Epithalon

vale113

GLP-1 Apprentice
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Hi guys, Does anyone use Epithalon with Reta? I'd like to try it for sleep. Does it help? What dosage should I start with? Many say mcg, others mg.
 
Not on Reta, but my sleep was disturbed from Tirz (as well as being one of those people who constantly wake up)
Hubby and I both do 1mg every 2-3 days. We both are happily sleeping all night. I could not tell you the last time I slept through the night, prior to epithalon.
We are definitely keeping this one around for the long haul.
 
Not on Reta, but my sleep was disturbed from Tirz (as well as being one of those people who constantly wake up)
Hubby and I both do 1mg every 2-3 days. We both are happily sleeping all night. I could not tell you the last time I slept through the night, prior to epithalon.
We are definitely keeping this one around for the long haul.
I had seen that it was cycled every 10 or 20 days based on the dosage, I too, fall asleep immediately, but I wake up many times and I would like to try it
 
I had seen that it was cycled every 10 or 20 days based on the dosage, I too, fall asleep immediately, but I wake up many times and I would like to try it
off topic kinda; my wife wakes several times and has problems falling back asleep, but last night I had her use 250mg Honokiol (Hono-pure Brand) and she told me this morning that although she woke up a few times, she fell right back asleep. Either way, it's a good compound to add.
 
I had seen that it was cycled every 10 or 20 days based on the dosage, I too, fall asleep immediately, but I wake up many times and I would like to try it
We chose not to cycle it. Our goal was sleep. Any other benefits were just a bonus. My understanding is that it does not burn out receptors, like many peps do.
There are many who use it daily, but we found it works great for us every 2 to 3 days.
 
There are a variety of dosages recommended across the different sites and forums, usually 100 mcg-2 mg daily for 10-20 days/month. I’ve been doing 0.5 mg/daily of the NA Epi Amidate for only 8 days now and haven’t noticed a big impact yet. I normally get 0-12 minutes of deep sleep each night and 1 night I showed 54 minutes of deep sleep and got pretty excited. But then it was back to <30 minutes for a couple of nights and now back to zero. I am still optimistic though and will probably run it for 10-20 days per month (depending on what I decide I want to dosage to be). I’ll stick with 0.5 mg this month but may do 1 mg/night next month just to see. I’ve read that anything above about 0.3 mg/day is a waste, particular for the NA Amidate version. All part of the experimentation.
 
There are a variety of dosages recommended across the different sites and forums, usually 100 mcg-2 mg daily for 10-20 days/month. I’ve been doing 0.5 mg/daily of the NA Epi Amidate for only 8 days now and haven’t noticed a big impact yet. I normally get 0-12 minutes of deep sleep each night and 1 night I showed 54 minutes of deep sleep and got pretty excited. But then it was back to <30 minutes for a couple of nights and now back to zero. I am still optimistic though and will probably run it for 10-20 days per month (depending on what I decide I want to dosage to be). I’ll stick with 0.5 mg this month but may do 1 mg/night next month just to see. I’ve read that anything above about 0.3 mg/day is a waste, particular for the NA Amidate version. All part of the experimentation.
I have seen some people taking 5mg even 10
 
Hi guys, Does anyone use Epithalon with Reta? I'd like to try it for sleep. Does it help? What dosage should I start with? Many say mcg, others mg.
I bookmarked a couple of dosing sites. It's best to have a few on hand when trying new peptides, as some are based on legitimate research that they cite and link to (high quality), others use old/outdated research, and some just say "DO THIS" without any explanation and/or justification (low quality). If I find differences/discrepancies between my favorite dosing sites, I then turn to AI and try to figure out WHY there is a discrepancy. If both my sites are giving me duplicate info, I feel more confident in moving forward with the recommended dosing. That's probably the most practical approach the every day person who is not a medical doctor can take for trying to figure these things out 🙂


Here are my top 2 sites and what they say about Epithalon dosing:

Research Dosing: https://researchdosing.com/epithalon/ <-----(EDIT: For some reason, this site is now asking for a reference website. It may no longer be accessible.)

