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    About to start Sermorelin, what to expect?

    Whether or not you lose muscle depends on your diet and training more than anything when it comes to losing weight while on GLP-1s. Things like TRT (or TRT+) and GH secretagogues (or HGH) will slow down muscle loss if you don't hit your macros and don't do resistance training, but they won't...
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    What do you tell your Doctor

    If it became medically relevant I'd disclose everything. Otherwise I keep it to "I'm on compounded tirz" when in reality I'm on reta. "I'm on TRT" when I long stopped going to a TRT clinic and started sourcing my own test, etc. I'm not too worried since my doctor is laid back, knows about my...
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    About to start Sermorelin, what to expect?

    Expect minimal results, particularly for muscle gain. Even HGH by itself in the absence of steroids is a pretty minimal effects. It's not nothing, but it's not going to be nearly as transformative as the GLP-1s are for weight or going on TRT after being hypogonadal. IGF-1 is a hot topic in...
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    BPC-157 injection site for achilles injuries?

    PRP seems to be much more effective for tendon stuff than BPC/TB/etc., but also significantly more expensive. I've used BPC/TB for more general tendon overuse injuries and they've been effective - but at higher doses than most "protocols" suggest, and I had very little luck with them at the...
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    Endotoxins!

    Endotoxins won't get caught in a filter from my understanding (though any bacteria that could produce endotoxins will), but they're also just not a concern for peptides based on the testing done.
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    Has anyone hit a goal weight in the 19-25 BMI range after large (75lb+) weight loss?

    Male, mid 30s Starting BMI 39.9 / FFMI 18.9 Lowest post-GLP-1 BMI 25.8 / FFMI 22.5 Roughly 120lb of fat lost and 20lb of lbm gained during that period. I started bulking after that point so I'm not maintaining weight, but I never intended to.
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    Blood Pressure/Hypertension not dropping

    GLP-1s/weight loss don't do anything to my BP. Telmisartan/Cilnidipine do a lot for it.
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    Anyone with experience using DSIP for sleep?

    It's above replacement level for the majority of people. It's still well below what pro bodybuilders, etc., run.
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    Mixed messages - klow/glow and history of cancer

    If you don't have cancer or tumors, we don't have any evidence that the stuff in GLOW/KLOW will cause you to get it. If you do have cancer, it will turbocharge it's growth. This can be the difference between catching something at an early stage or a late stage - which can be a life and death...
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    MIX sterility fail

    Unexpected chemicals would be found in GCMS testing. HPLC purity isn't testing for unexpected chemicals. It's focused on the band that represents what you're testing for, and the things that are just slightly out of range are basically degraded bits of the peptide. You could have a vial that...
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    Why are GLPs/peptides so often sent in for testing by customers?

    Exactly this. There is zero legal recourse for you or surviving family members if shit goes wrong with something sold to you by a Chinese UGL, so the only incentive they have is to protect their reputation... but we see new names in this space pop up all the time and get massive quantities of...
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    Looking for Test and Na Selank. Who still sells it?

    Some vendors here might have test incidentally to having peptides, but this isn't an AAS sourcing board. steroidsouretalk or mesorx would be your best bets for equivalents.
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    Has anyone heard of BLOW?

    One of the small handful of things I totally avoid. It just makes me feel like doing more of it.
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    Question About KLOW 80mg – Is the 5 Days On, 2 Days Off Schedule Evidence-Based or Just Anecdotal?

    Sure. Not claiming that she is claiming to be anything else, either. I think adding an active pharmaceutical ingredient to reduce PIP is kind of insane, particularly when you can just dilute it more for the same effect. Especially when she acknowledges the potential cancer growth concerns with...
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    HGH Purity

    HGH is significantly more difficult to synthesize than most of the other peptides we deal with on here, and is synthesized using a totally different process. It's molecular structure is 3D, folded with disulfate bonds Most of the ones we get from the grey market are made using a purely chemical...
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    Question About KLOW 80mg – Is the 5 Days On, 2 Days Off Schedule Evidence-Based or Just Anecdotal?

