Hi folks, I have a friend who is struggling with Tirz due to constant headaches. I'd like to try them on another option and I have a few - Reta, Sema, Maz, Survo... anyone out there that can speak to headache as a debilitating side effect, and if a specific med was better for you than others? TIA!
Headache with Tirz - next option to try?
- Thread starter cldfront
- Start date
100% it's a hydration problem that changing GLP's isn't going to solve.
They may also want to get some blood work done to see where things stand and if anything is out-of-whack to the point that it might be exacerbating the side-effects from dehydration.
They may also want to get some blood work done to see where things stand and if anything is out-of-whack to the point that it might be exacerbating the side-effects from dehydration.
GLP1Pharmacist
GLP-1 Enthusiast
Also are you checking blood pressure and blood sugar?
Common things like low iron, low vitamin D, low potassium and number of other things can make the side-effects of insufficient hydration worse, as can more serious things like diabetes. A basic CMP blood test even without insurance should be under $50 at most places like Quest, LabCorp, etc. and is totally worth it. Could also be as simple as an electrolyte imbalance so often water alone may not be terribly helpful.
Peotidethrowaway
GLP-1 Enthusiast
Add in some magnesium to your vitamins? It’ll help you poop and help with headaches.
peptideusername
Moderator
Liquid IV or similar will hydrate and electrolyte you at the same time. Plus the Firecracker Popsicle flavor of Liquid IV is delicious.
I like to mix one packet of Concord grape and one packet of (pink or blue) cotton candy in a gallon of water and that is the bomb.com
GLP1Pharmacist
GLP-1 Enthusiast
I still suggest a simple one a day vitamin too. Having a balanced diet can be even tougher with major reductions in food intake.
MsGizmo
GLP-1 Enthusiast
When you start eating less food its kind of important to prioritize getting enough water, fiber and protein. Its also not a bad idea to take a daily multivitamin.
geoguy78
GLP-1 Specialist
Other have alluded to the water situation, but also..... are they eating enough? It's super easy to barely eat, if at all on GLPs. Sometimes you have to force feed even when you don't want to in order to keep your caloric intake at a safe level. I find that when I'm in too much of a carb deficit I get headaches. Used to happen to me when I would try carb free or low carb diets as well.
latviantower
GLP-1 Apprentice
The CMP should also have a creatinine test, which I’m guessing this guy’s level is high due to dehydration. The compounding teledoc always checked my creatinine every six months. I’ve continued that CMP panel every six months since. With periodic sales through Life Extension, Labcorp is like $45. Worth it for peace of mind!
My hydration of choice is Body Armor Lyte - strawberry banana all day long.
I get the headache with it too. I drink enough, eat enough and all I can come up with is low blood glucose. I have it at night when I am sleeping. I am just aware enough to know my head is hurting. It lasts for 2 to 3 days post injection. I am not diabetic or pre diabetic. My AIC was 5.2 before I started the injections.
Peotidethrowaway
GLP-1 Enthusiast
I’m prone to headaches and I’m the opposite. No more daily headaches on tirz. The only working theory I have is reduced inflammation in the body affecting my brain or vessels in the brain somehow.
I wonder if that change can trigger headaches in other people 🤷♂️
lessthanhalf
GLP-1 Novice
As the headaches are described as constant and debilitating , and no one has said it yet, maybe checking them out with a doctor might be a good idea. There is no real information to even guess at what is going on to cause the headaches. No information on age, health or if medical advice has been sought. Are they new?, does the person often get headaches? have they been diagnosed with any particular type of headache before etc.
If you are taking on the role of doctor and advising someone on treatment options with glp medications ( which are prescription medications for a reason ) you really need to be very certain that you understand what is going on, and if you do not know exactly what is going on to cause the headaches, then medical advice is required especially as you are talking about someone else. If it is yourself then you can decide for yourself what risks you are happy to accept , but if treating or advising someone else then I would think great care needs to be taken that you do not inadvertently cause harm. It is unlikely that there is a serious problem here but if you do not know that for certain then the only reasonable approach is to get expert advice.
