Has anyone gotten labs and had your bloodwork get worse?

[ThunderBird]

We all hear about all the good but not so much the bad. Who has had the bad and what did that look like in your bloodwork?

 

[miameow]

Well define “worse” for me please, because most things just go slowly downhill as you age.

 

[ThunderBird]

Well define “worse” for me please, because most things just go slowly downhill as you age.

I’m not talking about a general trend, that is expected as you age as you pointed out haha. I’m more referencing something like you get bloodwork done, run a stack for 3 months, and get a blood test at the end. If something suddenly started trending or trended in the wrong direction. Either that you weren’t expecting or was an unintended consequence of your protocol. Sorry if my question was unclear.

 

[bada bing]

No
I've lost 50+ lbs twice in my life just using diet and now once with GLPs. I get bloodwork done anytime I make a significant lifestyle change. The changes with GLP are consistent with just dieting, with perhaps an advantage to GLP use. I've experienced pretty significant positive changes across my labs with a significant weight loss, no matter what method. In particular, HbA1c and blood pressure improve pretty rapidly. Inflammation markers and blood lipids as well to a lesser extent. My first attempt at shedding weight with diet was a negotiation with my PCP to keep from starting on blood pressure meds. It works.

It's nice to have objective measurements to show you're improving things and not screwing up.

 

[Builderman]

I’ve been on Reta for 4 weeks now and my blood pressure(which was pretty horrendous to begin, I’m very overweight and my family has bad heart history) has improved dramatically. My systolic has dropped 35 and my diastolic has dropped 29. And my resting heart rate has actually dropped 15bpm. I am also down 15 pounds. Even if some of my blood work came back bad, I feel the positive trend in these locations would far outweigh any “bad” bloodwork.

 

[RoadRash]

We all hear about all the good but not so much the bad. Who has had the bad and what did that look like in your bloodwork?

My blood work has improved by leaps and bounds, sorry to disappoint. The only negative has been resting heart rate, which went up 12-15 bpm. It's come down now, but still higher than normal.

 

[T.Bird]

My Bloods from last year to this year have been a vast improvement.

 

[jjplantgeek]

When I started with compounded tirz in October and told my doc in December, he wasn't a fan, said I wasn't "obese" (BMI 34.9, 277#). He agreed to monitor my bloodwork quarterly though. From my initial labs in October, to the first check in December, to my second check in Feb, my testosterone went from 770-850-1040. Doc didn't like these numbers and was concerned, was convinced that the compounding pharmacy was adding testosterone to the meds. I guess he thought that was "worse" but all my other numbers were significantly better. I told him to fuck off and found a new doc...

 

[bada bing]

There are more than few Docs who are taking low dose Tirz themselves while not being obese or diabetic. The evidence for it is pretty compelling, although no where near being made part of official guidelines. Remember that when dealing with Docs, many of them are doing things themselves they feel constrained from admitting or recommending.

It would be funny if they could put "GLP1 agonist deficiency" as a contributing cause on death certificates, because it's true in a lot of cases.

 

[Vegemite]

I’ve had blood work come back worse before but it wasn’t due to peptides but more due to running orals along side my stack.

 

[Meritocrat]

After my gastric surgery, all my liver enzymes were elevated. I had NAFLD and a few months later they were all fine along with other metabolic numbers. But some other numbers worsened with the weight loss, such as testosterone, IGF-1, etc. The hernia might be responsible for that, though.