Peptide Dosages: https://peptidedosages.com/single-peptide-dosages/epitalon-epithalon-10-mg-vial-dosage-protocol/


EDIT: Here's another great resource you can use to triangulate/research your dosages for new peptides: https://pep-pedia.org/peptides/epitalon
 
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I bookmarked a couple of dosing sites. It's best to have a few on hand when trying new peptides, as some are based on legitimate research that they cite and link to (high quality), others use old/outdated research, and some just say "DO THIS" without any explanation and/or justification (low quality). If I find differences/discrepancies between my favorite dosing sites, I then turn to AI and try to figure out WHY there is a discrepancy. If both my sites are giving me duplicate info, I feel more confident in moving forward with the recommended dosing. That's probably the most practical approach the every day person who is not a medical doctor can take for trying to figure these things out 🙂


Here are my top 2 sites and what they say about Epithalon dosing:

Research Dosing: https://researchdosing.com/epithalon/

Peptide Dosages: https://peptidedosages.com/single-peptide-dosages/epitalon-epithalon-10-mg-vial-dosage-protocol/


EDIT: Here's another great resource you can use to triangulate/research your dosages for new peptides: https://pep-pedia.org/peptides/epitalon
Thanks a lot, the first one wants to know what site I'm from and therefore it doesn't open
 
Thanks a lot, the first one wants to know what site I'm from and therefore it doesn't open
WOAH, you are right: I copied/pasted the link into a browser I never use and I received the same question. I can access the site just fine through CHROME for some reason. VERY STRANGE> I am adding screenshots of what the site says about Epithalon for you.

1776789860364.webp

1776789898185.webp

1776789916418.webp
 
I have seen some people taking 5mg even 10
That is super high. I read that epitalon is a synthetic version of the naturally occuring epithalamin (which is 10x weaker). The 10 mg doses were studied/administered by the Ukraine Academy Medical Sciences with epithalamin as per below:

- 100 mg total; 10 mg IM q day for 10 days, every year, for 2 years 50 mg total.

- 10 mg IM q every third day, every 6 months, for 3 years.

This is from William M Seed, MD's book "Peptide Protocols"
 
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That is super high. I read that epitalon is a synthetic version of the naturally occuring epithalamin (which is 10x weaker). The 10 mg doses were studied/administered by the Ukraine Academy Medical Sciences with epithalamin as per below:

- 100 mg total; 10 mg IM q day for 10 days, every year, for 2 years 50 mg total.

- 10 mg IM q every third day, every 6 months, for 3 years.

This is from William M Seed, MD's book "Peptide Protocols"
I had seen the same, so I don't understand how to start
 
I had seen the same, so I don't understand how to start
I just received mine and on the same boat as you. I always start super low to see how I will react. Instead of 1 mg a day I might start with 0.5mg and tirtrate to 1mg a day (or 0.25mg and tirtrate to 0.5mg since I am only 110 lbs) and follow the protocol in that book. Keep us posted on how you proceed and what you experience. Anecdotal experiences sometimes seem more realistic than textbook protocols or medical trials (like reta starting at 2mg, for example - way too high for many to start with).
 
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I just received mine amd on the same boat as you. I always start super low to see how I will react. Instead of 1 mg a day I might start with 0.5mg and tirtrate to 1mg a day (or 0.25mg and tirtrate to 0.5mg since I am only 110 lbs) and follow the protocol in that book. Keep us posted on how you proceed and what you experience. Anecdotal experiences sometimes seem more realistic than textbook protocols or medical trials (like reta starting at 2mg, for example - way too high for many to start with).
I still have to order it. I was undecided whether to take it, but I saw that it shouldn't cause any side effects even at high doses. When do you think you'll start? Based on the dosage, I'll decide whether to take a single vial at a significantly higher price than buying the kit.
 
