Anyone with tesamorelin experience?

According to WebMD, even HGH usually only results in a small amount of fat loss:


When adults with an HGH deficiency resulting from pituitary disease are given HGH replacement, it improves body composition -- increasing bone mass and muscle mass and decreasing fat stores.

But it does not cause weight loss in the obese, says Nicholas Tritos, MD, who co-authored an analysis evaluating the effectiveness of HGH for weight loss in obese people.

"Our results showed small improvements in body composition, a small reduction in body fat and increase in muscle mass, but on balance, weight did not change," he says. "More notable changes are seen when an individual is deficient in growth hormone from true pituitary disease."

Another study found that HGH therapy was linked to a small decrease in fat and increase in lean mass, but no change in body weight. The researchers concluded that HGH is not an effective treatment in obese people, and said more studies were needed.

Further, the American Association of Clinical Endocrinologists has warned that the use of HGH for obese patients is not recommended.
 
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I'm only 3 days into taking tesa/ipa/cjc. Today, I was poking through some of my health tracking numbers and noticed that beginning with the first dose, my HRV (heart rate variability) more than doubled. I've been pretty much stuck at an HRV around 45 since I first started tracking it about 4 years ago. Now it's running 85 to 116. That's an unexpected positive change.

I've also been sleeping better the last 3 nights.
 
I'm only 3 days into taking tesa/ipa/cjc. Today, I was poking through some of my health tracking numbers and noticed that beginning with the first dose, my HRV (heart rate variability) more than doubled. I've been pretty much stuck at an HRV around 45 since I first started tracking it about 4 years ago. Now it's running 85 to 116. That's an unexpected positive change.

I've also been sleeping better the last 3 nights.
I've been on it for a month now and sleep quality has most definitely improved by both my personal opinion and my watch tracking my sleep. Routinely getting a 99 sleep score.
 
I'm only 3 days into taking tesa/ipa/cjc. Today, I was poking through some of my health tracking numbers and noticed that beginning with the first dose, my HRV (heart rate variability) more than doubled. I've been pretty much stuck at an HRV around 45 since I first started tracking it about 4 years ago. Now it's running 85 to 116. That's an unexpected positive change.

I've also been sleeping better the last 3 nights.
How long did you do the protocol, and what were your findings?
 
I'm a week on so far. Starting with 1mg a day before bed for the first 10 days then going to bump it up to 2mg for another 5 days before adding in IPA at 250mcg morning and night. So far I haven't noticed much in the water retention but I'm sure it's coming when I jump to 2mg. I don't really care about the water weight though. After it caps out and I start losing again, dropping it at the end of the cycle will be a little bonus to look forward to. I do get little stinging and some itchiness at the injection site as I go to bed, but it's always gone when I wake up. And my sleep has been improving. I'm really optimistic about this stack and am looking forward to seeing some results.
 
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I would go to 1.5 mg before upping to 2 mg. Haven't tried tesa yet, but a buddy of mine had carpal tunnel quickly after going from 1 mg to 2 mg.
 
I would go to 1.5 mg before upping to 2 mg. Haven't tried tesa yet, but a buddy of mine had carpal tunnel quickly after going from 1 mg to 2 mg.
That's the last thing I need right now. I'm currently treating a bad tennis elbow flair up. Damn thing keeps popping up every few months for the last couple years. I'll definitely titrate up slower. Thanks for the heads up.
 
I'm a week on so far. Starting with 1mg a day before bed for the first 10 days then going to bump it up to 2mg for another 5 days before adding in IPA at 250mcg morning and night. So far I haven't noticed much in the water retention but I'm sure it's coming when I jump to 2mg. I don't really care about the water weight though. After it caps out and I start losing again, dropping it at the end of the cycle will be a little bonus to look forward to. I do get little stinging and some itchiness at the injection site as I go to bed, but it's always gone when I wake up. And my sleep has been improving. I'm really optimistic about this stack and am looking forward to seeing some results.
Thanks for sharing this. I plan on running it in a few weeks. I know everyone responds differently but this was a reassuring read.
 
I'm a week on so far. Starting with 1mg a day before bed for the first 10 days then going to bump it up to 2mg for another 5 days before adding in IPA at 250mcg morning and night. So far I haven't noticed much in the water retention but I'm sure it's coming when I jump to 2mg. I don't really care about the water weight though. After it caps out and I start losing again, dropping it at the end of the cycle will be a little bonus to look forward to. I do get little stinging and some itchiness at the injection site as I go to bed, but it's always gone when I wake up. And my sleep has been improving. I'm really optimistic about this stack and am looking forward to seeing some results.
A few tips I've collected regarding managing water weight:

As with HGH, the water retention may be managed by 5 days on, 2 days off, along with staying hydrated and taking more taurine, potassium, and magnesium (to reduce the sodium-based water pressure pushing on the nerves).

"Take 5g of taurine a day when using GH, to prevent/lessen [carpal tunnel syndrome]."

 
Not to change the subject but I wonder how Kisspeptin would compare to the GHRH/GHRPs. It doesn’t mess with HGH yet raises testosterone through LH and FSH stimulation. Might Kisspeptin do much of the same without the tumor promoting fears that excessive HGH and GHRHs bring?
 
Not to change the subject but I wonder how Kisspeptin would compare to the GHRH/GHRPs. It doesn’t mess with HGH yet raises testosterone through LH and FSH stimulation. Might Kisspeptin do much of the same without the tumor promoting fears that excessive HGH and GHRHs bring?

Kisspeptin-10 reliably raises LH and sometimes FSH, but definitely not enough to raise testosterone. You would have to inject roughly every 2 or 3 hours to hope to see a rise in testosterone levels.
 

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