BAC Water vs NaCl Water vs Benzyl Alcohol vs ??? :)

kpake

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Hi everyone, I'm new here. This is my first post after ~2 weeks of digging in and doing focused research. Still learning, but genuinely trying to get a handle on everything!

I just started my journey with 0.5mg semaglutide through a telehealth provider, but I’m seriously considering switching over to reta. As part of that, I’ve been reading up on the best way to reconstitute and, initially, I assumed standard BAC water would be the way to go. But I recently came across a couple sources suggesting that 0.9% sodium chloride might be better because it can reduce the sting. Then I read something else saying, “as long as it contains benzyl alcohol…” and now I’m just confused. :)

If anyone with more experience has any insight or a go-to method they swear by, I’d really appreciate it. Minimizing any sting would definitely be a plus, haha. Thanks so much in advance!
 
Benzoyl alcohol is what makes BAC water, well, BAC water.

I don't know anything about the sodium chloride so I have no input on that.
 
Benzoyl alcohol is what makes BAC water, well, BAC water.

I don't know anything about the sodium chloride so I have no input on that.
Hey, I appreciate your response. That makes sense. So, from your perspective .... BAC water makes sense/is the way to go?
 
Hi everyone, I'm new here. This is my first post after ~2 weeks of digging in and doing focused research. Still learning, but genuinely trying to get a handle on everything!

I just started my journey with 0.5mg semaglutide through a telehealth provider, but I’m seriously considering switching over to reta. As part of that, I’ve been reading up on the best way to reconstitute and, initially, I assumed standard BAC water would be the way to go. But I recently came across a couple sources suggesting that 0.9% sodium chloride might be better because it can reduce the sting. Then I read something else saying, “as long as it contains benzyl alcohol…” and now I’m just confused. :)

If anyone with more experience has any insight or a go-to method they swear by, I’d really appreciate it. Minimizing any sting would definitely be a plus, haha. Thanks so much in advance!
I tried saline and it stung a little less. However you can get less stinging by simply diluting the reta with more BAC water. And once you reconstitute with saline, then you have to use it as it doesn't last long without turning to bacteria soup. If you have stinging issues try using 3ml bac/10mg reta
 
Hey, I appreciate your response. That makes sense. So, from your perspective .... BAC water makes sense/is the way to go?
It's what the majority of people use, aside from some certain peps that may require other types of waters for various reasons, but I haven't delved into any of those yet. For GLPs BAC is pretty standard.
 
I tried saline and it stung a little less. However you can get less stinging by simply diluting the reta with more BAC water. And once you reconstitute with saline, then you have to use it as it doesn't last long without turning to bacteria soup. If you have stinging issues try using 3ml bac/10mg reta
How long can it be stored after mixing with bac water?
 
If getting Sodium Chloride, make sure it's Hospira BAC Sodium Chloride (green lid) - it contains BA just like regular purple lid bac. Not all peptides are compatible with Sodium Chloride, but it does cause less sting with IM injections for things like Botox. For subq I don't think there is much of a difference, unless the pH of the peptide is way off
 
I recently switched to Hospira Saline Bac with Benzyl (yes, the lime/green cap) as 'research'. I noticed that Novo and Lilly use an isotonic mixture for their glp1, which has Nacl. Why would they waste $$ adding saline? More resilient during transport? As they ship recon, maybe it helps shelf life? So far, no noticeable difference of any kind for glp1, ghk-cu, etc.

I commonly used recon's that were 6-8 weeks old with regular bac. No clouding, no issues, same effect. I just make sure I keep everything sterile clean. The regular disclaimer of 28 days is for multi-use, multi patients. Seen studies that show 90 days is upper limit for bac. Jano reported that we worry too much about degradation. 4% was his worst case. Frigo or room temp made little differences. Its really about bacterial growth.
 

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