FDA Registered Manufacturers of Tirz API

[keangkong]

Where does Tracy shop? Is it that other Qingdao place up there??

Ebay.

 

[Lullabytreehugger]

So is tirz from one of these listed companies of better quality?

 

[Vicki]

There's a groupbuy right now for these fda API kits. Yoyo leeching and not giving credit as usual. I bought a few kits myself.
View attachment 4899

Whos the group

But at these prices just give me the bootleg version

 

[GimmeABreak]

So is tirz from one of these listed companies of better quality?

I don't understand how it COULD be better. We get our Tirz tested for fill and purity. Can you get much better purity than 99.5x%? It's not like they are changing the recipe to offer "better" Tirz. I view it as more digital than analog, it is either Tirz, or it isn't.

I swear I saw EL test results for a branded MJ/Zep pen but can't seem to find them now. If I remember correctly it was around the same as gray Tirz and even though the pens come with a 18-24mo BUD the results I saw showed that the pens do degrade significantly during that time period.

 

[Lullabytreehugger]

From what I have gathered to understand in the conversations that I have had with the different manufacturers are the following points,

Raws come in two grades “pharmaceutical grade” and “cosmetic grade”. Also the prices vary accordingly.

This is the actual grade of the raw powder produced. I have no evidence if this is true or not so please dont shoot me down for this.

This one supplier I talked with gave me the price of both grades of raw reta. $650usd for one gram of cosmetic grade raw reta and for the higher pharmaceutical grade the cost will be $850usd per gram.

What this manufacturer told me is that most vendors use the cheaper cosmetic grade raws.

I personally have not tried TCI’s tirz but from what I have read from many forum users is that the tirz from TCI is one of the best out there.

Right now I have a 30mg vial from Ronsen Group tirz. It is crap compared to my original Mounjaro pen. Even though purity was high like 99.21% it just did not feel as good as mounjaro.

What do you guys think about this? Do you think it is true or just conjecture?

 

[exploitedworkerbee]

I don't understand how it COULD be better. We get our Tirz tested for fill and purity. Can you get much better purity than 99.5x%? It's not like they are changing the recipe to offer "better" Tirz. I view it as more digital than analog, it is either Tirz, or it isn't.

I swear I saw EL test results for a branded MJ/Zep pen but can't seem to find them now. If I remember correctly it was around the same as gray Tirz and even though the pens come with a 18-24mo BUD the results I saw showed that the pens do degrade significantly during that time period.

I’m afraid you might not fully appreciate what the purity figure means, there could be dramatic differences. The “purity” is only about the purity of the peptide itself and says nothing about the purity of the contents of the vial as a whole, which contains things other than the peptide. It’s honestly not all that useful a measure, more of a stand-in for “this manufacturer seems to know what they were doing.”

This means that our friendly neighborhood underground labs could be leaving all kinds of crap behind in their manufacturing processes that isn’t showing up in those Jano tests. Presumably the more legit places that are inspected from time to time are less likely to do so.

 

[hexagonal]

I’m afraid you might not fully appreciate what the purity figure means, there could be dramatic differences. The “purity” is only about the purity of the peptide itself and says nothing about the purity of the contents of the vial as a whole, which contains things other than the peptide. It’s honestly not all that useful a measure, more of a stand-in for “this manufacturer seems to know what they were doing.”

This means that our friendly neighborhood underground labs could be leaving all kinds of crap behind in their manufacturing processes that isn’t showing up in those Jano tests. Presumably the more legit places that are inspected from time to time are less likely to do so.

Sure, but the peptide itself should either be it or not. We're likely on the acetate salt versions, but unless we think the buffer in the name brand stuff is significantly different and somehow has an impact on the efficacy vs. ours, it should only be down to the differences from the acetate salt (which I don't believe we have any real science on)

Not that that stops there from being fentanyl or whatever in there along with the peptide and mannitol, of course.

 

[Revo39564]

From what I have gathered to understand in the conversations that I have had with the different manufacturers are the following points,

Raws come in two grades “pharmaceutical grade” and “cosmetic grade”. Also the prices vary accordingly.

This is the actual grade of the raw powder produced. I have no evidence if this is true or not so please dont shoot me down for this.

This one supplier I talked with gave me the price of both grades of raw reta. $650usd for one gram of cosmetic grade raw reta and for the higher pharmaceutical grade the cost will be $850usd per gram.

What this manufacturer told me is that most vendors use the cheaper cosmetic grade raws.

I personally have not tried TCI’s tirz but from what I have read from many forum users is that the tirz from TCI is one of the best out there.

Right now I have a 30mg vial from Ronsen Group tirz. It is crap compared to my original Mounjaro pen. Even though purity was high like 99.21% it just did not feel as good as mounjaro.

What do you guys think about this? Do you think it is true or just conjecture?

From what I have gathered to understand in the conversations that I have had with the different manufacturers are the following points,

Raws come in two grades “pharmaceutical grade” and “cosmetic grade”. Also the prices vary accordingly.

This is the actual grade of the raw powder produced. I have no evidence if this is true or not so please dont shoot me down for this.

This one supplier I talked with gave me the price of both grades of raw reta. $650usd for one gram of cosmetic grade raw reta and for the higher pharmaceutical grade the cost will be $850usd per gram.

What this manufacturer told me is that most vendors use the cheaper cosmetic grade raws.

I personally have not tried TCI’s tirz but from what I have read from many forum users is that the tirz from TCI is one of the best out there.

Right now I have a 30mg vial from Ronsen Group tirz. It is crap compared to my original Mounjaro pen. Even though purity was high like 99.21% it just did not feel as good as mounjaro.

What do you guys think about this? Do you think it is true or just conjecture?