The desire to share the tremendously useful effects these medications have with others is perfectly reasonable, but some degree of medical supervision is definitely preferable, and in the very unlikely event of someone having a fatal side effect, you could be liable if you provided the medication, and if you provide the medication or even just advice there is very definitely a duty of care, whether you are qualified to provide it or not.
In general tirzepatide is not known to make migraines worse and may even help but headache is listed as a side effect in about 5% of patients in the studies, and there is a large number of possible reasons it could make headaches more likely, including changes in diet and fluid intake. The simplest experiment to see if tirzepatide is responsible for the headaches, is to stop it and see if they go away, but given it's long half life it might take a few weeks. Once a explanation for the problem exists, and the person may well have a known and medically treated cause for the headaches, but there is no information here to know one way or the other, then it might be time to work out what alternative medication might be suitable.
If you are taking on the role of doctor and advising someone on treatment options with glp medications ( which are prescription medications for a reason ) you really need to be very certain that you understand what is going on, and if you do not know exactly what is going on to cause the headaches, then medical advice is required especially as you are talking about someone else. If it is yourself then you can decide for yourself what risks you are happy to accept , but if treating or advising someone else then I would think great care needs to be taken that you do not inadvertently cause harm. It is unlikely that there is a serious problem here but if you do not know that for certain then the only reasonable approach is to get expert advice.
The desire to share the tremendously useful effects these medications have with others is perfectly reasonable, but some degree of medical supervision is definitely preferable, and in the very unlikely event of someone having a fatal side effect, you could be liable if you provided the medication, and if you provide the medication or even just advice there is very definitely a duty of care, whether you are qualified to provide it or not.
In general tirzepatide is not known to make migraines worse and may even help but headache is listed as a side effect in about 5% of patients in the studies, and there is a large number of possible reasons it could make headaches more likely, including changes in diet and fluid intake. The simplest experiment to see if tirzepatide is responsible for the headaches, is to stop it and see if they go away, but given it's long half life it might take a few weeks. Once a explanation for the problem exists, and the person may well have a known and medically treated cause for the headaches, but there is no information here to know one way or the other, then it might be time to work out what alternative medication might be suitable.
BooneDonk
GLP-1 Enthusiast
Medical advice from an Internet forum is wild! We are all here for reasons, but if I had a migraine for days and weeks; I would find an actual MD and spill the beans as I’m hoping OP has or plans to first of next week.
I am spoiled to having actual MDs as relatives admittedly, but please go find a doctor if this is your issue and same for all the crazy stuff I’ve seen people post. This isn’t a hospital! ER is kinda free (to you) if you walk a bill in the US!!
Agree…constant and debilitating…quite a dramatic description. Just go to the ER if they are that bad. I would think most people wouldn’t sit at home with a “constant and debilitating” headache but maybe some might think that’s okay…
All the obvious things were done before I posted here asking for tips, including a hiatus from Tirz to see if the headache went away (it did) and returned with the reintroduction of the med (it did). No cause for alarm with my situation, however I appreciate that not everyone reading along is savvy to the potentials of things. In case of any debilitating side, a doctor visit is always prudent.
I like to be succinct. To better explain for you, "constant and debilitating' was meant to describe a headache that only goes away with robust application of OTC pain meds and returns once those meds exhaust their cycle (constant), and is affecting daily life (debilitating) by making it hard to focus at work. Some might think it's okay to go to the ER for a headache I suppose, but we like to save that space for actual emergencies. In my area they're pretty swamped frying bigger fish.
Peotidethrowaway
GLP-1 Enthusiast
As someone that has suffered frequent headaches for 30 years I would only be super concerned if the headaches were intractable. I’m only mildly concerned that they’re new or changing. You seem to have it under control. Lecturing someone for asking for or giving advice is pretty wild. Sometimes this forum seems to go off the deep end thinking they’re experts on anything
Reta didn’t work for me, but that seems to be the most popular med besides tirz
I get the concern. No one here wants to hurt anyone. The advice given here is meant to help and not harm…but there is the potential to give advice that is harmful.
Everyone needs to remember that any advice received here is at your own risk.
Everyone needs to remember that any advice received here is at your own risk.
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