Eloralintide

[emptynester]

I was in an Eli Lilly clinical trial for eloralintide. I lost 60 pounds in under a year. It is not a GLP, but a long acting amylin agonist. I kept the weight off for several weeks. When I started putting some back on, I started experimenting with Tirz and Retatrutide. I'm looking to lose a few more before navigating maintenance. I'm looking forward to the results of my study to be published to see how it compares to reta and tirz.

 

[nonyabizznez]

I was in an Eli Lilly clinical trial for eloralintide. I lost 60 pounds in under a year. It is not a GLP, but a long acting amylin agonist. I kept the weight off for several weeks. When I started putting some back on, I started experimenting with Tirz and Retatrutide. I'm looking to lose a few more before navigating maintenance. I'm looking forward to the results of my study to be published to see how it compares to reta and tirz.

F a s c i n a t i n g !!!

It's would be great if you tell us more about the effects of eloralintide! Also how it compares to the GLPs you're trying!

Inquiring minds want to know!

 

[emptynester]

I started at the highest dose without any ramp up. The only side effects I had were constipation and anhedonia. Food noise was gone with the first dose. I had virtually no hunger and felt full very quickly. This is similar to reta and tirz. The big difference I feel is that I slept really well the whole time. I have a hard time sleeping with retatrutide. I also had pretty instant joint pain relief. I don't feel reta or tirz are as helpful with that. The half life is 11 days, so I really never had days that food noise ever really crept back. I think the study will show that weight loss will be slower than with the other two, but I feel it is fast enough. The anti-inflammatory properties alone make me hopeful it will make it to market. I wonder if the anhedonia would have been less if I had been on a lower dose.

 

[nonyabizznez]

Wow! That's a pretty aggressive test! Max dose out of the gate!

 

[m100568]

I would love to swap eloralintide for cagrilintide. If any grey market producers are listening, there is a market for this.

 

[gershon]

hell! 0.6 of cagrilintide zaps my appetite. i'm going to look into this.

as far as grey market, once the patent is published, typically composition of matter patent, the recipe is out!

 

[nonyabizznez]

I started at the highest dose without any ramp up. The only side effects I had were constipation and anhedonia. Food noise was gone with the first dose. I had virtually no hunger and felt full very quickly. This is similar to reta and tirz. The big difference I feel is that I slept really well the whole time. I have a hard time sleeping with retatrutide. I also had pretty instant joint pain relief. I don't feel reta or tirz are as helpful with that. The half life is 11 days, so I really never had days that food noise ever really crept back. I think the study will show that weight loss will be slower than with the other two, but I feel it is fast enough. The anti-inflammatory properties alone make me hopeful it will make it to market. I wonder if the anhedonia would have been less if I had been on a lower dose.

Thanks for responding! Did they tell you what dose you were on? I'm trying to calculate freezer space! 🤣

 

[Dogmandu]

I also had pretty instant joint pain relief. I don't feel reta or tirz are as helpful with that.

If you had rapid joint pain relief even before weight loss, there has to be some potent and independent anti-inflammatory mechanism at play. Did pain return once you stopped? I'm fascinated by what these peptides do besides the obvious.

Also, your sleep thing is encouraging.

 

[emptynester]

9 mg. Some started at 3 and titrated up. Some also may have started at 6. The results should be released fairly soon.

 

[gershon]

hell! 0.6 of cagrilintide zaps my appetite. i'm going to look into this.

as far as grey market, once the patent is published, typically composition of matter patent, the recipe is out!

i have already heard of places offering orforglipron for example....

personally, i want to see a good phase 2 study and get an idea about safety/efficacy before i'd even consider it. we have such data on retatutride and others.

 

[dogmom]

If it helps joints, I could see people being interested in this.

 

[emptynester]

If you had rapid joint pain relief even before weight loss, there has to be some potent and independent anti-inflammatory mechanism at play. Did pain return once you stopped? I'm fascinated by what these peptides do besides the obvious.

Also, your sleep thing is encouraging.

The pain did come back a few weeks later, but I can still be far more active because of the weight loss. My hips and knees feel good and I have been able to run for the first time in 25 years. My sleep is terrible now since I started reta.

 

[emptynester]

i have already heard of places offering orforglipron for example....

personally, i want to see a good phase 2 study and get an idea about safety/efficacy before i'd even consider it. we have such data on retatutride and others.

It should be out very soon. I'm interested to see if my response was the norm.

 

[conzopiriani]

Are you able to access your personal medical data from the clinical trial? Perhaps you signed a release saying you can't have it cause it is part of "blahblahblah" but I would think that this info would be important for any future medical issues that may occur.

 

[emptynester]

I have my usual blood work. I think i can access my dexa scans after the study is published.

 

[pavlovs]

The big difference I feel is that I slept really well the whole time.

For that reason alone, I would take this one. It sounds like it would be a good stacker.
Welcome to the forum!

 

[conzopiriani]

I have my usual blood work. I think i can access my dexa scans after the study is published.

Thanks for the reply. If you would like to share any part of the results I am interested.