Filtering

While test peptides are likely not made to full FDA standards in the real compounding pharmacies filtered needles are almost never used. Only practical application is when small all glass (no stopper or cap) ampules are actually broken open, the filter needle prevents risk of glass particles alone. As soon as drawn up the filter needle is discarded and new needle attached. I have zero plans to ever use a filter needle for glp1s. Plus filter needles will not filter out things which could actually cause problems like chemicals and pyrogens.
The raws used a compounding pharmacies are tested for sterility, and they are supposed to also regularly test the sterile area used for recon to ensure it's also sterile.

On top of that, they actually do generally filter as filtering through an appropriate filter is an acceptable way of ensuring the final product is sterile (this is large scale recon, not one fill needle at a time since they don't use needles to fill vials prior to capping). So yes, compound pharmacies absolutely filter.
 

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The raws used a compounding pharmacies are tested for sterility, and they are supposed to also regularly test the sterile area used for recon to ensure it's also sterile.

On top of that, they actually do generally filter as filtering through an appropriate filter is an acceptable way of ensuring the final product is sterile (this is large scale recon, not one fill needle at a time since they don't use needles to fill vials prior to capping). So yes, compound pharmacies absolutely filter.
Sorry you are wrong. I even inspect some of these places as part of my job. Depending on classification, likely 304a or 304b requirements differ. The patient level routine compounding pharmacies are not testing actual compounds, "making sterile" or filtering. They buy sterile, prepare sterile for patient use. If they fall into another category of commercial large scale production and supply people other than end users other requirements and regulations come into play where sterilizing batch product testing, etc regulations apply.
 
I haven't been filtering for UGL AAS like test-c, so I have started to not filter sometimes for peptides, like using a vial of tirz (T10 plus overfill) for relatively single use.

I recently read that C. acnes is so prevalent that it is not uncommon to show up as a false positive when doing pathology samples during surgery. But one can use that to argue either way.

@GLP1Pharmacist, @zpped, and anyone else:

What is your guess that the large compounding pharmacies for GLPs actually filter (like Southend Pharmacy for Brello Health)?
 
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For patient specific compound I doubt they are filtering at all. If they are doing bulk compounding, batching not based on specific patient need they may have to filter or otherwise sterilize. I have surveyed dozens of places that compound and filtering is not occurring unless glass ampules are being broken. They start with sterile products, compound in an aseptic environment such as compounding room with isolater/compounding hood and assign expiration date.
 
If you're willing to say, I'd like to learn a bit more about the compounders. I definitely noticed differences when I switched between them, but couldn't tell why. I assumed it was a difference in material (eg freebase vs acetate etc) rather than in actual amount of peptide. I thought at the time that everything was made in USA/Europe (EL/NN), but I've started doubting that now.

If they aren't using freebase raw, then it seems like they might do some form of reconstitution at scale. That's the only time I could see them filtering. Otherwise, it's easier to just use known sterile equipment, containers, etc in a hood/clean room. What I appreciate about them and pharma is the testing and supply chain integrity that they CAN provide at price and scale.
 
I haven't been filtering for UGL AAS like test-c, so I have started to not filter sometimes for peptides, like using a vial of tirz (T10 plus overfill) for relatively single use.

I recently read that C. acnes is so prevalent that it is not uncommon to show up as a false positive when doing pathology samples during surgery. But one can use that to argue either way.

@GLP1Pharmacist, @zpped, and anyone else:

What is your guess that the large compounding pharmacies for GLPs actually filter (like Southend Pharmacy for Brello Health)?
Would you think c. acnes is a major concern when reconning? Test subject has had issues in the past, unrelated to peptide use.
 
Would you think c. acnes is a major concern when reconning? Test subject has had issues in the past, unrelated to peptide use.
No, it is hard to get clinically infected with C. acnes with subq or even IM injections. It's usually only a concern during shoulder implant surgery. For some reason, it is especially attracted to implants of the shoulder area.

I learned most of this by going with an older relative to their appointment at the infectious disease department of a hospital, after they tested positive for C. acnes after shoulder implant surgery. Since they had some clinical symptoms last year that are associated with infection (stomach issues resulting in major weight loss), they were given three months of amoxicillin after testing positive this year after a second, revision surgery.
 
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No, it is hard to get clinically infected with C. acnes with subq or even IM injections. It's usually only a concern during shoulder implant surgery. For some reason, it is especially attracted to implants of the shoulder area.

I learned most of this by going with an older relative to their appointment at the infectious disease department of a hospital, after they tested positive for C. acnes after shoulder implant surgery. Since they had some clinical symptoms last year that are associated with infection (stomach issues resulting in major weight loss), they were given three months of amoxicillin.
Good to know and yes I am familiar with C. Acnes with RS as well for similar post surgery issues.
 

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