I cycled it for approx. 20 days at 500mcg each night while on Reta, and it was the best sleep of my life. I awoke rested with a clear mind and increased dream/memory retention.

Check out the Russian protocol for dosing; the North American dosing is stupid high and unnecessary, because people are confusing Epitalon dosing for Epithalamin dosing.

TBH, It's my #1 peptide, and I wish it could be cycled more often without the risk of overstimulation/dysregulation of hormonal rhythms.
 
I cycled it for approx. 20 days at 500mcg each night while on Reta, and it was the best sleep of my life. I awoke rested with a clear mind and increased dream/memory retention.

Check out the Russian protocol for dosing; the North American dosing is stupid high and unnecessary, because people are confusing Epitalon dosing for Epithalamin dosing.

TBH, It's my #1 peptide, and I wish it could be cycled more often without the risk of overstimulation/dysregulation of hormonal rhythms.
It's the same one I saw, so I waited to order it, to get opinions from those who have used it, then I could also take a single 10mg vial and do exactly 20 days
 
I still have to order it. I was undecided whether to take it, but I saw that it shouldn't cause any side effects even at high doses. When do you think you'll start? Based on the dosage, I'll decide whether to take a single vial at a significantly higher price than buying the kit.
I planned to start today but not sure if I want to do it tonight or in the a.m. tomorrow. I just received it Friday but didn't get my a$$ in gear to do it this weekend. I took a gamble and ordered the whole kit of 10mg from a US warehouse chinese because it was only $70 and made more finacial sense than a local reseller at $70 per vial. Who knows I might end up with 7 unused vials in my freezer for the rest of my existence. Like someone else said here, "my will's executor can decide what to do with them" 😂
 
I planned to start today but not sure if I want to do it tonight or in the a.m. tomorrow. I just received it Friday but didn't get my a$$ in gear to do it this weekend. I took a gamble and ordered the whole kit of 10mg from a US warehouse chinese because it was only $70 and made more finacial sense than a local reseller at $70 per vial. Who knows I might end up with 7 unused vials in my freezer for the rest of my existence. Like someone else said here, "my will's executor can decide what to do with them" 😂
It would be 33 euros per vial plus water separately, in China I would pay about the same as you but you would have to add 50 usd for shipping, but if I only use 10mg it seems like a waste to have another 9 unused vials, but it would be a great idea to leave it written in my will🤣🤣🤣
 
You don't need massive doses of Epitalon for it to be effective. My first cycle was 1 mg via IN and I just finished my second at 1 mg SQ. I ran for 20 days the first time and 10 days the second time, but I prefer the longer cycle, which I'll do every 4 months. I might go to 2 mg the next cycle, but no further.
 
You don't need massive doses of Epitalon for it to be effective. My first cycle was 1 mg via IN and I just finished my second at 1 mg SQ. I ran for 20 days the first time and 10 days the second time, but I prefer the longer cycle, which I'll do every 4 months. I might go to 2 mg the next cycle, but no further.
So I'll start with the study doses, and I'll see what effect it has on me.
 
Yes, there are a variety of protocols and I think it comes down to experimenting to see what works best for you. Anything showing >2 mg/day I throw out based on the widely cited translation error from the original compound.

As far as whether you do 0.3-0.5 mg/day or 1-2 mg/day, I think that depends on how many times per year you want to run it. If you want to do it 3-4 times per year, then the standard seems to be on the higher side of those ranges I cited. If you want to do it for the first 10 or 20 days per month, then it’s common to do the smaller dosage.

I’ve read all of Chili’s posts and Random’s posts about it and think they’ve given some great details that are worth reading. Lots of great discussions and anecdotal experiences on Peppy’s as well.

The Anela protocol calls for 100-500 mcg/day for 10-20 days each month. That (which I think is close to Random’s protocol if not identical) is what I’ve chosen to do.

