Changed from Tirzepatide to Reta...not much effect even at a moderate dose

[GuLPing]

Posting to get some opinions here. Could i have a batch with low potency?

I lost 30 pounds on Tirzepatide and didn't even go to huge dosages. At the end, I was at 6mp/week. The peptide was great for appetite reduction, food noise and even beer consumption (2 pints and I was done).

I changed to Retatrutide. Started at 3mg a week. After a month I've titrated up to 6mg. My weight has basically been stable. I've had more energy so I've been working out but it doesn't seem to have done much. Anyone else gone down this path and have opinions on dosages when coming from Tirzepatide? |

I'm kind of wondering if the peptide I got hah an issue. The vendor (who I won't be mentioning) was very responsive and they're well regarded so I'm guessing that's not it.

Any opinions?

 

[lhenderdon]

After a year I was at the max 12.5 mgs of tirz and stalled after loosing 83lbs.
I switched to Reta at 5mgs and actually gained 2lbs after 3 weeks and had
zero appetite suppression. I titrated to 7 mgs and had minimal suppression.
I have since added .5mgs cagri and the suppression was back lost the 2 lbs
that 1st week. Personally I have mixed feelings about Reta it seems the weight
is going down but slowly at .5 to 1lb on a good week.

 

[ZippityDooDah]

Why did you change?

I was on tirz for just over 2 years, at the full 15mg for all but the first ~7 months before I stopped at the end of 2024 due to an 2+ month stall.

I took about 3 months off and started reta this past April. I rapidly escalated my dose since it wasn't doing anything for me, and my 4th dose I tried 12mg and finally found the magic again. I knew the product I had was good (actually averaged a little over 13mg/vial in testing), so I just had to find the point where my body would actually respond.

Bottom line, keep going up until something happens.