    There's no particular reason to believe that Anela has any real understanding of what she is talking about, and plenty that she doesn't. Anyone can put together a peptide blend and talk it up on social media. I wouldn't suggest a 5 day on 2 day off schedule either, but the idea that doing so...
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    Weight loss jabs like Ozempic and Mounjaro 'linked to 170 deaths' - including adults in their 20s

    Looks like the MHRA Yellow Card program is about the same as VARS in the USA when it comes to reporting requirements - literally anyone can make the report. They don't have to be any sort of medical professional at all, much less a coroner/medical examiner/foresenic pathologist/similar. My...
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    Basic strength training plan

    TRT or close-ish to TRT levels. The dose that bodybuilders go down to when not "blasting"/being "on cycle" at higher doses.
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    Basic strength training plan

    1) Sounds good. One thing to keep in mind for time saving is that you generally just need to warm up the muscle once per session - if you're doing multiple lifts hitting the same muscles, there's not as much need to warm up each individual lift, since the muscles are already warm. 2/3) This is...
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    Basic strength training plan

    I mean, I've explicitly raised the topic of female TRT in this thread, so I'm certainly aware. If we're talking ng/dl, quest and labcorp have the top of range for test for adult women at 45/64 respectively, so at 100 you're quite a bit above reference range and I do suspect that extended use...
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    Basic strength training plan

    More sets. Rep ranges are more about optimizing across a few different factors. Basically, your rep range you should be one that lets you accurately gauge how close you to are to local muscular failure, gets you to local muscular failure without overly fatiguing you in other ways or getting you...
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    Basic strength training plan

    You can go to failure safely with free weights as well without a spotter, it just requires proper setup. Dumbbells you basically just have to learn how to drop. Barbells you just need a physical spotter rather than a person. I prefer rack mounted safety straps when I use them since you can...
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    Basic strength training plan

    Mentzer was right in that training close to failure with low volume will still induce hypertrophy, and for some people low volume might work better, but the overwhelming majority of people respond better to higher volume, and the science on this is incredibly clear. There are diminishing...
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    Basic strength training plan

    I do not believe pro sports are clean - particularly since I am aware of how easy it is to get around bloodtests. I fully believe ~100% of pro athletes are on PEDs in the MLB, NFL, etc. For the majority of anabolics, virilization is a significant and very noticeable concern for women. For those...
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    What will gray vendors do to compete with new highly reduced prices for US GLP drugs?

    Meanwhile in my state, places with active complaints and warnings will go 12+ months before they even follow back up to see if things were resolved after the initial warning.
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    What will gray vendors do to compete with new highly reduced prices for US GLP drugs?

    The person you are quoting quite explicitly did call him a shill - he claimed he had a vested interest in us believing in the pharma industry. I was also speaking of a specific vaccine - the science is consistent that the covid vaccines, including the mrna versions, were safe and efficacious...
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    What will gray vendors do to compete with new highly reduced prices for US GLP drugs?

    It's still silly to accuse a longstanding member of being an industry shill, particularly right after he points out that pharma tested as less pure than the Chinese underground stuff. Not exactly the sort of thing an industry shill is going to want to point out. As for the vaccines, I could...
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    GLP-1 Drugs Don't Fix Everything

    I basically only talk about this stuff on the internet and with my friends who I lift with, so I don't think so! Unless you were in my garage gym a couple of hours ago.
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    What will gray vendors do to compete with new highly reduced prices for US GLP drugs?

    YYF is very far from an industry shill lol
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    GLP-1 Drugs Don't Fix Everything

    The good news is that even if you lost a lot of muscle while dieting down, getting it back is significantly easier than gaining it the first time. There's still some debate on all the specific mechanisms around it (Satellite cells being deposited and sticking around being one of the leading...
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    Asking about Janoshick

    Assume sterility is a fail. Testing one vial tells you nothing about how sterile another vial is, and it fails regularly enough that long-term use guarantees that you will receive unsterile vials. Filtering will handle sterility concerns. If it's a question that would be relevant to everyone...
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    Asking about Janoshick

    LPS / Heavy Metals - Jano says he has basically never seen these reach harmful levels Sterility - 3-5% of all peptide vials fail sterility checks (Always filter) Personally, I am confident enough to purchase based on purity tests and assume LPS/Heavy Metals are good and Sterility is bad.
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    KLOW research

    Plenty of people talk KLOW/GLOW for benefits beyond just skin - it's quite popular among bodybuilders. You can't take just GHK-Cu/KPV to replicate all the benefits of KLOW without also adding the BPC/TB, which is my point. Regardless of why they were added by some random person to begin with...
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    ABC

