GLP1 maintenance

[Seamus]

Has anyone either lost weight through Retatutide or Tirzapzide at a moderate tonight dose,and is now using a lower dose for maintenance??

If so which dose,how long for and what's the results??

 

[TacoLifter420]

Has anyone either lost weight through Retatutide or Tirzapzide at a moderate tonight dose,and is now using a lower dose for maintenance??

If so which dose,how long for and what's the results??

I lost 70 pounds over 7.5 months on Tirz, never went over 5mg per week and currently use 2 mg every 5 days. At 2mg my weight is slowly going down by half a pound a week or so. I also train really hard and I'm on TRT.

 

[Ragu1]

Has anyone either lost weight through Retatutide or Tirzapzide at a moderate tonight dose,and is now using a lower dose for maintenance??

If so which dose,how long for and what's the results??

I was on 2.5 tirz for about a year lost 50lbs. When I started this journey a couple years back, the mantra/advice was slow and steady. Only need to increase your dose if you stalled. I did go do 5mg a couple of times, but that was only to break a stall..
I have been on maintenance for almost a year.. still on 2.5 but have used survo to help. I work out at least 5 days a week mainly cardio and legs as I have torn rotator cuff with severe arthritis. Looking at reverse shoulder replacement in Jan. My goal now is to maintain or lose a few more pounds because I know I'll be laid up with my recovery.

 

[Seamus]

I lost 70 pounds over 7.5 months on Tirz, never went over 5mg per week and currently use 2 mg every 5 days. At 2mg my weight is slowly going down by half a pound a week or so. I also train really hard and I'm on TRT.

So that dose is enough to prevent over eating then?

 

[AndyPanda]

Has anyone either lost weight through Retatutide or Tirzapzide at a moderate tonight dose,and is now using a lower dose for maintenance??

If so which dose,how long for and what's the results??

On a pharmacokinetic level, if you want to remain on lower doses or micro dose, Tirz is better. You will eventually need to titrate up though.

Retatrutide has a 144 hour half life. That's 6 days. Steady state concentration where the peptide actually works takes 4 to 5 half-lives which is 24-30 days of consistent weekly dosing to build a theraputic platue. The weekly injection is not arbitrary. Micro-dosing Reta sabotages steady state concentration. When you micro dose with Reta, you get zero of the thermogenic benefits and more side effects.