I have heard similar from the middle men….. I really think it was to justify a higher price .…what would be the difference between the two? Maybe the lower grade failed purity testing or was a failed production run? Or maybe it is older…… I could never get a straight answer from the reseller.

 

[GimmeABreak]

I’m afraid you might not fully appreciate what the purity figure means, there could be dramatic differences. The “purity” is only about the purity of the peptide itself and says nothing about the purity of the contents of the vial as a whole, which contains things other than the peptide. It’s honestly not all that useful a measure, more of a stand-in for “this manufacturer seems to know what they were doing.”

This means that our friendly neighborhood underground labs could be leaving all kinds of crap behind in their manufacturing processes that isn’t showing up in those Jano tests. Presumably the more legit places that are inspected from time to time are less likely to do so.

I agree, we don't know what is in 90%+ of the vial and the "filler" could impact how effective the Tirz works. As long as you don't have a adverse reaction to it (like the AMO sting) what we ARE testing matters the most, If you have a good fill an high purity its going to work for most people. I occasionally pin branded Tirz and can't tell the difference. EL's purity standard is actually lower than what we are getting on the gray market. The main difference as far as I can tell is that EL uses a buffer and that gives them longterm storage stability that we don't get once we reconstitute.

 

[scarywood75]

From what I have gathered to understand in the conversations that I have had with the different manufacturers are the following points,

Raws come in two grades “pharmaceutical grade” and “cosmetic grade”. Also the prices vary accordingly.

This is the actual grade of the raw powder produced. I have no evidence if this is true or not so please dont shoot me down for this.

This one supplier I talked with gave me the price of both grades of raw reta. $650usd for one gram of cosmetic grade raw reta and for the higher pharmaceutical grade the cost will be $850usd per gram.

What this manufacturer told me is that most vendors use the cheaper cosmetic grade raws.

I personally have not tried TCI’s tirz but from what I have read from many forum users is that the tirz from TCI is one of the best out there.

Right now I have a 30mg vial from Ronsen Group tirz. It is crap compared to my original Mounjaro pen. Even though purity was high like 99.21% it just did not feel as good as mounjaro.

What do you guys think about this? Do you think it is true or just conjecture?

Very interesting, did they also said what was the difference between the two grades?

 

[BeardedGuy]

so many smart people in these communities. And... maybe 50% agreement on any given issue at any given time. Holy shit this is hard to navigate. But... Let's be honesty, I'm pretty cheap so those I'll be ordering those $190 or less kits.

 

[scarywood75]

so many smart people in these communities. And... maybe 50% agreement on any given issue at any given time. Holy shit this is hard to navigate. But... Let's be honesty, I'm pretty cheap so those I'll be ordering those $190 or less kits.

I get it, money is rare these days

 

[Windingroads06]

So is tirz from one of these listed companies of better quality?

I would think they would be, HOWEVER... I would test with Jano anyway. Trust but verify!

 

[Windingroads06]

Very interesting, did they also said what was the difference between the two grades?

Pharmaceutical vs. Cosmetic-
One I would inject and not blink. One, I'd have to consider it a while as it might contain impurities that could make me seriously ill if taken internally.

Some of the peptides we in the grey market are getting are likely cosmetic grade because the labs are not routinely inspected.

 

[scarywood75]

Pharmaceutical vs. Cosmetic-
One I would inject and not blink. One, I'd have to consider it a while as it might contain impurities that could make me seriously ill if taken internally.

Some of the peptides we in the grey market are getting are likely cosmetic grade because the labs are not routinely inspected.

I am pretty sure the distinction is more complex than just the purity.

It must be a whole different manufacturing process and standards.

I don't think they care about sterile condition, or potential harmful unreached chemicals once ingested for exemple.

I'm interested specifically about the exact differences, I'm gonna ping some to dig into this.

 

[Windingroads06]

I am pretty sure the distinction is more complex than just the purity.

It must be a whole different manufacturing process and standards.

I don't think they care about sterile condition, or potential harmful unreached chemicals once ingested for exemple.

I'm interested specifically about the exact differences.

I would think manufacturing would be similar. Why have a second manufacturing set up to deliberately get a lower quality product and thus less profit?... maybe a bifurcation in the process where the product is combined with other substances to make a different product.

Obviously, there are stricter quality control mechanisms for pharmaceuticals. The differences between GHK-CU pharmaceutical (99.99% purity) and GHK-CU cosmetic grade (>70% purity) is in the fillers.

And, anyway... Technically .... anything less than 99.99 purity is cosmetic grade.

 

[penewbie]

I would think manufacturing would be similar. Why have a second manufacturing set up to deliberately get a lower quality product and thus less profit?... maybe a bifurcation in the process where the product is combined with other substances to make a different product.

Obviously, there are stricter quality control mechanisms for pharmaceuticals. The differences between GHK-CU pharmaceutical (99.99% purity) and GHK-CU cosmetic grade (>70% purity) is in the fillers.

And, anyway... Technically .... anything less than 99.99 purity is cosmetic grade.

Pharma does not reach 99.9 purity, that's impossible (read: prohibitively expensive) for any kind of large scale production.

 

[scarywood75]

I would think manufacturing would be similar. Why have a second manufacturing set up to deliberately get a lower quality product and thus less profit?... maybe a bifurcation in the process where the product is combined with other substances to make a different product.

Obviously, there are stricter quality control mechanisms for pharmaceuticals. The differences between GHK-CU pharmaceutical (99.99% purity) and GHK-CU cosmetic grade (>70% purity) is in the fillers.

And, anyway... Technically .... anything less than 99.99 purity is cosmetic grade.

To reach different markets.

Why do you think we have different car models, etc. It's not just the price, the product itself is often completely built differently.

Fillers are not added at this stage, manufacturers provide the raw (not even lyophilized), excipients are added during lyophilization by finishers.