    Jano has said ~5% of peptide vials fail sterility tests. One of the reasons I always filter.
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    Mitochondria Repair

    Minimal to no solid science behind their claims. We just have basically no studies supporting most of what they say this stuff does. We'll see mechanistic studies in animals held up as a reason (but look at how that turned out for AOD), some reported anecdotes, etc., but most of the effects they...
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    Death Related to black market weight loss Jabs in UK

    Family members and friends are notorious for blaming random shit that happened temporally close to the death for what happened even when there is no specific reason to believe it was the case. Is it possible it is related? Sure. Do we have any specific evidence here that it was? Nope. But if...
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    Thoughts/Experience: Freezing preloaded syringes of Reta.

    Jano has tested freezing tirz and it was largely fine. Other peptides have seen significant impact. I don't know if reta has been tested, but without having specific knowledge, I'd personally opt to not freeze it.
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    Should I stack tirz and reta, or just use reta?

    Realistically, we have nothing but anecdotal reports on what happens with stacking. We don't know the long term impact and risks, if any. Other glucagon agonist drugs (NN1177) have failed trials due to safety concerns - it's possible the ratio is important to keeping them safe. I personally am...
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    SSA RT30 batch 728D warning and first independent JEEP test

    Thanks for the testing. There's some discussion over on meso that TB frag might be more desirable for most use cases than the full peptide, with the argument being that the fragment is responsible for the benefits we are after, so mg per mg we get more of the useful stuff with frag than we...
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    Basic strength training plan

    I know someone using iamhrt for it. Think there are some subreddits dedicated to female trt that probably know a lot more than I do. SteroidSourceTalk and MesoRX both have some sources that sell lower concentration injectables for women. Lots more to juggle with this side of things, though -...
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    Basic strength training plan

    No one likes being proved wrong :). And I'm just some asshole on the internet - I might not be right! I will say honestly my intention is not to dump on people or win internet points - I just want to make sure we're all looking at all the best information we can so that we have the best chance...
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    Basic strength training plan

    I think this is actually a really important point. Doing any amount of regular exercise - even if it's just half an hour a week - when you were previously doing none? That's an improvement. It will make you healthier. Waiting on a perfect program and doing nothing is just a recipe for staying...
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    Food noise vs. compulsive/boredom eating

    Tirz made it impossible for me to eat enough food to hit my macros - it 100% would have prevented the behavior described. Reta, if I want to eat, I can eat. It doesn't do a whole lot for my physical hunger, either - but that's not what has gotten to me. I'd eat... just because. Think about...
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    Basic strength training plan

    The good news is, you're probably not missing out on anything, re: Machines! https://pubmed.ncbi.nlm.nih.gov/37582807/ Going to failure is still beneficial in that some studies have looked at how good we are at estimating how close to failure we are, and while the answer is "better than you...
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    Basic strength training plan

    None of us should be interested in podcast appearances and similar for anything more than entertainment value and to potentially point us towards things to learn about - we want actual science. People go on Huberman and say all sorts of nonsense all the time, same thing with Attia, etc. Random...
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    Basic strength training plan

    What biological mechanism do you believe happens with older women that causes them to stop responding to muscle growth stimulus the same way everyone else does at all stages of their life? We don't see other significant hormone changes resulting in different muscle growth stimulus being required...
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    Consideration: There is no "stopping" these meds.

    When access to affordable, hyper-palatable, calorie dense food becomes widespread, people get fat. We see it time and time again as countries reach higher levels of wealth and there is greater access to global markets which has this food in abundance, obesity rates start to climb. There's a...
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    KLOW research

    Which would be... not KLOW, which is what this thread is about. The blend in discussion contains these by definition.
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    Basic strength training plan

    We have good studies comparing men vs. women and they are pretty conclusive that women and men respond the same to training. Men make larger gains in absolute terms, but the relative improvement from baseline to finish is very similar. https://pmc.ncbi.nlm.nih.gov/articles/PMC11869894/...
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    Basic strength training plan

    Basically no professional who isn't already indoctrinated into the SS ecosystem recommends starting strength to anyone anymore - even if you want to focus on compound movements, it's just not a well put together program. Elite high school programs moved on, people training adults moved on, etc...
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