing us from absorbing some glucose and instead pissing it out, so...
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    If this was you, how would you proceed?

    This is a lot of words that say absolutely nothing to dispel the facts of CICO. It basically just says that CO isn't a static number and is impacted by a lot of factors, including medication, hormones, etc. Which, well, yeah, of course. No one here is arguing otherwise. My experience is that...
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