Crohn's and Tirz
- Thread starter Nikki nik
- Start date
I don't have Crohn's but know several people who have colitis, including a friend who was on sema and had to do a few months on prednisone to get a flareup under control. Their doctor told them to stop taking sema for the duration of the flareup because there could be an interaction between the two drugs, and that sema may be ineffective while on it. I imagine, without even going into what happens with blood sugar, any weight loss would be masked by the amount of water retention people have on pred.
(and before anyone asks why I'm discussing these things with friends lol, they know i'm on a glp1, and they also know my mom and partner (and tbh my dog too) have colitis and sometimes have to go on pred so i know a bit about it)
(and before anyone asks why I'm discussing these things with friends lol, they know i'm on a glp1, and they also know my mom and partner (and tbh my dog too) have colitis and sometimes have to go on pred so i know a bit about it)
DwightTheDelight
Member
My wife has ulcerative colitis and tirz has helped her tremendously. She used to run to the bathroom 10+ times a day, but tirz has slowed all of that down - less bathroom trips and less urgency while also dropping from 220lbs to 160. It's been amazing for her.
i have a really close friend who has UC and i've been confiding in her about my tirz journey along with the jump to gray. she's curious about it and i think would like to try but is concerned that it would do the opposite of help and actually make her UC flare ups even worse.
what convinced your wife to eventually make the plunge if you don't mind me asking? i want to help her gently to make the plunge with me, at least in the beginning to see if it's worthwhile. i haven't been able to find any "normie proof" data online to send her way to help convince her.
DwightTheDelight
Member
Completely understandable and I'd be lying if I said we weren't nervous as well, but figured if it made things worse, she could just stop. She was ready and willing to do just that at the first sign of trouble, but it's been nothing but positive changes. It's actually crazy how much her situation has improved, because I never see her running to the bathroom anymore. Other than discussing it in these forums, we almost forget she has it now.
My friend was told after having a consultation that sema was safe and she could start being on Crohn's. I was like.....oh nooooo....the gastro side effects are worse.
yeah it seems like for every good experience with regards to crohns/uc and glp1's, there's another story about a bad one. hard to make any strong recommendations to friends when it seems so up in the air.
i do wonder if tirz might be the better option though simply due to the focus on the GLP1 receptor being signifigently less compared to sema.
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