Not many protocols differentiate between Epitalon, NA Epitalon, and NA Epitalon Amidate, however. Since NA Epitalon Amidate is more resistant to enzymatic breakdown, I’m choosing to use the smaller dosage.

But, back to the original question of the post, most of the discussions say it helps with sleep tremendously, and that makes sense based on the mechanisms. And I’m excited to experience that as well
 
Yes, there are a variety of protocols and I think it comes down to experimenting to see what works best for you. Anything showing >2 mg/day I throw out based on the widely cited translation error from the original compound.

As far as whether you do 0.3-0.5 mg/day or 1-2 mg/day, I think that depends on how many times per year you want to run it. If you want to do it 3-4 times per year, then the standard seems to be on the higher side of those ranges I cited. If you want to do it for the first 10 or 20 days per month, then it’s common to do the smaller dosage.

I’ve read all of Chili’s posts and Random’s posts about it and think they’ve given some great details that are worth reading. Lots of great discussions and anecdotal experiences on Peppy’s as well.

The Anela protocol calls for 100-500 mcg/day for 10-20 days each month. That (which I think is close to Random’s protocol if not identical) is what I’ve chosen to do.

Not many protocols differentiate between Epitalon, NA Epitalon, and NA Epitalon Amidate, however. Since NA Epitalon Amidate is more resistant to enzymatic breakdown, I’m choosing to use the smaller dosage.

But, back to the original question of the post, most of the discussions say it helps with sleep tremendously, and that makes sense based on the mechanisms. And I’m excited to experience that as well
If I buy the kit I think I'll do 2 or 3 cycles a year at most
 
I've used 1mg for 10 days. Seemed safe enough, but I didn't notice anything. I already sleep hard.
And I may go 10mg a day in the future, but atm, 1mg is fine.
 
Yes, there are a variety of protocols and I think it comes down to experimenting to see what works best for you. Anything showing >2 mg/day I throw out based on the widely cited translation error from the original compound.

As far as whether you do 0.3-0.5 mg/day or 1-2 mg/day, I think that depends on how many times per year you want to run it. If you want to do it 3-4 times per year, then the standard seems to be on the higher side of those ranges I cited. If you want to do it for the first 10 or 20 days per month, then it’s common to do the smaller dosage.

I’ve read all of Chili’s posts and Random’s posts about it and think they’ve given some great details that are worth reading. Lots of great discussions and anecdotal experiences on Peppy’s as well.

The Anela protocol calls for 100-500 mcg/day for 10-20 days each month. That (which I think is close to Random’s protocol if not identical) is what I’ve chosen to do.

Not many protocols differentiate between Epitalon, NA Epitalon, and NA Epitalon Amidate, however. Since NA Epitalon Amidate is more resistant to enzymatic breakdown, I’m choosing to use the smaller dosage.

But, back to the original question of the post, most of the discussions say it helps with sleep tremendously, and that makes sense based on the mechanisms. And I’m excited to experience that as well
I have NA Epitalon on the way (if it ever gets here) and look forward to researching it. I'll probably start at 500 mcg when I do. Being older, with a TBI history, I like the neurological benefits over everything else. Being on Reta also, the sleep pattern changes haven't been as significant, but many people do experience deeper sleep and more REM cycles after a run.
 
I have NA Epitalon on the way (if it ever gets here) and look forward to researching it. I'll probably start at 500 mcg when I do. Being older, with a TBI history, I like the neurological benefits over everything else. Being on Reta also, the sleep pattern changes haven't been as significant, but many people do experience deeper sleep and more REM cycles after a run.
Oh interesting, do you have any information about the TBI-related benefits? Anything published?
 
I am very interested in the difference between NA Epitalon as opposed to regular Epitalon, so if anyone has any experience with that, please do share! It seems logical to assume a lower dose of NA Epitalon may be required to achieve the same result one would at a certain dose of Epitalon, but I haven't been able to find anything on it.
 

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