Dermorphin for pain?

[Calm Logic]

I have read a lot on this and even have a couple of vials in the fridge but have never tried it. The dosing is difficult, not enough and you get no pain releif, too much and you risk overdose. The half life means the relief is only a couple of hours and then you have to dose again, but do you dose lower on the second dose? No idea. It also zeps your opioid receptors and will make normal pain relievers (Oxy, hydrodone) less effective. This one is bad news, and I can't see any reason to even try it.

If you're the YOLO type and insist on trying this at least have some narcan in the house and let someone know what you are doing. There are very few peps in the gray world that come with the risk of instant death, this is one of them.

According to some anecdotal reports on Reddit, the pain relief was zero even when they did get some feelz for a minute. Like it's over before it even started.

The one person I found on Discord who said it was a "game changer" was extremely vauge. Nothing about dosing or any other details. So could have been placebo.

And like you are saying, the ones who took a much higher dose (whatever that is) may have had eternal pain relief, and are not here to report back. It would be more deadly without the short half life.

And some people who try it think it's crazy to go to a pain clinic for carefully prescribed opiods that are later dispensed by a real pharmacist. So go figure.

If one is worried about opioid dependency, one can ask a pain doc for buprenorhpine instead or try non-opiods together like meloxicam, gabapentin, duloxetine, and/or LDN.

 

[808otter]

I have read a lot on this and even have a couple of vials in the fridge but have never tried it. The dosing is difficult, not enough and you get no pain releif, too much and you risk overdose. The half life means the relief is only a couple of hours and then you have to dose again, but do you dose lower on the second dose? No idea. It also zeps your opioid receptors and will make normal pain relievers (Oxy, hydrodone) less effective. This one is bad news, and I can't see any reason to even try it.

If you're the YOLO type and insist on trying this at least have some narcan in the house and let someone know what you are doing. There are very few peps in the gray world that come with the risk of instant death, this is one of them.

Yeah spent quite a while with the dosing instructions and wow not one you want to mess up. Looks like it is made from a poisonous frog venom, death by frog don't sound like the way to go but was curious if anyone had tried. Hope you are finding other ways to get some pain relief.

 

[PickleRN]

As a nurse who treats pain patients all day… complete pain relief is sometimes impossible to achieve. However, if you’re searching out other means to control your pain, then it’s not well controlled. You should seek out treatment with a pain management specialist, orthopedic doctor, or neurosurgeon to treat the underlying problem.

 

[Calm Logic]

Exactly. Like for chronic back pain, pain specialists also do shots, nerve ablation, implanted nerve stimulators, etc. Not to mention physical therapy and alternative treatments like inversion tables from Amazon, massage therapy, and chiropractic care.

At-home cold-therapy machines like with knee or shoulder wraps are pretty awesome for any extremity, including the hands, wrists, and feet. They are usually prescribed after surgery, but they can help anytime to reduce pain and inflammation.

For knee arthritis that doesn't get enough relief fom cortisone shots, the interventional radiology procedure GAE is becoming more known as an alternative to knee replacement. There's also nerve ablation. And neurostimulator implants can even be used for knee pain.

For foot pain, even buying new rocker sneakers every three months or so can help. As can orthotics, night splints, cortisone shots, and surgery.

For hand/finger arthritis, paraffin wax can help, as can thermic gloves, meloxicam, Voltaren gel, and cortisone shots (sometimes after an MRI).

I usually live pain-free, but the average age in my part of Arizona is sometimes 65. So almost everyone has been to an orthopedist at least once. I love and hate orthopedists, mostly the latter. I rather see a pain specialist.