Final Verdict - Split Dose?

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GLP-1 Apprentice
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Im looking for those of you who’s RS has been taking reta for an extended period of time and tried both weekly and split dosing to chime in on efficacy. Feel free to add studies or any data other than personal experience, but im mainly looking for first hand. Did splitting the dose have an effect on your fat loss or not?
 
The area under the curve is the same either way.

Split could increase weight loss potential by allowing higher dosing with lower peaks potentially causing less sides.

Split could decrease the need for a higher dose to sustain appetite suppression through higher troughs at the lower dose.

There’s no practical magic either way. I weeklied for 3 weeks and have split the 18 weeks since. Down 55lb in total, no meaningful issues with sides, life is good.
 
I've split and weekly dosed. The weekly dose is way more stable for me. More consistent weight loss and appetite. This was the opposite of what I'd expected, but split dosing had me dealing with more swings and less effectiveness. This might just be me, but I will not go back to split dosing.
 
for me since a split dose daily no more peak and stable at 4mg and no more side effect
and i can eat my 2000 cal daily but need to watch out for the late night munchies
 
Im looking for those of you who’s RS has been taking reta for an extended period of time and tried both weekly and split dosing to chime in on efficacy. Feel free to add studies or any data other than personal experience, but im mainly looking for first hand. Did splitting the dose have an effect on your fat loss or not?
I just this past week started splitting my reta dose after 4 months. I titrated up to 5mg a few weeks ago from not feeling any side effects at 4 for a while. I got sick for about 10 days so I decided to split my dose on Monday night, then I pinned the rest this morning. I probably won't know more for a few weeks as far as fat loss but I can say I don't feel any side effects as of yet. I will give an update when I know for sure how it's working.
 
I did 1 dose a week for 9 weeks and titrated up to 4mg but I only lasted 2 weeks at that dose. The primary and side effects were killing me. I've been splitting every 3-3.5 days since then and am happy with the results.
 

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