Actual number of doses per vial

[JustSomeGuy050]

I’ve had my RS on Reta for a few months now. One of the things I’ve noticed is that I seem to be getting a difference in the theoretical # of doses per vial (example: 10mg w/ 1.0mL Bac @ 2mg dose should give 5 doses @ 20 units) and the actual doses per vial (3-4 with that same math).
I’ve ran my math through so many reconstitution and dosing calculators to make sure I’m not screwing it up.
I do filter with a 4mm filter.
For the last recon I had 12mg and I filtered it with 1mL bac and purged with 0.5mL to give me 12mg/1.5mL for a 2mg dose @ 25 units.
But my RS is 3 shots in to the vial and it looks like there’s only 1 more dose left.
What could I be screwing up? Or is this normal?

 

[Sasquatch]

Why are you jumping back and forth from milliters to units for the dilution?

 

[CNCCurrency]

I’ve had my RS on Reta for a few months now. One of the things I’ve noticed is that I seem to be getting a difference in the theoretical # of doses per vial (example: 10mg w/ 1.0mL Bac @ 2mg dose should give 5 doses @ 20 units) and the actual doses per vial (3-4 with that same math).
I’ve ran my math through so many reconstitution and dosing calculators to make sure I’m not screwing it up.
I do filter with a 4mm filter.
For the last recon I had 12mg and I filtered it with 1mL bac and purged with 0.5mL to give me 12mg/1.5mL for a 2mg dose @ 25 units.
But my RS is 3 shots in to the vial and it looks like there’s only 1 more dose left.
What could I be screwing up? Or is this normal?

No need for RS on here.

 

[jsc1980]

What type of syringe are you using for recon and injecting? Luer loc syringes can have up to 0.1ml (10iu) dead space. So, you could be losing 20 units (one dose) from dead space. Try removing the needle, drawing in some air and air purging to clear some of that dead space.

 

[bada bing]

Every time you move a solution with a syringe and needle there will be small hold back losses. You'll lose a little more by dividing a vial up into many doses rather than one or two, every syringe pull incurs a loss. That said, it shouldn't be much, a unit or two over a vial with proper technique.

 

[jsc1980]

Every time you move a solution with a syringe and needle there will be small hold back losses. You'll lose a little more by dividing a vial up into many doses rather than one or two, every syringe pull incurs a loss. That said, it shouldn't be much, a unit or two over a vial with proper technique.

True if you use a fixed needle syringe, but luer lock syringes/needles have larger dead space. If you are adding bac to a vial, then removing the reconned pep and filtering into a new vial and are swapping needles multiple times without air purging, you could be losing close to 20 units. Even with an air purge, you'll lose a little but much less.

I use luer loc syringes when I inject my trt and leave an air bubble of 5-10 units in the syringe (let the bubble float to the plunger side before starting to inject) so I clear the majority of that dead space.

 

[CNCCurrency]

True if you use a fixed needle syringe, but luer lock syringes/needles have larger dead space. If you are adding bac to a vial, then removing the reconned pep and filtering into a new vial and are swapping needles multiple times without air purging, you could be losing close to 20 units. Even with an air purge, you'll lose a little but much less.

I use luer loc syringes when I inject my trt and leave an air bubble of 5-10 units in the syringe (let the bubble float to the plunger side before starting to inject) so I clear the majority of that dead space.

I use them and filter, I add a little extra bac to compensate or flush.