Anyone who does not store in the fridge?
- Thread starter Gohengrin
- Start date
Found this off the inter web.. ((Compounded pharma versions — For semaglutide/tirzepatide (like compounded versions of Ozempic/Mounjaro/Zepbound), official labeling often allows up to 21–30 days at room temperature (below ~86°F/30°C) after first use or reconstitution, so people follow that and skip the fridge entirely for the in-use period.))
I hope this helps? Im sure you will get more wisdom from more wiser people.
I hope this helps? Im sure you will get more wisdom from more wiser people.
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cygnus
GLP-1 Apprentice
I went the other direction and got a dedicated mini fridge for peptides with the small section freezer section for longer time horizons.
390120
GLP-1 Apprentice
Did it still work?
Theoretically it will rapidly degrade and lose potency so while you may not experience negative effects it might have done nothing after injecting into your body. I wouldn’t risk it and I would just fridge it anyways
Theoretically it will rapidly degrade and lose potency so while you may not experience negative effects it might have done nothing after injecting into your body. I wouldn’t risk it and I would just fridge it anyways
Also look in to a buzzer/ alarm when your Temp drops. I got one on my deep freezer years ago and if things go bad I get a alarm.. I'm sure they are not that much for peace of mind?
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indolent
GLP-1 Specialist
evidence?
indolent
GLP-1 Specialist
As @DjJoshua pointed out, Big Pharma allows a period of room temp. I'm not sure if that covers multi-dose injectors, which are available in some markets.
IMO the concern isn't so much degradation as contamination. My hunch is that if you use bacteriostatic water and you follow good surface-sanitization practices with alcohol swabs, sterility isn't an issue for a couple of weeks of room temperature, as in fridge-failure or travel days. But also refrigeration is better.
IMO the concern isn't so much degradation as contamination. My hunch is that if you use bacteriostatic water and you follow good surface-sanitization practices with alcohol swabs, sterility isn't an issue for a couple of weeks of room temperature, as in fridge-failure or travel days. But also refrigeration is better.
Very Good point
woundcarping
GLP-1 Specialist
"Rapidly degrade" is relative.
Oxidation is considerably slowed when refrigerated, as is hydrolysis, keeping the peptide stable longer. From what I've read refrigeration can slow the degradation by ~4x compared to room temps (it's a range depending on the compound and the process).
Vials with BAC have more bacterial and fungal activity at room temp compared to refrigerated... BAC buys time. Multi use becomes a potential vector for more contaminate.
I have used non refrigerated (~65* temps) peptides in multi use vials. My personal tolerance for non refrigerated vials is something like 2 weeks assuming typical "room temperature".
Oxidation is considerably slowed when refrigerated, as is hydrolysis, keeping the peptide stable longer. From what I've read refrigeration can slow the degradation by ~4x compared to room temps (it's a range depending on the compound and the process).
Vials with BAC have more bacterial and fungal activity at room temp compared to refrigerated... BAC buys time. Multi use becomes a potential vector for more contaminate.
I have used non refrigerated (~65* temps) peptides in multi use vials. My personal tolerance for non refrigerated vials is something like 2 weeks assuming typical "room temperature".
